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The researchers had previously found that cannabinoid receptors can stimulate bone formation. In the new study, the team injected rats that had broken thighbones with either CBD alone, or a combination of CBD and THC (tetrahydrocannabinol, the hallucinogenic ingredient in marijuana).
The researchers found that CBD enhanced bone healing by strengthening the cartilage "bridge" that forms when a bone is on the mend. This bridge is called the fracture callus; it's made of collagen, which then gradually mineralizes and hardens into new bone.
In rats treated with CBD, this collagen tissue was stronger, and the collagen molecules more tightly cross-linked with one another, compared to rats not treated with the marijuana compound. What this means, researchers wrote online May 10 in the Journal of Bone and Mineral Research, is that the healed bone in CBD-treated rats is less likely to break in the future compared to the healed bone in untreated rats. In fact, the treated bone is between 35 percent and 50 percent stronger.
THC was not necessary to get this bone boost, the researchers also found.
Comment: Read more about the abuse of antibiotics in factory farmed animals and the rise of 'super bugs':