
© DARPA
I am going to do the hard work on a DARPA document so that you don't have to.The
document I am referring to is an Initial Announcement by the
Defense Advanced Research Projects Agency (DARPA) (
Biological Technologies Office (BTO)) for a funding opportunity in Generative
Optogenetics valued at $1.7M or $1.99M, depending on the research objective selected.
1 The announcement was posted on December 19, 2025 and Phase 1 of the project is likely well underway complete with a
workshop for interested parties.

© DARPA
So what this means is that DARPA is looking for smart people to design a protein complex that can synthesize DNA/RNA directly in living cells using optical signals. Now what the hell does that mean, you ask? I refer you to my article on optogenetics to find out, as a start.
To summarize (as I so succinctly did so in this
article), optogenetics is the introduction of genes into cells that don't naturally carry them, whereby the resulting proteins, once expressed,
can be controlled and monitored with light stimuli in neurons of living brains, heart muscle cells, and cultured cells.
Comment: