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"In the past 24 hours, as a result of the strikes two ammunition warehouses, a plant producing ammunition and explosives, 30 firing positions and a machinery collection have been destroyed," the ministry's spokesman, Igor Konashenkov, said Tuesday.
The Su-24M, SU-25SM and SU-34 jets deployed for the mission have all returned to Russia's Khmeimim airbase in Latakia, he added.
The strikes hit targets associated with Islamic State and Al-Nusra in the provinces of Hama, Latakia, Damascus, Aleppo, Idlib and Deir al-Zor, Konashenkov said.
According to Konashenkov, Russian airstrikes destroyed "a command post and a communicating unit, which coordinated the actions of five armed groups" in Deir al-Zor. An ISIS mini-plant for the production of explosives and unguided missiles was destroyed by the strikes near the Hatla village in Deir al-Zor.
Near the village of Qastun in Idlib province, a large base housing a command post and a hidden ammunitions warehouse were targeted, he said.
Nine fortified areas, located in underground facilities in Hama province, were hit by the strikes as well, he added.
Meanwhile, on Tuesday Russia and the US signed a breakthrough agreement regulating the operations of both countries' air forces in Syria aimed at "preventing incidents and providing for aviation flights during operations." The agreement was hailed as a "positive step" by the Russian Defense Ministry.
Russia launched airstrikes targeting IS positions in Syria on September 30 following a formal request from President Bashar Assad.
Comment: Playtime is over! Russia to increase missions in Syria to 300 a day