Having too little thyroid hormone in the blood--
even in the low-normal range--raises the risk of developing Type 2 diabetes, especially in people with prediabetes, a new study in nearly 8,500 people finds. The study results will be presented Sunday at the Endocrine Society's 98th annual meeting in Boston.
Prediabetes is a mild elevation in blood glucose, or sugar, level that usually occurs before diabetes develops. One of every 10 people with prediabetes will develop Type 2 diabetes every year, according to the Hormone Health Network.
In the new study, the risk of developing Type 2 diabetes over long-term follow-up
increased by 13 percent for people with low thyroid function--often called underactive thyroid gland or hypothyroidism--or even those with low-normal thyroid function. However,
the diabetes risk was up to 40 percent higher for individuals with reduced thyroid function if they already had prediabetes, the investigators reported.
"These findings suggest we should consider screening people with prediabetes for low thyroid function," said lead investigator Layal Chaker, MD, of Erasmus Medical Center, Rotterdam, the Netherlands.
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