Your liver is the "brain of your body" and its healthy function is required for your ongoing well being. Your liver is potentially damaged by pollution, excess alcohol, medications, street drugs, internal "plumbing" problems, and excess food. For the first time, a process by which your liver can regenerate itself has been identified. As it turns out the endothelial cells
1 lining the circulatory system within your liver orchestrate the rejuvenation process.
© UnknownCross-section of liver showing sinusoidal endothelial cells
This is the first time scientists have ever documented a specific mechanism involved with liver rejuvenation. They hope to use the information to help individuals with liver injury or diseased livers. I think their discovery has immediate practical application value for you in terms of maintaining optimal liver function and health.
Endothelial cells are the weak link in the circulatory system. They form a thin layer, only one cell thick, which lines the insides of your arteries. They are crucial regulators of nutrient uptake from your circulation and instrumental in blood pressure regulation. When they are injured, the plaquing process is set in motion and increases potential for cardiovascular disease. In this context, the importance of endothelial cells has been understood for quite some time.
This new study proves that endothelial cells within your liver secrete signals that initiate and sustain the rejuvenation of your liver. They enable stem cells to form new liver cells and then coordinate the linking together of the liver cells to form new organ structure.
The problem is that endothelial cells are in contact with the contents of the blood.
The greater the number of stress chemicals, toxins, pollutants, antigens, junk food, and other irritants that come into contact with them, the greater the potential to damage these cells. This means that their ability to orchestrate rejuvenation would be compromised.
Furthermore, injured endothelial cells cannot be replaced by those next to them splitting and dividing so as to form a new layer. Rather, new endothelial cells must be produced in the bone marrow and travel to the liver (or anywhere else in the circulation) in order to fix the injured area. This means bone health must be maintained in order to have a supply of rejuvenating endothelial cells. This may be one key reason that bone health is associated with longevity (independent of the fracture issue).
The researchers also demonstrated that this mechanism of liver organ rejuvenation likely applies to all organs, although endothelial cell growth factors for each organ likely have different signals and these have not yet been figured out. However, the concept of preserving the health of your endothelial cells so as to aid general organ rejuvenation seems to be an emerging new fundamental principle of health.
In addition to bone health, this places a new emphasis on keeping your blood "cleaner" and your endothelial cells protected. This means the entire subject of detoxification is of immense importance. Nutrients that preserve the lining of the insides of your arteries including your endothelial cells. Top choices would include DHA, tocotrienol E, silymarin, taurine, and grape seed extract. However, there are many nutrients likely to help in one way or another.
The take home message is that you are more likely to be able to naturally rejuvenate your body organs (i.e., live longer and healthier) with cleaner blood, nourished endothelial cells lining your blood stream, and good bone health.
[1]
How the Liver Regenerates Nature 2.Bi-Sen Ding, Daniel J. Nolan, Jason M. Butler, Daylon James, Alexander O. Babazadeh, Zev Rosenwaks, Vivek Mittal, Hideki Kobayashi, Koji Shido, David Lyden, Thomas N. Sato, Sina Y. Rabbany, Shahin Rafii.
tissue in the human body both internal and external usually regenerates new cells to replace the old cells. This happens daily and it's DNA programmed. It's one of the reasons we stay alive for so long. Unfortunately the backbone of our biological functions the nervous system is the only system that doesn't follow this process namely you are born, live and die with the same nervous system. If for some reason it gets "hit" causing diseases like the bipolar disease, O.C.D. and even schizophrenia we can not intervene but only treat the symptoms. Bipolar disease is nothing new. Alexander the Great was a bi-pol, most German classical music composers were bi-pols like Mozart e.t.c. At the time they didn't have the proper medication and people suffering from these diseases died early in their lives. Ted Turner the former owner of CNN is a bi-pol and from what I've seen the man has done an excellent job all these years. Schizophrenia unfortunately is the worst damage the nervous system can be subjected to.The external part of the the nervous system molecules namely the membranes of the molecules have been corroded , thus you have MECHANICAL damage to the nervous system. There isn't much we can do in these cases than treat the symptoms again with the proper medication. That's about all I know.