
© Cema | sxc.huLike an alarm clock, the brain's internal clock can reset itself.
The brain's internal clock keeps time via a synchronized network of cells that is able to reset itself, a new study reveals.
This resetting may be what enables us to change our own daily rhythms with the seasons while the clock itself remains fairly stable, the researchers report.
But this mechanism didn't evolve to deal with modern technologies, such as alarm clocks or air travel. Messing with natural daily cycles can cause
jetlag, or more serious effects.
Shift work, for instance, has been linked to metabolic disorders such as diabetes, and even diseases like cancer.
"Shift work is now listed as a potential carcinogen by the World Health Organization," said study researcher Erik Herzog, a biologist at Washington University in St. Louis. By understanding how the brain's clock is wired, researchers could develop ways to improve the brain's ability to deal with these kinds of environmental perturbations, so they have fewer detrimental effects on our health, Herzog told LiveScience.
The brain's timing center is called the suprachiasmatic nucleus, or SCN. "Each cell is its own little timer," which works by turning on and off a set of "clock genes" that tell the cell to make proteins, Herzog explained. These genes operate on an approximately 24-hour cycle, known as a
circadian rhythm. These cycles are important for regulating metabolism, hormone release and sleep/waking cycles.
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