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© Jennifer Ingall
The Victorian Department of Primary Industries wants local vets to help identify a mystery horse disease.

Horses living along the Murray River and near Ballarat have become sick with a virus believed to be spread by mosquitoes.

Acting chief veterinary officer Andrew Cameron says he wants local vets to send samples from any sick horses to the DPI.

"I believe the most common symptom is sort of ataxia or wobbliness, more or less drunken horse like staggering about," he said.

"But there have been other neurological signs, twitching, blindness and this kind of thing.

"Some horses are also more severely affected."

Two deaths have been recorded as a result of the virus.