
© ShutterstockThe study diet mimicked ready-to-eat human foods that are often packaged for long shelf lives, such as salty snacks, frozen entrees and deli meats containing preservatives.
Four weeks on a diet of highly processed food led to a strong inflammatory response in the brains of aging rats that was accompanied by behavioral signs of memory loss, a new study has found. Researchers also found that supplementing the processed diet with the omega-3 fatty acid
DHA prevented memory problems and reduced the inflammatory effects almost entirely in older rats.
Neuroinflammation and cognitive problems were not detected in young adult rats that ate the processed diet.
The study diet mimicked ready-to-eat human foods that are often packaged for long shelf lives, such as potato chips and other snacks, frozen entrees like pasta dishes and pizzas, and deli meats containing preservatives.
Highly processed diets are also associated with obesity and type 2 diabetes, suggesting older consumers might want to scale back on convenience foods and add foods rich in DHA, such as salmon, to their diets, researchers say - especially considering harm to the aged brain in this study was evident in only four weeks.
"The fact we're seeing these effects so quickly is a little bit alarming," said senior study author
Ruth Barrientos, an investigator in The Ohio State University
Institute for Behavioral Medicine Research and associate professor of
psychiatry and behavioral health.
"These findings indicate that consumption of a processed diet can produce significant and abrupt memory deficits - and in the aging population, rapid memory decline has a greater likelihood of progressing into neurodegenerative diseases such as Alzheimer's disease. By being aware of this, maybe we can limit processed foods in our diets and increase consumption of foods that are rich in the omega-3 fatty acid DHA to either prevent or slow that progression."
The research is published in the journal
Brain, Behavior, and Immunity.
Comment: See also: Social contagion: A mysterious spike in Tourette's leads back to YouTube star