As of Friday, April 11, 2008, at least 423 members of the U.S. military had died in Afghanistan, Pakistan and Uzbekistan as a result of the U.S. invasion of Afghanistan in late 2001, according to the Defense Department. The department last updated its figures April 5 at 10 a.m. EDT.

Of those, the military reports 290 were killed by hostile action.

Outside the Afghan region, the Defense Department reports 64 more members of the U.S. military died in support of Operation Enduring Freedom. Of those, two were the result of hostile action. The military lists these other locations as Guantanamo Bay Naval Base, Cuba; Djibouti; Eritrea; Ethiopia; Jordan; Kenya; Kyrgyzstan; Philippines; Seychelles; Sudan; Tajikistan; Turkey; and Yemen.

There were also four CIA officer deaths and one military civilian death.