© Maksim Plikus, University of California, IrvineResearchers have discovered a new type of cartilage cell called lipo-chondrocyte, that is filled with large fat droplets (shown here in green) and is found in many mammalian species.
A newly identified cartilage cell generates fat vacuoles and makes the surrounding tissues pliable. This helps keep the ear and nose tips bouncy.The smooth functioning of the body's joints, the flexibility of the ears and nose, and the shaping of bones are all made possible by the skeletal tissue known as
cartilage.
1 According to popular medical textbooks, cartilage is made up of only one type of specialized cell called a
chondrocyte, which is small and secretes large quantities of extracellular matrix, giving cartilage its biomechanical properties.
2 But now, new research makes these textbooks outdated.
More than a decade ago, while studying fat cells in the mouse ear skin,
Maksim Plikus and his colleagues observed a puzzling pattern in dye uptake. "There were some fat cells that stained, which were the true adipocytes," said Plikus, a developmental biologist at the University of California, Irvine. "Then there was another group of fat cells that didn't [stain], no matter which marker." Initially, he thought these odd adipocytes could simply be a type that stubbornly resisted dyes. However, upon digging deeper, Plikus realized that they were a completely new type of fat-laden cartilage cells that formed the pliable lipo-cartilage in body parts like the nose, ear and throat. "At first we really had to pinch ourselves because it made no sense," Plikus exclaimed.
Comment: There's a lo more to Mercury than amazing photos, as other probe have revealed: