The story of Zantac, the common heartburn medicine, is both awful and good - it's awful because one of the most common drugs on the market may have been causing cancers for forty years. It's good only because the story is finally being told and 70,000 people are suing GlaxoSmithKline (GSK). The "good" here is the hope that some justice might finally be done, and because the public might find out just how ghastly the industrial pharma octopus really is, and how welded it is in the system.
It's time to burn down the unholy empire of Big Pharma and Big Government and start again.
This is not a case of one bad egg in the system, it's the story of a system that virtually creates bad eggs
Glaxo was a little company in the 70s that took one of the most popular drugs on the market, Tagamet, tweaked it enough to patent a "better version", then aggressively out-marketed it, and eventually bought out the companies that made Tagamet to become the $70 billion GlaxoSmithKline giant.
"By 1989, Zantac was worth $2 billion. It accounted for half of Glaxo's sales and 53% of the market for prescription ulcer remedies."But the common heartburn drug Zantac, or ranitidine, which drove their profits — also broke down into NDMA which is a known carcinogen, and there were warnings of this in 1981 and 1982, but it wasn't until September 2019 that an independent lab tested for NDMA and found it in every sample and at alarming levels. By April 2020 the FDA forced every manufacturer to stop producing and selling the drug altogether. Now, the court cases have started.
Most of the Bloomberg story — which is worth reading in full — focuses on just how badly behaved GlaxoSmithKline have been by hiding the early data for forty long years. But GSK also chose not to do more tests when it should have; it did not try to transport and store the drug in ways the reduced the contamination, and it did not advise the public to take the tablets outside meals. There is no sense that customer health mattered.
To me the bigger question that is never asked, is why drugs like this are not tested by publicly funded groups before they get approval to be rolled out en masse? The tests that were finally done in 2019 are not two-year studies involving thousands of people, they are just lab tests for contamination. What is the point of all the public health funding, the regulatory agencies, and public universities if they aren't used to defend the public?
If the FDA has the legal power to approve drugs or ban them, shouldn't it also bear the responsibility when it gets that wrong?
Under legal cross examination the director of research and development admitted they had known for almost 40 years that ranitidine could degrade under conditions of high temperature and moisture ... .
Comment: It doesn't appear to be an outbreak of great concern yet, however it's worth noting.
See also: Did West Africa's ebola outbreak of 2014 have a lab origin? - And the critical covid connections