People with fibromyalgia (FM) may suffer from the inability to absorb amino acids. Significantly low amino acid levels have been found in the blood patients with fibromyalgia.
In malabsorption, nutrients are not absorbed into the body for utilization. This results in a deficiency which is not linked to poor diet.
Overall amino acid levels in test subjects were very low, especially those of taurine, alanine, tyrosine, valine, methionine, phenylalanine, and threonine.
Scientists have also linked certain amino acids to the clinical symptoms of fibromyalgia. The lower the level of these certain amino acids, the more pain the patient reports.
FM is a disease process characterized by chronic widespread musculoskeletal pain, non-restorative sleep, fatigue, headache, morning stiffness, poor memory, difficulty concentrating, paresthesias (numbness and tingling) and overall impaired functioning in both social and occupational settings.
The severity of the pain is typically more constant than other forms of pain and may come and go rapidly, move around to various parts of the body, and worsen with touch. For example, some fibromyalgia patients find their own clothing against their skin painful, particularly if it is tight clothing.
Fibromyalgia is the 2nd most common disorder seen by rheumatologists, affecting roughly 2% of the population of the United States. Middle aged women are afflicted at a higher rate, with a prevalence of 3.4% for women, and 0.5% for men.
Despite this new discovery, taking amino acid supplements may not be useful if they cannot be absorbed.
Additional research into the cause of malabsorption is necessary to ascertain the reasons for low uptake. An amino acid profile can be prescribed to determine and monitor amino acid levels.
Reference:
Bazzichi L, Palego L, Giannaccini G, Rossi A, De Feo F, Giacomelli C, Betti L, Giusti L, Bombardieri S, Lucacchini A. "Altered amino acid homeostasis in subjects affected by fibromyalgia." Clin Biochem. 2009 Mar 9. [Epub ahead of print]
This article originally appeared in the MCS America News, April 2009 Issue.
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Taurine Promotes Axonal Sprouting Through Mitochondrial Improvement in Stroke [Link]
Results
TAU treatment significantly recovered the motor function of focal cerebral cortical ischemic mice. And TAU promoted axonal sprouting. It was also observed that TAU enhanced mtDNA content, increased the levels of Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PCG-1a) and Transcription factor A of mitochondria (TFAM).
Taurine – a wonder molecule. Proceedings of the 17th International Taurine Conference -- Taurine in health and diseases: consistent evidence from experimental and epidemiological studies [Link]
Protective effects of taurine against inflammation, apoptosis, and oxidative stress in brain injury [Link]
Taurine Protects against Postischemic Brain Injury via the Antioxidant Activity of Taurine Chloramine [Link]
startpage.com search "taurine stroke recovery"
Neuroprotective Mechanisms of Taurine against Ischemic Stroke (2013) [Link] How to quickly repair energy after a concussion or stroke [Link] ---
Self-experimenters at raypeatforum.com have used 15g taurine per day for a month to build up large stores. Personally, 3g doses 5x/day had no notable side effecs over 7 days. Niacinamide, vitamin B3, can be used at 1g dose 6x/day as a precursor to build up NAD+ (nicotinamide adenine-dinucelotide) stores, but recommendations from self-experimenters would point at low levels of 100mg 3x/day being better and more sustainable. Others have used niacminade at the higher doses for long periods to help with alcohol and nicotine addiction, but potential side-effects including sedation should be researched. I think you should consider supplementing taurine at the level of 3g or 5g 5x or 3x per day, or as you see fit, but that 15g is tolerable and could translate to improved recovery from stroke.
RSVP