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Wed, 23 Jan 2019
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A hormone released during exercise might protect against Alzheimer's

cold swim lake
© Arctic Images/Getty
A hormone released during exercise may protect the brain against Alzheimer's disease. It may also explain the known positive effects of exercise on mental performance.

Irisin is a hormone generated by muscle tissue that is carried around the body in the bloodstream. Fernana de Felice at the Federal University of Rio de Janerio and colleagues found that people with Alzheimer's had lower levels of the hormone compared with healthy individuals.

In tests with mice, the team could induce learning and memory deficits by cutting out irisin and could reverse the effects by restoring the hormone. When irisin signalling was blocked in mice with a rodent version of Alzheimer's, the brain benefits of physical exercise were lost.

Comment: See also:


Briefcase

Physician scientists fail to disclose Big Pharma conflicts of interest in medical journals

deals
Medical doctors conducting scientific research are not accurately disclosing their financial ties to pharmaceutical and health care companies when their studies are published in medical journals, according to a recent article published by ProPublica in collaboration with The New York Times.1

A number of these doctors are prominent figures in the medical field. One example is Howard A. "Skip" Burris III, MD the president-elect of the American Society of Clinical Oncology. Dr. Burris declared that he has no conflicts of interest in over fifty journal articles, including those articles in the prestigious New England Journal of Medicine.1However, ProPublica reported that pharmaceutical companies paid his employer, Sarah Cannon Research Institute in Nashville, Tennessee approximately $114,000 for his speaking and consulting engagements and almost $8 million for his research during the time period when the disclosure of financial relationships and industry was required. One of those journals was the Journal of Clinical Oncology, published by the American Society of Clinical Oncology, the medical trade group he was elected to head.1

Comment: Conflicts of interest in the medical field: New law aims to expose Big Pharma influence on physicians
Over the years, the credibility of the medical profession from the patient's perspective has continued to decline because of the relationship between physicians and industry.1 It is now being realized that relationships between doctors and the pharmaceutical industry are a central public health issue that must regulated and contained within reasonable boundaries.1 A growing number of critics are pointing out the danger of the too-cozy relationship between doctors and drug companies and are beginning to push for more transparency around these murky relationships.



Biohazard

Worst measles outbreak in decades sweeps New York and abroad

measles

A body-covering red splotchy rash is the tell-tale sign of the measles infection
Cases of measles have reached a 20-year high in several New York counties amid an outbreak that threatens to reach epidemic proportions, experts say.

At least 160 people have been infected by the virus, which typically strikes children, in New York and unusual outbreaks have been reported internationally.

The worst affected areas so far are Rockland County - where 105 cases have been reported - and an Orthodox Jewish neighborhood in Brooklyn, where at least 55 have been infected.

Meanwhile, 25 other states have reported outbreaks, with numbers climbing particularly high in Oregon and Washington.

Comment: There is a wealth of evidence that demonstrates vaccination does not necessarily confer immunity, and, in some cases, has actually been linked back to the outbreaks themselves: Outbreaks of all kinds appear to be on the rise, for more links and information on the possible causes, see: 6 children dead after outbreak of life-threatening virus strain at New Jersey health facility - UPDATE: death toll now at 11

And for more on vaccines, check out SOTT radio's:


Cupcake Pink

Food additive linked to celiac disease: Transglutaminase

meat glue transglutaminase
If you have a severe intolerance to gluten, a chemical in your diet may (at least partly) be to blame.

We are not talking about gluten allergies or sensitivities here, but celiac disease - a lifelong autoimmune disorder affecting roughly one in 100 people where the ingestion of gluten provokes an immune system attack on the gut. Experts aren't sure of the exact cause. However, a paper recently published in Frontiers in Pediatrics has linked a common food additive to the disease: Microbial transglutaminase.

Transglutaminase is a bacterial enzyme often added to food during manufacturing. You can find it in a lot of processed food, from dairy and meat to baked goods.

Comment: What isn't mentioned in the above article is that microbial transglutaminase is otherwise known as "meat glue", an additive used to fuse proteins together. It's been known for awhile within the celiac community that this additive can cause a reaction in people with celiac (see Dr. Peter Osborne's piece about it here; written 2 years ago), but it's good that they're actually doing some scientific studies on it.

See also:


Brain

Number of people with dementia doubled in just 26 years

old couple holding hands
© Getty Images
The number of people living with dementia globally more than doubled between 1990 and 2016 from 20.2 million to 43.8 million, report researchers.

The researchers also found that 22.3 percent of healthy years lost due to dementia in 2016 were due to modifiable risk factors. Their study looks at the global, regional, and national burden of Alzheimer's disease and other dementias from 1990-2016.

The systematic analysis of the Global Burden of Disease Study 2016 found dementia was more common at older ages, with the prevalence doubling every five years over age 50. There was also significant potential for prevention.

Comment: The unstoppable tide of chronic disease continues to climb yet everyone still seems to have their hearts set on looking in the wrong directions for answers. The above article is correct in its addressing of lifestyle factors, but what is really needed is for researchers to start asking difficult questions, throwing away everything that is currently being taken for granted (like assumptions about diet) and stop looking for solutions in pharmaceutical interventions.

See also:


Cow

New Canada food guide to encourage Canadians to malnourish themselves by eating more plant-based protein

canada food guide
An overhaul of the Canada Food Guide is set to be released soon, a highly-anticipated makeover that will do away with the rainbow visual many Canadians associate with the dietary guide commonly used in hospitals and daycares.

One of the major changes expected in the new guide is a focus on plant-based sources of proteins - a move that has sparked concern among industry players, including the Dairy Farmers of Canada.

In a statement released Friday afternoon, the national policy and lobby organization representing Canada's farmers warned the decision could have a detrimental impact on future generations and harm a sector that continues to be "negatively impacted by the concessions granted in recent trade agreements."

Comment: Canada's Food Guide has always bee a complete farce, only ever conferring advice on how Canadians can make themselves fat and sick, so it isn't any wonder it's newest iteration is more of the same. This politically correct emphasis on encouraging the replacing of animal foods with vegetables and grains is doing no one any good. The only thing the Canada Food Guide should be used for is lighting fires and emergency toilet paper.

See also:


Cupcake Choco

Diabetes and obesity still on the rise - Billions spent promoting dietary guidelines hasn't made a dent

Prevalence of Diabetes by State, 2016–2017

Prevalence of Diabetes by State, 2016–2017
A new report on the continued alarming rise of diabetes in the U.S. illustrates how decades of government dietary guidance has thus far failed to contain this costly and debilitating disease.

As part of their State of American Well-Being series, Gallup and Sharecare found that 11.5% of the U.S. adult population was diagnosed with type 1 or type 2 diabetes in 2016-2017, up from 10.8% in 2008-2009.

The survey, released this month, saw diabetes rates vary widely by state, from a low of 8.4% in Alaska to a startling 17.9% in West Virginia. Worse, obesity in the United States climbed 2.3 percentage points to 28.3% nationally.

Comment: Any sensible person should be able to look at the strategy of the government nutritional guidelines have been using for the past decades and see that they clearly are not working. But rather than look at the emerging science and adjust accordingly, the researchers continue to double down on the same old advice. Either people are going to wake up to the mess that are the dietary guidelines, or they're going to die. It's basically Darwinism.

See also:


Cloud Precipitation

Seasonal affective disorder: Your eye color might be why you have the 'winter blues'

eyes
© Hanna Kuprevich/ Shutterstock
The amount of light your eyes can process might be one of the reasons why some people are more likely to experience SAD.
You're not alone if colder weather and longer nights make you feel down. This well-known phenomenon, called seasonal affective disorder (SAD), might explain why people feel low, irritable, and lethargic in the winter months. For some, the condition can be serious and debilitating.

Although SAD is a recognised form of clinical depression, experts are still divided on what causes the condition, with some even arguing it doesn't exist. But my own research has found that your eye colour might actually be one factor determining whether or not you develop SAD.

A survey I conducted in 2014 found that around 8% of UK people self-reported changes with the seasons that can be classified as SAD. Another 21% reported symptoms of sub-syndromal SAD, which is a less severe form, often called the "winter blues".

Comment: Read more about Healing the body with light:


Microscope 1

Natural Autoimmunity: Friend or Foe?

immunity
Rather than signifying an immune system gone haywire, pioneering research reveals that autoantibodies are a biological prerequisite, and that natural autoimmunity is the master orchestrator of physiological homeostasis.

When examining a lab report for autoantibodies, why is there a normal reference range? Classical immunology, adhering to the principle of "Horror autotoxicus," argues that any level of antibody against self represents loss of self-tolerance and compromised immunoregulatory mechanisms. Although clonal deletion and anergy have previously been conceived as processes by which self-tolerance develops, these concepts fail to explain the prevalence of natural autoimmunity among healthy individuals (1). Novel research is elucidating that autoimmunity is a natural, common phenomenon, and that autoimmune disease occurs as a secondary response to tissue or organ injury.

Info

Water fluoridation: Facts & fallacies

water
Water fluoridation has been around for just over 60 years and whilst the practice has become widespread, particularly in Western nations, it's always been a controversial and often passionately argued one.

My formative moment in the fluoride 'debate', one that cathartically shunted me into the anti-fluoride lobby's arms, came many years ago when I was sitting in a dentist's chair in Cambridge, UK.

I knew very little about fluoride at the time, so it was with an open mind and calm disposition that I opened my mouth in order for my dentist to pour in some fluoride solution which he said would give my teeth a strong protective coating. The problems started immediately after having dispensed the liquid into my mouth when he stammered, "...but don't whatever you do swallow it!" "Why?" I gurgled, "Because it's poisonous and could kill you," came his reply.

Comment: More benefits of Iodine: Protection against fluoride toxicity