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A paper published in January raised the possibility that the pandemic could make some people more susceptible to chronic conditions and diseases, including asthma and obesity.
The good news is that frequent hand-washing, masks and physical distancing work. Falling daily COVID-19 case counts in Ontario and across Canada testify to that.

Comment: Masks have little to no effect on the spread of viruses; and can excessive handwashing and distancing be said to 'work', when on the very next line the author admits that it actually makes one more susceptible to illness?

The bad news? Being hyper vigilant about hygiene could have some serious health consequences down the road.

In a paper published in January, members of the Canadian Institute For Advanced Research's humans and microbiome program raised the possibility the pandemic could profoundly change the human microbiome, making some people more susceptible to chronic conditions and diseases, including asthma and obesity.

"The COVID-19 pandemic has the potential to affect the human microbiome in infected and uninfected individuals, having a substantial impact on human health over the long term," wrote the authors in the paper that was published in the journal Proceedings of the National Academy of Science in the U.S.

University of British Columbia microbiologist Brett Finlay, who is the lead author, calls the pandemic a real-time experiment into the impact of necessary public health measures on the microorganisms that contribute to peoples' overall health.

"It gives us an experiment that you can't normally do: If you lock people up for a year, does it have long-term consequences?" said Finlay. The paper, he said, is a call for scientists to study the issue, especially its impact on young children.

The microbiome is made up of the microbes living on and in the human body that play a role in human health and disease. Changing that with use of antibiotics or by limiting contact with microorganisms, especially in early childhood, can have health consequences.

Comment: And not just the microbiome, research suggests there's more than just that which lives directly on us, there's the life that surrounds us, which also interacts with everyone we meet: "Exposome": Scientists measure invisible clouds of matter that orbit every human being

The so-called hygiene hypothesis in medicine says that early childhood exposure to certain microorganisms protects against allergic diseases and contributes to the development of the immune system.

Although sanitation and distancing to prevent the spread of the SARS-CoV-2 virus (which causes COVID-19) are necessary to protect human life, scientists warn in the paper that people should be ready for changes to the human microbiome as a result.

That could result in health consequences. Allergic responses, asthma, obesity and diabetes have all been linked to changes in the human microbiome in recent decades due, in part, to less exposure to microorganisms.

Finlay, who is author of the book Let Them Eat Dirt, said research has demonstrated there are consequences to living in a "hyper hygienic" society.

He said growing rates of obesity, asthma, inflammatory bowel disease and other conditions, especially in children, have been linked to exposure to fewer microbes.

Children who grow up on farms, for example, have lower rates of asthma and allergies.

Finlay has done research in British Columbia that links a significantly higher risk of asthma to antibiotic use in infancy. Use of antibiotics in infants has been reduced in B.C. over the last decades, something that has been matched by a reduction in rates of asthma.

He said the research paper published earlier this month was a call for people to be aware of the possible downstream impact of actions being taken during the pandemic.

"We know, based on history, that there are consequences."

Physical distancing, alone, makes a difference to people's exposure to microbes, something that is especially crucial for infants, he said.

"A child born today in a COVID world, who is that kid interacting with? They are not getting the microbes they are normally exposed to. We know in early life it is really important to have diverse microbial exposure, and that is just not happening in COVID, so I think there is some significant concern about what goes on there."

He said some of the impact of lack of contact with other people and places can be countered by eating a diet rich in fibre found in grains, fruits, nuts and vegetables, exercising, having contact with pets and getting outside as much as possible.

Comment: The suggested diet will increase disease in the vast majority. And, during the endless and rolling lockdowns, governments have made leaving the house and interacting with others an increasingly risky prospect, with numerous examples of house raids and on the spot fines for being outside, so it's a fact that everybody is getting much less fresh air and exercise, and much less contact with others.

He said it is important that children are able to go outside and play "in the environmental microbes" instead of staying indoors.

Meanwhile, he said studying the impact could provide valuable information.

"We have really drastically changed society in the last year and we know these often result in significant changes in the microbiome. It is a wonderful experiment. We are in a position to look at these things, so we need to use this opportunity to really examine this and learn from it."