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Emergency workers rescued two injured people from a collapsed three-story home in the city in the Netherlands and are looking for anyone else who might have been killed or injured.
At least seven people have been taken to nearby hospitals, The Hague fire department said.
RTL News said a blast of unknown origin had caused three houses to collapse. It said nearby residents had been evacuated as a precaution.
A story and photograph published by local news service Omroep West said a single building had collapsed after a blast and emergency services were at the scene.
City emergency services spokesman John Kardol said it was unclear how many people were missing when the home was destroyed.
Mr Kardol said the two people found in the dwelling were taken to the hospital and the extent of their injuries was unclear.
Police at the scene said a gas explosion was being explored as a possible cause.
The blast tore off the home's front and demolished the dwelling, damaging nearby homes and cars.
Debris covering part of the street and parked vehicles complicated the search.
There was no immediate word on possible casualties.
Remember the "gas" explosion in France recently? We need some demolition and or fire engineers to look at this! Can a massive gas-fireball explosion needed to dislodge so much brickwork leave no burn marks/black areas? To me it looks more like a few drilled-in explosive charges, and even moreso it looks like damages from an excavator (like when the demolish buildings).
Who lived there or supposedly lived there? - Is this an accident, a homecide or simply just fear-porn to control the brave Dutch people?