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Four people pleaded guilty Thursday to breaking federal law by marketing the drug Loprox to Kansas doctors as a diaper-rash treatment, the U.S. Attorney's Office said.
Scientists have made a significant discovery that clarifies a previously poorly understood key event in the progression of breast cancer. The research, published by Cell Press in the May issue of the journal Cancer Cell, highlights the importance of the microenvironment in regulating breast tumor progression and suggests that it may be highly beneficial to consider therapies that do not focus solely on the tumor cells but are also targeted to the surrounding tissues.
Progression of breast cancer begins with abnormal epithelial proliferation that progresses into localized carcinoma, called ductal carcinoma in situ (DCIS); invasive carcinoma; and eventually, metastatic disease. DCIS is believed to be a precursor to invasive ductal carcinoma, but comprehensive molecular profiling studies comparing DCIS and invasive ductal carcinomas have not yielded tumor-stage-specific genetic signatures. "These studies have focused mainly on the tumor epithelial cells and have not explored the role of the microenvironment in tumor expression," says lead study author Dr. Kornelia Polyak from the Dana-Farber Cancer Institute in Boston.
Progression of breast cancer begins with abnormal epithelial proliferation that progresses into localized carcinoma, called ductal carcinoma in situ (DCIS); invasive carcinoma; and eventually, metastatic disease. DCIS is believed to be a precursor to invasive ductal carcinoma, but comprehensive molecular profiling studies comparing DCIS and invasive ductal carcinomas have not yielded tumor-stage-specific genetic signatures. "These studies have focused mainly on the tumor epithelial cells and have not explored the role of the microenvironment in tumor expression," says lead study author Dr. Kornelia Polyak from the Dana-Farber Cancer Institute in Boston.
Parents of children with autism were roughly twice as likely to have been hospitalized for a mental disorder, such as schizophrenia, than parents of other children, according to an analysis of Swedish birth and hospital records by a University of North Carolina at Chapel Hill researcher and colleagues in the U.S. and Europe.
The study, "Parental psychiatric disorders associated with autism spectrum disorders in the offspring," appears in the May 5, 2008, issue of the journal Pediatrics.
"We are trying to determine whether autism is more common among families with other psychiatric disorders. Establishing an association between autism and other psychiatric disorders might enable future investigators to better focus on genetic and environmental factors that might be shared among these disorders," said study author Julie Daniels, Ph.D., an assistant professor in the UNC School of Public Health's epidemiology and maternal and child health departments.
The study, "Parental psychiatric disorders associated with autism spectrum disorders in the offspring," appears in the May 5, 2008, issue of the journal Pediatrics.
"We are trying to determine whether autism is more common among families with other psychiatric disorders. Establishing an association between autism and other psychiatric disorders might enable future investigators to better focus on genetic and environmental factors that might be shared among these disorders," said study author Julie Daniels, Ph.D., an assistant professor in the UNC School of Public Health's epidemiology and maternal and child health departments.
New disaster proposal could legally protect physicians.
In an unprecedented initiative, US and Canadian experts have developed a comprehensive framework to optimize and manage critical care resources during times of pandemic outbreaks or other mass critical care disasters. The new proposal suggests legally protecting clinicians who follow accepted protocols for the allocation of scarce resources when providing care during mass critical care events. The framework represents a major step forward to uniformly deliver sufficient critical care during catastrophes and maximize the number of victims who have access to potential life-saving interventions.
"Most countries, including the United States, have insufficient critical care resources to provide timely, usual care for a surge of critically ill and injured victims," said Asha Devereaux, MD, FCCP, Task Force for Mass Critical Care. "If a mass casualty critical care event occurred tomorrow, many people with clinical conditions that are survivable under usual health-care system circumstances may have to forgo life-sustaining interventions due to deficiencies in supply, staffing, or space." As a result, the Task Force for Mass Critical Care developed an emergency mass critical care (EMCC) framework for hospitals and public health authorities aimed to maximize effective critical care surge capacity.
In an unprecedented initiative, US and Canadian experts have developed a comprehensive framework to optimize and manage critical care resources during times of pandemic outbreaks or other mass critical care disasters. The new proposal suggests legally protecting clinicians who follow accepted protocols for the allocation of scarce resources when providing care during mass critical care events. The framework represents a major step forward to uniformly deliver sufficient critical care during catastrophes and maximize the number of victims who have access to potential life-saving interventions.
"Most countries, including the United States, have insufficient critical care resources to provide timely, usual care for a surge of critically ill and injured victims," said Asha Devereaux, MD, FCCP, Task Force for Mass Critical Care. "If a mass casualty critical care event occurred tomorrow, many people with clinical conditions that are survivable under usual health-care system circumstances may have to forgo life-sustaining interventions due to deficiencies in supply, staffing, or space." As a result, the Task Force for Mass Critical Care developed an emergency mass critical care (EMCC) framework for hospitals and public health authorities aimed to maximize effective critical care surge capacity.
WASHINGTON - Federal drug regulators believe that a contaminant detected in a crucial blood thinner that has caused 81 deaths was added deliberately, something the Food and Drug Administration has only hinted at previously.
"F.D.A.'s working hypothesis is that this was intentional contamination, but this is not yet proven," Dr. Janet Woodcock, director of the Food and Drug Administration's drug center, told the House Subcommittee on Oversight and Investigations in written testimony given Tuesday.
A third of the material in some batches of the thinner heparin were contaminants, "and it does strain one's credulity to suggest that might have been done accidentally," Dr. Woodcock said.
"F.D.A.'s working hypothesis is that this was intentional contamination, but this is not yet proven," Dr. Janet Woodcock, director of the Food and Drug Administration's drug center, told the House Subcommittee on Oversight and Investigations in written testimony given Tuesday.
A third of the material in some batches of the thinner heparin were contaminants, "and it does strain one's credulity to suggest that might have been done accidentally," Dr. Woodcock said.
Remember a couple of years ago how the FDA warned Americans not to buy prescription drugs from Canada because they might be "contaminated by terrorists?" I'm not making that up: That was the official announcement of an FDA spokesperson, and it was part of their fear strategy for enforcing a monopoly on U.S. consumers so that Big Pharma could continue engaging in rampant price fixing.
The implication in that warning is that drugs purchased in the United States are therefore safer, correct? What the FDA didn't tell anyone, however, is that most pharmaceuticals purchased in the United States are manufactured outside the U.S.; many from China or Puerto Rico. So they're not even made in the U.S. anyway, and drug companies are simply importing them from other countries just like a consumer might do if she drove across the border and bought her medications in Canada or Mexico.
The implication in that warning is that drugs purchased in the United States are therefore safer, correct? What the FDA didn't tell anyone, however, is that most pharmaceuticals purchased in the United States are manufactured outside the U.S.; many from China or Puerto Rico. So they're not even made in the U.S. anyway, and drug companies are simply importing them from other countries just like a consumer might do if she drove across the border and bought her medications in Canada or Mexico.
DALLAS - "I guess I'm getting emotional right now because I don't want to be here," Christine Gianadda said. "I want my kids to be in school having friends."
But that's not an option for her 9 year old son, Gordon.
He was diagnosed with Asperger Syndrome, a regressive form of autism, when he was 13 months old.
"I mean we'd put him down for a nap and he woke up screaming, beating his head, lost all language," she said.
Parents gathered in front of the federal courthouse in Dallas to show there's a link between mercury emissions from coal fire plants and autism.
But that's not an option for her 9 year old son, Gordon.
He was diagnosed with Asperger Syndrome, a regressive form of autism, when he was 13 months old.
"I mean we'd put him down for a nap and he woke up screaming, beating his head, lost all language," she said.
Parents gathered in front of the federal courthouse in Dallas to show there's a link between mercury emissions from coal fire plants and autism.
In order to establish an exemption to mandatory vaccines, the Philosophical Exemption to Immunizations Act recently was introduced in the New York State Assembly. Currently, there are 18 states that give parents this right, while most other states offer only religious or medical exemptions.
Phrases such as "survival of the fittest" and "every man for himself" may seem to accentuate the presence of political and social competition in American culture; however, there obviously are similar instances of inter- and intra-group conflict across almost all known organisms. So what makes competition so prevalent for life and why does it sometimes seem to be preferred over cooperation?
Comment: Perhaps because we're ruled by psychopaths, who have instituted a psychopathic system - where lack of conscience is condoned, if not glorified. Perhaps also because our own innate insecurities are taken advantage of - and the truth of things is consistently hidden by our political masters, in the state apparatus, in religion, in business, in education. For more on this, see here.
WASHINGTON - A New York company is voluntarily recalling about 286,000 pounds (129,700 kg) of fresh and frozen meat and poultry products that may be contaminated with bacteria, U.S. agriculture officials said on Saturday.
The products produced by Gourmet Boutique LLC of Jamaica, New York, were sent to food service and retail establishments nationwide, a U.S. Department of Agriculture statement said.
The meat may be contaminated with Listeria monocyotogenes bacteria, which can cause a rare but potentially fatal disease known as listeriosis, the USDA said. Infants, the elderly, people with HIV and patients undergoing chemotherapy are among those at risk for the disease.
The products produced by Gourmet Boutique LLC of Jamaica, New York, were sent to food service and retail establishments nationwide, a U.S. Department of Agriculture statement said.
The meat may be contaminated with Listeria monocyotogenes bacteria, which can cause a rare but potentially fatal disease known as listeriosis, the USDA said. Infants, the elderly, people with HIV and patients undergoing chemotherapy are among those at risk for the disease.
Comment: The damage industrial emissions do is covered up, the damage that poisons in our food, water, household products and medicines, is suppressed; but for GOD'S sake! do NOT Smoke!
You really think they are doing that for your benefit?