Health & WellnessS


Beer

Alcohol activates cellular changes that make tumor cells spread

Alcohol consumption has long been linked to cancer and its spread, but the underlying mechanism has never been clear.

Now, researchers at Rush University Medical Center have identified a cellular pathway that may explain the link.

In a study published in the current issue of Alcoholism: Clinical and Experimental Research, the researchers found that alcohol stimulates what is called the epithelial - to - mesenchymal transition, in which run-of-the-mill cancer cells morph into a more aggressive form and begin to spread throughout the body.

"Our data are the first to show that alcohol turns on certain signals inside a cell that are involved in this critical transition," said Christopher Forsyth, PhD, assistant professor of medicine and biochemistry at Rush University Medical Center and lead author of the study.

Alarm Clock

Tweens Challenged by Grown-Up Malady: Breast cancer

Hannah Powell-Auslam of La Mirada, California, had surgery this month to check her lymph nodes, just in case the breast cancer had spread.

Taylor Thompson of Little Rock, Arkansas, also had an aggressive form of breast cancer, one that has a 98 percent chance of returning. It required surgery in June.

They're two young women fighting breast cancer. Or rather, two girls: Hannah is 11. Taylor is 13.

While Taylor and Hannah's cases are rare, they're extreme examples of a troubling trend emerging with breast cancer, medical experts say. Younger women are getting a disease that usually strikes around menopause -- and no one knows why.

Attention

Hold the MSG: Food Triggers for Epilepsy and Other Neurological Illnesses

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Last week, 60 Minutes reported on David and Susan Axelrod's search for a cure for epilepsy prompted by their two decade plus experience of the ailment, which their adult daughter has suffered since infancy. But while Katie Couric admiringly covered the researchers seeking to find "the Cure," ie. new anti-convulsive drugs, once again proactive, preventive health care strategies that might help to reduce incidence of epileptic attacks were overlooked.

How ironic it is that in the midst of the health care reform debate, Axelrod, a key Obama aide, is so poorly informed about integrative strategies that could help his own daughter.

Syringe

Does the Vaccine Matter?

Whether this season's swine flu turns out to be deadly or mild, most experts agree that it's only a matter of time before we're hit by a truly devastating flu pandemic - one that might kill more people worldwide than have died of the plague and aids combined. In the U.S., the main lines of defense are pharmaceutical - vaccines and antiviral drugs to limit the spread of flu and prevent people from dying from it. Yet now some flu experts are challenging the medical orthodoxy and arguing that for those most in need of protection, flu shots and antiviral drugs may provide little to none. So where does that leave us if a bad pandemic strikes?

Heart

Flexibility Exercises Like Pilates and Yoga Could Prevent, Treat Stiff Arteries

From a sitting position, how far can you reach past your toes? Especially if you are middle-aged or older, the answer could indicate how flexible you are -- and also how flexible your arteries are. However, if you are stiff and can't reach too far, don't despair. New research suggests stretching exercises that increase flexibility could prevent or reverse stiffening of arteries.

In a study entitled "Poor trunk flexibility is associated with arterial stiffening", just published in the October edition of the American Journal of Physiology, researchers found that how well people age 40 and older performed on a sit-and-reach-past-their-toes test was an accurate way to assess the flexibility of their arteries. So, because arterial stiffness often precedes cardiovascular disease, this simple, non-drug, non-invasive test could become a quick measure of a person's risk for early death from heart attack or stroke.

Cheeseburger

The Axis of Food Evil: Fat, Sugar and Salt

Foods
© CBS NewsIt's hard to stay thin when all around us are fried, sugary, salty treats advertised wherever we turn.
Ex-Surgeon General Says restaurants overload foods with ingredients we crave, but they're just selling what we desire

The next time you come down with a case of the munchies, consider calling on Dr. David Kessler.

He and Altschul recently made a take-out run to some of America's most popular dining spots - the ones whose ads promise total tastebud-overload, like Chili's, Friday's, and Applebee's.

We brought back loads of goodies, but Dr. Kessler provided the real food for thought.

"The fat, the sugar and salt have been layered and loaded into this food," he said. "If I just gave you a package of sugar and say, 'Go have a good time' - "

"I'd pass," said Altschul.

Magnify

Scientists Discover Link between Older Dads and Genetic Diseases

Scientists have moved a step closer to understanding why older fathers are more likely to have children with certain genetic diseases.

They have discovered a surprising genetic link between the formation of benign testicular tumours called spermocytic seminomas and several rare growth disorders, which are more common among the children of older fathers.

The abnormal testicular cells that form these rare tumours also produce sperm carrying mutant genes that cause serious inherited diseases, research at the University of Oxford and Copenhagen University Hospital in Denmark has shown.

The findings offer important new insights into the origin of several rare genetic disorders, including a cause of dwarfism called achondroplasia, and also promise to illuminate more common conditions such as autism, schizophrenia and breast cancer.

Magnify

Why Sleeping On It Helps

Sleep
© Unknown
We're often told, "You should sleep on it" before you make an important decision. Why is that? How does "sleeping on it" help your decision-making process?

Conventional wisdom suggests that by "sleeping on it," we clear our minds and relieve ourselves of the immediacy (and accompanying stress) of making a decision. Sleep also helps organize our memories, process the information of the day, and solve problems. Such wisdom also suggests that conscious deliberation helps decision making in general. But new research (Dijksterhuis et al., 2009) suggests something else might also be at work - our unconscious.

Previous research suggests that sometimes the more consciously we think about a decision, the worse the decision made. Sometimes what's needed is a period of unconscious thought - equivalent to "sleeping on it" according to the researchers - in order to make better decisions. Here's how they study this phenomenon:
[... In a] typical experiment demonstrating this effect, participants choose between a few objects (e.g., apartments), each described by multiple aspects. The objects differ in desirability, and after reading the descriptions, participants are asked to make their choice following an additional period of conscious thought or unconscious thought. In the original experiments, unconscious thinkers made better decisions than conscious thinkers when the decisions were complex.

Attention

GM food can cause cancer

French scientist Gilles-Eric Séralini unmasked the dangers of genetically modified brinjal, almost approved for commercial production in India. He shared with Savvy Soumya Misra his findings on Bt brinjal and Roundup Ready soybean.

On the data submitted on Bt brinjal by Mahyco for approval from the Indian government

The data submitted to the Genetic Engineering Approval Committee (GEAC) of the Union environment ministry is not valid; it has not been signed by the scientist who conducted the tests. What is more scandalous is that the studies on the effects of Bt brinjal were conducted for just three months.

If the product is to be consumed by humans, the tests should have been for a period of at least two years - the lifespan of a rodent.

Worse, Mahyco tried to cover up the side-effects by jumbling data on various types of brinjal in a way that it was hard to compare Bt brinjal with normal brinjal. I am sorry to say people in the GEAC did not carefully assess the data. It is also not clear how the GEAC overlooked the fact that Bt brinjal has a protein that induces resistance to antibiotics. Mahyco has not studied hormonal impacts of Bt brinjal - Bt toxin found in it could lead to reproductive health problems.

Magnify

Herbicides and Cholesterol Drugs Interfere with Taste, Could Damage Metabolism

It's not unusual to hear about herbicides having suspected toxic effects or prescription drugs producing side effects. But a new National Institutes of Health (NIH) funded study just published in the Journal of Medicinal Chemistry has found another negative and surprising way common herbicides and fibrate drugs (which are used to lower elevated blood lipids) impact the human body: they block a nutrient-sensing taste receptor on the tongue called T1R3.

So what's the big deal about this? It turns out there's emerging evidence these taste receptors are also found in hormone-producing cells in the intestine and pancreas. When working properly, these internal taste receptors in the gut trigger the release of hormones involved in the regulation of normal homeostasis (the ability of the body to maintain internal physiological stability) of glucose as well as energy metabolism. Simply put, screwing up the ability of T1R3 to sense certain nutrients could possibly wreak havoc on the human body in a variety of ways -- from playing a role in unhealthy blood sugar levels to causing people to gain weight .

"Compounds that either activate or block T1R3 receptors could have significant metabolic effects, potentially influencing diseases such as obesity, type II diabetes and metabolic syndrome," said Monell geneticist and study leader Bedrich Mosinger, MD, PhD, in a statement to the media.