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We know that over time chronic, imperceptible, low-level inflammation can contribute to serious, age-related diseases including heart disease, cancer and neurodegenerative conditions such as Alzheimer's and Parkinson's diseases. A new study from the University of Wisconsin shows that meditation can actually affect the genes that cause inflammation. Researchers measured the effects of a day of intensive mindfulness meditation in a group of experienced mediators and compared them with those of quiet, non-meditative activities by a group of untrained volunteers.

After eight hours of meditation, the researchers found altered levels of gene-regulating compounds and reduced activity levels of the pro-inflammatory genes in the experienced meditators. These changes were correlated with faster physical recovery from a stressful situation, the investigators explained. They reported that these findings are the first to show that mediation can inhibit production of proteins by some genes that cause inflammation and noted that at the study's outset there were no differences in the genes tested in both groups. They also reported that the positive changes were seen in genes that are the targets of anti-inflammatory and pain killing drugs.

Source

Perla Kaliman et al, "Rapid changes in histone deacetylases and inflammatory gene expression in expert meditators". Psychoneuroendocrinology, 40, 96 - 107