A compound found in grape seed extract reduces plaque formation and resulting cognitive impairment in an animal model of Alzheimer's disease, new research shows.
The study appears in the June 18 issue of The Journal of Neuroscience. Lead study author Giulio Pasinetti, MD, PhD, of Mount Sinai School of Medicine and colleagues found that the grape seed extract prevents amyloid beta accumulation in cells, suggesting that it may block the formation of plaques. In Alzheimer's disease, amyloid beta accumulates to form toxic plaques that disrupt normal brain function.
Health & Wellness
Washington - A House subcommittee voted Thursday to subpoena the records of nine private laboratories involved in food testing as part of a congressional investigation into allegations that some companies have withheld information on tainted food from federal regulators.
The subcommittee in May asked 10 labs for records dating back to 2002, but just one, in Miami, complied. The other labs, according to the subcommittee, refused to turn over records, arguing that the documents belong to their clients, food importing companies.
The subcommittee in May asked 10 labs for records dating back to 2002, but just one, in Miami, complied. The other labs, according to the subcommittee, refused to turn over records, arguing that the documents belong to their clients, food importing companies.
A Dutch woman who was the oldest person in the world when she died aged 115 appeared sharp right up to the end, joking that pickled herring was the secret to her longevity.
The government is testing drugs with severe side effects like psychosis and suicidal behavior on hundreds of military veterans, using small cash payments to attract patients into medical experiments that often target distressed soldiers returning from Iraq and Afghanistan, a Washington Times/ABC News investigation has found.
In one such experiment involving the controversial anti-smoking drug Chantix, the Department of Veterans Affairs (VA) took three months to alert its patients about severe mental side effects. The warning did not arrive until after one of the veterans taking the drug had suffered a psychotic episode that ended in a near lethal confrontation with police.
In one such experiment involving the controversial anti-smoking drug Chantix, the Department of Veterans Affairs (VA) took three months to alert its patients about severe mental side effects. The warning did not arrive until after one of the veterans taking the drug had suffered a psychotic episode that ended in a near lethal confrontation with police.
|
| ©Washington Times |
| Iraq war veteran James Elliott smokes on his porch in Silver Spring as he talks about his experiences in war and dealing with post-traumatic stress disorder. Mr. Elliott suffered a psychotic episode while taking the anti-smoking drug Chantix. |
Comprehensive lifestyle changes including a better diet and more exercise can lead not only to a better physique, but also to swift and dramatic changes at the genetic level, U.S. researchers said on Monday.
Would you take a wonder drug that offered to free you from decades of nicotine addiction? Even if other users reported sinister psychological side effects? For Derek de Koff, the answer was easy: after 12 years as a smoker, he was ready to try anything to kick the habit. Or so he thought...
I'd heard about Chantix, a relatively new drug from Pfizer that blocks nicotine from attaching to your brain receptors. That way, you stop receiving any pleasure from cigarettes at all. The drug, snuggling up to those receptors the same way nicotine does, reduces withdrawal cravings and unleashes a happy little wash of dopamine to boot. Wonderful things they can do nowadays.
My doctor wished me luck as he wrote out the prescription, telling me it was the single most important decision I'd ever make. I had the medication that night, 35 minutes after dropping into a pharmacy. While waiting, I gleefully chain-smoked Parliament Lights. One of Chantix's big perks is that you can smoke for the first seven days you're on it (most people take it for 12 weeks) more than enough time, I thought, to say goodbye to an old friend.
I'd heard about Chantix, a relatively new drug from Pfizer that blocks nicotine from attaching to your brain receptors. That way, you stop receiving any pleasure from cigarettes at all. The drug, snuggling up to those receptors the same way nicotine does, reduces withdrawal cravings and unleashes a happy little wash of dopamine to boot. Wonderful things they can do nowadays.
My doctor wished me luck as he wrote out the prescription, telling me it was the single most important decision I'd ever make. I had the medication that night, 35 minutes after dropping into a pharmacy. While waiting, I gleefully chain-smoked Parliament Lights. One of Chantix's big perks is that you can smoke for the first seven days you're on it (most people take it for 12 weeks) more than enough time, I thought, to say goodbye to an old friend.
A fruit-flavoured sugar pill which parents can use to soothe childhood aches and pains has been criticised. The pills are already on sale in the US, costing $6 for a bottle of 50.
They harness the "placebo effect", which makes some people feel better because they falsely believe they have had medicine. One UK scientist said it could make children rely on pills later in life, and another accused the makers of "medicalising love".
They harness the "placebo effect", which makes some people feel better because they falsely believe they have had medicine. One UK scientist said it could make children rely on pills later in life, and another accused the makers of "medicalising love".
At least 50% of recent onset rheumatoid arthritis patients achieve remission (a state free of signs and symptoms) within 36 weeks when following a systematic approach of step-up DMARD treatment in combination with tight control, according to results of a study presented June 11 at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France. Results of this study indicate that achieving remission is not only possible during clinical trials but can be a realistic goal of standard clinical care.
New research at UT Southwestern Medical Center may explain why some people who are stressed or depressed overeat. While levels of the so-called "hunger hormone" ghrelin are known to increase when a person doesn't eat, findings by UT Southwestern scientists suggest that the hormone might also help defend against symptoms of stress-induced depression and anxiety.
"Our findings in mice suggest that chronic stress causes ghrelin levels to go up and that behaviors associated with depression and anxiety decrease when ghrelin levels rise. An unfortunate side effect, however, is increased food intake and body weight," said Dr. Jeffrey Zigman, assistant professor of internal medicine and psychiatry at UT Southwestern and senior author of a study appearing online today and in a future print edition of Nature Neuroscience.
|
| ©UT Southwestern Medical Center |
| While levels of the so-called "hunger hormone" ghrelin are known to increase when a person doesn't eat, new findings by Drs. Jeffrey Zigman (left) and Michael Lutter suggest that the hormone might also help defend against symptoms of stress-induced depression and anxiety. |
"Our findings in mice suggest that chronic stress causes ghrelin levels to go up and that behaviors associated with depression and anxiety decrease when ghrelin levels rise. An unfortunate side effect, however, is increased food intake and body weight," said Dr. Jeffrey Zigman, assistant professor of internal medicine and psychiatry at UT Southwestern and senior author of a study appearing online today and in a future print edition of Nature Neuroscience.
Comment: See:Mind over matter: Anti-smoking drug linked to suicide and The Brain Trauma Vets.