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The smallpox vaccine was first developed in 1775, credited to Edward Jenner, who first experimented with an eight year-old boy named James Phipps. Jenner claimed that the procedure of injecting cowpox pus prevented smallpox and he convinced King George that his vaccine would eliminate smallpox. King George awarded Jenner the equivalent of half a million dollars to inoculate the public against smallpox.
After widespread vaccinations, the Smallpox Hospital in London reported a steady, disturbing increase in smallpox cases, rising from 5% to 96% by 1885. Mortality rates from smallpox also rose. The smallpox vaccine caused many diseases including syphilis, tuberculosis and leprosy.
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