Firefighters in Granada, near Bogota, said two people were injured in the Sunday morning blast, including a driver who was passing by at the time of the explosion.
The Crue emergency center of Cundinamarca province said the driver suffered shrapnel wounds on his right arm and was released following treatment.
Carlos Espinoza, the man filming the explosion, was thrown by the force of the blast, the video shows.
Authorities said the factory blast and ensuing fire destroyed five warehouses that were being used to store gunpowder.
Provincial Gov. Alvaro Cruz said the cause of the explosion is under investigation.
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