Two studies have pinpointed a single gene as key to the development and treatment of schizophrenia.
© BBC NewsSchizophrenia Brain Scan: Schizophrenia can have devastating symptoms
A US team from the Howard Hughes Medical Institute found that a mutated version of the DISC1 gene disrupts the growth and development of brain cells.
And a team from the University of Edinburgh showed that the gene affects how patients respond to treatment.
Both studies, published in the journals PLoS One and Cell, raise hopes of more effective treatment for schizophrenia.
The condition is a common form of mental illness, affecting up to 1% of adults worldwide.
DISC1 GENE
*Linked in the early 1990s to mental illnesses prevalent in a large Scottish family
*Over five generations many family members had developed schizophrenia, bipolar disorder, and other mood disorders
*Each family member diagnosed with mental illness also carried a mutated copy of
DISC1