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According to the Centers for Disease Control and Prevention (CDC), "Immunity to a disease is achieved through the presence of
antibodies to that disease in a person's system."[i] This, in fact, is the main justification for using vaccines to "boost" immunity, and a primary focus of vaccine research and development.
And yet, newly publish research has revealed that in some cases
no antibodies are required for immunity against some viruses.
Published in the journal
Immunity in March, 2011, and titled, "B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity," researchers found that mice infected with vesicular stomatitis virus (VSV) can suffer fatal invasion of their central nervous system even in the presence of high concentrations of "neutralizing" antibodies against VSV.[ii]
The researchers found that while B-cells were essential for surviving a systemic VSV infection through the modulation of innate immunity, specifically macrophage behavior, the antibodies they produce as part of the adaptive immune response were "neither needed nor sufficient for protection." These findings, according to the study authors, "...contradict the current view that B cell-derived neutralizing antibodies are absolutely required to survive a primary cytopathic viral infection, such as that caused by VSV."
The discovery that antibodies are not required for protection against infection, while counterintuitive, is not novel. In fact, not only are antibodies not required for immunity, in some cases high levels are found in the presence of active, even lethal infections. For example, high serum levels of antibodies against tetanus have been observed failing to confer protection against the disease. A report from 1992 published in the journal
Neurology found
severe tetanus in immunized patients with high anti-tetanus titers, one of whom died as a result of the infection.[iii]
These research findings run diametrically opposed to currently held beliefs regarding the process by which we develop immunity against infectious challenges. Presently, it is a commonly held view that during viral infections, innate immunity
must activate adaptive responses in order to achieve effective immunity. It is believed that this is why the immune system has developed a series of innate defenses, including complement, type I interferon, and other "stopgap measures," which work immediately to lower pathogen burden and "buy time" for the much slower adaptive immune response to develop.
Comment: To learn more about the misuse and overuse of antibiotics in Factory Farms and Why Factory Farms Threaten Your Health read the following articles:
Factory Farms Make You Sick. Let Us Count the Ways
What the USDA Doesn't Want You to Know About Antibiotics and Factory Farms
Got Antibiotics in Your Food? Thank the FDA
The FDA Finally Reveals How Many Antibiotics Factory Farms Use