
© U.S. Navy photo by Mass Communication Specialist 3rd Class Jake Berenguer/WikicommonsBlood banks run blood type tests before blood is sent to hospitals for transfusions.
Everyone's heard of the A, B, AB and O blood types. When you get a blood transfusion, doctors have to make sure a donor's blood type is compatible with the recipient's blood, otherwise the recipient can die. The ABO blood group, as the blood types are collectively known, are ancient.
Humans and all other apes share this trait, inheriting these blood types from a common ancestor at least 20 million years ago and maybe even earlier, claims a new study published online today in
Proceedings of the National Academy of Sciences. But why humans and apes have these blood types is still a scientific mystery.
The
ABO blood group was discovered in the first decade of the 1900s by Austrian physician
Karl Landsteiner. Through a series of experiments, Landsteiner classified blood into the four well-known types. The "type" actually refers to the presence of a particular type of antigen sticking up from the surface of a red blood cell.
An antigen is anything that elicits a response from an immune cell called an antibody. Antibodies latch onto foreign substances that enter the body, such as bacteria and viruses, and clump them together for removal by other parts of the immune system. The human body naturally makes antibodies that will attack certain types of red-blood-cell antigens.
For example, people with type A blood have A antigens on their red blood cells and make antibodies that attack B antigens; people with type B blood have B antigens on their red blood cells and make antibodies that attack A antigens. So, type A people can't donate their blood to type B people and vice versa. People who are type AB have both A and B antigens on their red blood cells and therefore don't make any A or B antibodies while people who are type O have no A or B antigens and make both A and B antibodies. (This is hard to keep track of, so I hope the chart below helps!)