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Fri, 19 Apr 2019
The World for People who Think



Drug resistance? Primary malaria treatment fails to cure 4 patients in the UK

Malaria drug resistance
© Jim Young/Reuters
A key malaria treatment has failed for the first time, prompting scientists to fear the disease could be becoming resistant to the primary drugs used to counter it. The failure occurred in four patients being treated in the UK for an African strain of the mosquito-borne condition.

A team of medics from the London School of Hygiene and Tropical Medicine said it's still too early to say for sure that they had found a dangerous level of resistance, but called for further investigation. The results were reported in the Antimicrobial Agents and Chemotherapy Journal after being carried out in late 2016.

"It's remarkable there's been four apparent failures of treatment, there's not been any other published account [in the UK]," Dr Colin Sutherland told the BBC on Tuesday. Although the evidence is not yet conclusive, there are signs the strain is learning to fight back.

"It does feel like something is changing, but we're not yet in a crisis. It is an early sign and we need to take it quite seriously as it may be snowballing into something with greater impact," he said.

Bizarro Earth

Earth 'overdue' for magnetic pole reversal

Earth's Magnetic Field
© Shutterstock
The Earth's magnetic field, magnetic poles and geographic poles.
Earth's magnetic field may be about to reverse, which could have devastating consequences for humanity.

Scientists think that Earth is long "overdue" for a full magnetic reversal and have determined that the magnetic field's strength is already declining by 5 percent each century. This suggests that a fully reversal is highly probable within the next 2,000 years

Earth's magnetic field surrounds the planet and deflects charged particles from the sun away, protecting life from harmful radiation. There have been at least several hundred global magnetic reversals throughout Earth's history, during which the north and south magnetic poles swap. The most recent of these occurred 41,000 years ago.

During the reversal, the planet's magnetic field will weaken, allowing heightened levels of radiation on and above the Earth's surface.

The radiation spike would cause enormous problems for satellites, aviation, and the power grid. Such a reversal would be comparable to major geomagnetic storms from the sun.

The sun last produced such a storm that struck Earth during the summer of 1859, creating the largest geomagnetic storm on record. The storm was so powerful that it caused telegraph machines around the world to spark, shocking operators and setting papers ablaze. The event released the same amount of energy as 10 billion atomic bombs.

Researchers estimate that a similar event today would cause $600 billion to $2.6 trillion in damages to the U.S. alone. National Geographic found that a similar event today would destroy much of the internet, take down all satellite communications, and almost certainly knock out most of the global electrical grid. The Earth would only get about 20 hours of warning. Other estimates place the damage at roughly $40 billion a day.

A similar solar event occurred in 2012, but missed Earth.


Ice age cycles linked to orbital periods and sea ice

Ice Ages
© Jung-Eun Lee/Brown University
The Southern Hemisphere has a higher capacity to grow sea ice than the Northern Hemisphere, where continents block growth. New research shows that the expansion of Southern Hemisphere sea ice during certain periods in Earth’s orbital cycles can control the pace of the planet’s ice ages.
Providence, R.I. — Earth is currently in what climatologists call an interglacial period, a warm pulse between long, cold ice ages when glaciers dominate our planet's higher latitudes. For the past million years, these glacial-interglacial cycles have repeated roughly on a 100,000-year cycle. Now a team of Brown University researchers has a new explanation for that timing and why the cycle was different before a million years ago.

Using a set of computer simulations, the researchers show that two periodic variations in Earth's orbit combine on a 100,000-year cycle to cause an expansion of sea ice in the Southern Hemisphere. Compared to open ocean waters, that ice reflects more of the sun's rays back into space, substantially reducing the amount of solar energy the planet absorbs. As a result, global temperature cools.

"The 100,000-year pace of glacial-interglacial periods has been difficult to explain," said Jung-Eun Lee, an assistant professor in Brown's Department of Earth, Environmental and Planetary Studies and the study's lead author. "What we were able to show is the importance of sea ice in the Southern Hemisphere along with orbital forcings in setting the pace for the glacial-interglacial cycle."

The research is published in the journal Geophysical Research Letters.

Arrow Down

British court blocks Niger Delta pollution claims against Shell

Shell Pollution
Shell Development Company of Nigeria (SPDC) claims the main sources of pollution in Nigeria's Ogale and Bille communities are oil theft, pipeline sabotage and illegal refining.
A British court on Thursday blocked pollution claims against Anglo-Dutch energy giant Shell by more than 40,000 Niger Delta residents demanding action over decades of oil spills in the region.

Members of the Ogale and Bille communities had applied for the case to be heard in Britain, arguing they could not get justice in Nigeria. But the High Court in London said it did not have jurisdiction in the case.

"Our community is disappointed but not discouraged by this judgement," King Emere Godwin Bebe Okpabi, ruler of the Ogale Community, said in a statement.

"This decision has to be appealed, not just for Ogale but for many other people in the Niger Delta who will be shut out if this decision is allowed to stand.

"Shell is simply being asked to clean up its oil and to compensate the communities it has devastated," he said.

The firm's lawyer Peter Goldsmith told judge Peter Fraser during a hearing in November that the cases concerned "fundamentally Nigerian issues", and should not be heard in London. However, Daniel Leader from legal firm Leigh Day, representing the claimants, responded that the spills had "blighted the lives of the thousands".

He said they had "no choice" other than to seek legal redress in London. Goldsmith also argued that the case involves Shell's Nigerian subsidiary SPDC, which runs a joint venture with the Nigerian government.

He claimed that the case was aimed at establishing the High Court's jurisdiction over SPDC, opening the door for further claims.


Researchers: Countries 'grossly underprepared' for infectious disease outbreaks

Ebola virus
This National Institute of Allergy and Infectious Diseases (NIAID) image taken on August 12, 2014 by a digitally-colorized scanning electron micrograph (SEM) depicts a single filamentous Ebola virus particle.
Review of the response to the Ebola virus points to the world not being prepared for infectious disease outbreaks

An analysis of reports on the response to the Ebola virus outbreak in West Africa has researchers sounding the alarm about worldwide infectious disease outbreak preparedness.

Suerie Moon of the Graduate Institute of International and Development Studies in Geneva, Switzerland, and a team of researchers examined seven post-Ebola reports.

They identified critical problems and made recommendations including strengthening compliance with the International Health Regulations, or IHR, improving outbreak-related research and information sharing, reforming the World Health Organization, or WHO, and broadening the humanitarian response system.

"We found remarkable consensus on what went wrong with the Ebola response and what we need to do to address the deficiencies," study authors said in a press release. "Yet not nearly enough has been done. Ebola, and more recently Zika and yellow fever, have demonstrated that we do not yet have a reliable or robust global system for preventing, detecting and responding to disease outbreaks."

The team urged the world "to mobilize greater resources and put in place monitoring and accountability mechanisms to ensure we are better prepared for the next pandemic."

Microscope 1

Rare Seoul rat virus sickens 6 people in Illinois, 2 in Wisconsin

Girl with pet rat
© Diez, O./Global Look Press
The Centers for Disease Control and Prevention said eight people became ill after contracting a rare rat virus in Illinois and Wisconsin. The one unifying factor between all the infected people was their contact with pet rats.

Two of the people who fell ill worked in ratteries in Wisconsin, with one going to hospital. People are infected when they breathe in dust contaminated with rodent droppings or urine.

"A home-based rodent breeder in Wisconsin was hospitalized in December 2016 with fever, headache and other symptoms," the CDC said in a statement.

"Symptoms may include fever, severe headache, back and abdominal pain, chills, blurred vision, redness of the eyes, or rash. In rare cases, infection can also lead to acute renal disease," the CDC added. "However, not all people infected with the virus experience symptoms. Most people infected with Seoul virus recover."

Both breeders tested positive for Seoul virus, a member of the Hantavirus family of rodent-borne viruses, according to the CDC. Others fell ill who purchased pet rats from animal suppliers in Wisconsin and Illinois. All the people have recovered.


Ancient tree rings suggest sunspot cycles similar to the one observed in more modern times

The Sun
The Sun by the Atmospheric Imaging Assembly of NASA's Solar Dynamics Observatory.
A pair of researchers affiliated with the Natural History Museum in Chemnitz and Technische Universität Bergakademie Freiberg, both in Germany, has found evidence in ancient tree rings of a solar sunspot cycle millions of years ago similar to the one observed in more modern times. In their paper published in the journal Geology, Ludwig Luthardt and Ronny Rößler describe how they gathered an assortment of petrified tree samples from a region in Germany and used them to count sunspot cycles.

Scientists know that the sun undergoes a sunspot cycle of approximately 11 years—some spots appear, grow cooler and then slowly move toward the equator and eventually disappear—the changes to the sun spots cause changes to the brightness level of the sun—as the level waxes and wanes, plants here on Earth respond, growing more or less in a given year—this can be seen in the width of tree rings. In this new effort, the researchers gathered petrified tree samples from a region of Germany that was covered by lava during a volcanic eruption approximately 290 million years ago (during the Permian period), offering a historical record of sun activity.

The research pair obtained 43 petrified tree specimens (tree-trunk slices) and report that they were able to count 1,917 rings which were preserved well enough to allow for observation under a microscope. Because the trees had all died at the same time, the researchers were able to establish a baseline between them which allowed for comparing tree ring growth between samples over the same time periods—which covered 79 years. Doing so, they report, revealed very clearly a cycle of growth similar to that seen in modern trees, though in this case, it was slightly different. Today the cycle is an average of 11.2 years, back then it was 10.6—close enough, the researchers suggest, to conclude that the sun has been behaving very predictably for at least 290 million years.

It should be noted that not everyone agrees with the theory that sunspot activity leaves such a clear record in tree rings—other factors might be involved such as general global temperature, weather patterns or even outbreaks of insect populations.

More information: Ludwig Luthardt et al. Fossil forest reveals sunspot activity in the early Permian, Geology(2017)


Convenient excuse? Race to make vaccine for the plague amid fears 'terrorists could be turning it into a weapon' to wipe out millions

black plague
Scientists are racing to create a vaccine for the plague - before terrorists develop the deadly disease into a weapon. The illness is largely seen as a thing of the past, best known for wiping out a third of Europe's population during the Black Death of the 1300s. But experts warn it is one of the most likely candidates for a bioweapon - especially given the increasing rate of antibiotic resistance.

Lead researcher Dr Ashok Chopra, whose research is being backed by the Department of Defense, warns the scenario is a more realistic prospect than we think. 'Terrorists can easily grow the bacteria and make the strains resistant to antibiotics,' Dr Chopra, a microbiologist and immunologist at the University of Texas microbiologist, told Daily Mail Online.

'The pneumonic plague is very contagious and very hard to treat. It could kill millions. 'Think of the Black Death of the 14th century. It is not unrealistic that we would experience the same number of mass casualties. It could be quite devastating.'

There are three strains of the plague - pneumonic, bubonic, and septicemic - all caused by bacteria called Yersinia pestis. The most common type is the bubonic plague, typically found on animals and transmitted to humans via fleas.

It was the bubonic plague that caused the Black Death, as well as America's first outbreak in 1900 when infected animals were imported from Asia to San Francisco. However, the pneumonic plague, which is airborne, is fatal almost 100 percent of the time.

Comment: Although a horrible disease, Bubonic plague is not the infamous Black Death that killed half of Europe's population in the Middle Ages, according to recent research. The latter was likely to be caused in part by pathogens brought to Earth by comets. See this book review for more information:

New Light on the Black Death: The Cosmic Connection

Comment: For an even more in-depth study of cosmic forces at work, read Pierre Lescaudron with Laura Knight-Jadczyk's Earth Changes and the Human-Cosmic Connection


Unknown virus causing migratory pain, black urine reported in Bahia, Brazil

Lab worker
© 24 Horas News
Nine people have been affected by an unknown virus which has caused people to develop muscle pain and discharge a black urine.

This was confirmed by Dr. Gubbio Soares, a researcher at the virology laboratory at the Federal University of Bahia (UFBA). He stated that his research team have been able to determine that the ailment was caused by a virus, but haven't been able to identify what virus it is.

The team will require at least 15 days to figure out the origin of the virus. "We already know that it is a virus that causes the disease, but we have not yet determined which type. "We need about 10 to 15 days to make this identification."

As at the time of this report, only the transmission mode has been identified according to Soares who believes this is done orally. Another symptom of the virus is an increment in the body's CPK enzyme.

Addressing the effect of the enzyme on a patient who had the virus, Soares thinks such a person should admitted at the hospital until the urine returns to normal. "He had a patient with CPK index of 100 thousand units per liter of blood, while the normal one is 200 units per liter,"

"Because of the risk of kidney failure, patients should be hospitalized until the urine returns to normal."

Comment: The latest from Pravda.ru reports the following:
The first cases were reported between December 2 and December 10 in the northern coastal área of the State of Bahia in central Brazil - sudden intense pain in the cervical region, then in the limbs and torso, back, moving down to the legs, and passing black urine. In all cases CPK muscular enzymes suffer significant alterations. Renal deficiency was detected in at least one patient and the first medical reports suggested a vírus which was contracted through contact with droplets of saliva or physical contact...

...The local newspaper Correio24horas reports no less than 18 cases, 16 in the capital, Salvador de Bahia. The other cases were registered in the city of Valença, in the Southern part of the State of Bahia. The cases in Salvador are all linked to the same source - the victims came from three families who ate a moqueca, or stew, made with a Bull's Eye (Olho de Bói, or Arabaiana) bought from fishermen on the beach of Genipabu, in Guarajuba. The fact that there are other cases registered elsewhere may point towards the existence of a vírus.


Over 2,000 deer reported dead in South Dakota disease outbreak

South Dakota Game, Fish and Parks Department issued more deer licenses this year than it did last year. Due to an outbreak fear of deer numbers being down

South Dakota Game, Fish and Parks Department issued more deer licenses this year than it did last year. Due to an outbreak fear of deer numbers being down this year
Epizootic Hemorrhagic Disease, a viral disease that killed more than 3,700 deer in 2012, has impacted the population this year, with more than 2,000 deer found dead in 23 counties, The Mitchell Daily Republic reported. The heaviest losses have been in Brule, Aurora and Beadle Counties. In Beadle County, 209 deer were found dead and in Brule County, 206 deer were found dead.

Hughes and Sully Counties were not spared. A total of 140 deer were found dead in Hughes County, while 85 were found in Sully County, said Andy Lindbloom, senior big game biologist.

"We definitely got closer to 2012 than we would have liked," Lindbloom said.

The state issued about 29,000 resident licenses this year. It also issued about 42,000 individual tags, a 33 percent increase from last year.

Lindbloom said that about 1,500 licenses were returned as of Monday afternoon. Hunters with licenses for the muzzleloader deer season have until the end of this week to send their tags in for a refund.