It is widely accepted that antioxidants in the diet and supplements are one of the most effective ways of preventing cancer. Nevertheless, Dr. James Watson has recently suggested that antioxidants cause cancer and interfere with its treatment. James Watson is among the most renowned of living scientists. His work, together with that of others (Rosalind Franklin, Raymond Gosling, Frances Crick, and Maurice Wilkins) led to the discovery of the DNA double helix in 1953. Although his recent statement on antioxidants is misleading, the mainstream media has picked it up, which may cause some confusion.
Antioxidants: What's Going OnDr. Watson claims to have discovered that antioxidants promote the growth of late stage metastatic cancers. He says that this is "among my most important work since the double helix." [1] We agree that the finding is fundamentally important, although it was not uniquely Watson's discovery. Rather, it is standard orthomolecular medicine and has been known for years. [2,3] Within the body, antioxidant levels act as a signal, controlling cell division. In healthy cells and benign tumors, oxidants tend to increase cell proliferation, whereas antioxidants inhibit it. By contrast, the malignant tumor environment can be so strongly oxidizing that it is damaging and triggers cell death by apoptosis. In this case, antioxidants may help tumor cells proliferate and survive, by protecting the cells against oxidation and stimulating the malignancy to grow. For this reason, antioxidants may sometimes be contraindicated for use with malignant tumors, although there are particular exceptions to this.
And Oxidants?The balance between oxidants and antioxidants is a key issue in the development of cancer, as has been known for decades. Watson appears to be behind the times in his appreciation of nutritional medicine and, surprisingly, to have misunderstood the processes of oxidation and reduction as applied to cancer. He correctly asserts that reactive oxygen species are a positive force for life; this is basic biology. They are also involved in aging, chronic illness, and cancer. Oxidants also cause free radical damage, thus the body generates large amounts of antioxidants to prevent harm and maintain health.
Comment: For more information on how to start a sugar-less diet, check our forum thread Life Without Bread.