
© ExtremeTech
Somebody should check and make sure that Kim Dotcom hasn't started funding any research in genetics. Maybe those guys from the Pirate Bay, too. With a paper that must send chills of fear and vindication down the spine of every internet freedom fighter, researchers from Cornell University this week presented evidence that genetic copyright is a "direct threat to genomic liberty." Could this be the newest, most easily altruistic frontier in copyright banditry?
The study in question looked at existing patented stretches of DNA, notably in the hotly contested BRCA1 gene [1], and set about testing whether these patented sequences might pop up elsewhere due to chance or redundant function. They searched the human genome for small and large sequences patented under just a single diagnostic test, and found that these sequences existed in 689 other places.
This isn't all that surprising. As the researchers point out, take any 15-nucleotide sequence (a '15mer'), check it against the human genome, and you'll always find a match somewhere else. In medicine researchers are generally selecting stretches of DNA for some sort of useful function, and evolution happens to like useful things, too; if we can't construct a 15mer
at random and find it only once in the genome, how could we possibly hope a medically useful one, one with a distinct selective advantage, will be unique? The code for several types of protein motifs, most of which are much longer than 15 nucleotides, are repeated literally
thousands of times in humans. (See: Your complete DNA genome can now be sequenced from a single cell [2].)
[3]That certainly sounds scary, but doesn't this all seem just a little alarmist?