
© LIFEHistoplasma capsulatum
A 70-year-old patient who presented with cancer-like symptoms turns out to have been harbouring something even weirder: a fungal infection that may have been in his body for 30 years before making itself known.
It turns out what he had was
a disease called histoplasmosis - a condition caused by inhalation of the spores of a fungus called Histoplasma capsulatum.He presented to the hospital complaining of "altered mental status" for four days, according to the
case report - he seemed otherwise normal, but a bit confused. A CT scan, followed by an MRI, showed a lesion on his brain, and his doctors feared the worst: metastatic malignancy.
When they conducted further MRI scans, they also found masses in both his adrenal glands. But they did not suspect histoplasmosis. Partially because
histoplasmosis, as it is inhaled, mainly presents in the lungs. Mainly, however, because the patient lived in Arizona, and had not left the state for many years. Histoplasmosis, also known as cave disease, is
fairly common in areas such as the Mississippi and Ohio river valleys, but not Arizona.
Comment: Victorian diseases like scurvy and scarlet fever increase in the UK