© J. Heath, R. Fan, and H. AmadThis figure represents an artist's drawing (more or less to scale) of the channel through which the whole blood is flowed, and three of the plasma-skimming channels. The cells shown are mostly red blood cells, with a few white blood cells and platelets. Barcodes are shown in each of the three plasma-skimming channels, and the expanded view of a barcode illustrates some of the salient aspects of the assay. The different colors of the stripes correspond to different stripes of ssDNA.
A new "barcode chip" developed by researchers at the California Institute of Technology (Caltech) promises to revolutionize diagnostic medical testing. In less than 10 minutes, and using just a pinprick's worth of blood, the chip can measure the concentrations of dozens of proteins, including those that herald the presence of diseases like cancer and heart disease.
The device, known as the Integrated Blood-Barcode Chip, or IBBC, was developed by a group of Caltech researchers led by James R. Heath, the Elizabeth W. Gilloon Professor and professor of chemistry, along with postdoctoral scholar Rong Fan and graduate student Ophir Vermesh, and by Leroy Hood, president of the Institute for Systems Biology in Seattle, Washington.