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"Anyone that says, 'Oh, we know that this is perfectly safe,' I say is either unbelievably stupid, or deliberately lying. The reality is, we don't know. The experiments simply haven't been done, and now we have become the guinea pigs." ~ David Suzuki, geneticist
What we do know is that the unintended consequences of the recombinant DNA process employed to create genetically engineering organisms are beyond the ability of present-day science to comprehend. This is largely due to the post-Human Genome Project revelation that the holy grail of molecular biology, the overly-simplified 'one gene > one trait' model, is absolutely false.
Only recently, for instance, a previously unidentified viral gene fragment was discovered to be present in most of the GM crops commercialized to date; a finding which calls into question the safety of 54 commercialized crops already commercialized and being used in both food and feed. There could be hundreds of viral-gene altered proteins within these foods, whose complex interactions with DNA and toxicity have never been characterized.
Comment: To learn more about antibiotic resistant 'Superbugs' read the following articles: