After an unknown disease claimed 140 lives in four weeks in Kanpur Dehat district, Uttar Pradesh health authorities now face the challenge of another mysterious malady that has claimed 28 lives in the Rampur district.
According to official records, in the last 30 days about 28 people have died of the unknown disease in Rampur district, over 200 km from here.
Health & Wellness
Researchers from the University of Pennsylvania School of Medicine have identified a key step in the formation - and suppression - of esophageal cancers and perhaps carcinomas of the breast, head, and neck. By studying human tissue samples, they found that Fbx4, a naturally occurring enzyme, plays a key role in stopping production of another protein called Cyclin D1, which is thought to contribute to the early stages of cancer development.
When mutations block production of Fbx4, Cyclin D1 is not broken down, and subsequently contributes to cancer's advance. Fbx4 acts like a bouncer, stopping trouble before it starts by breaking down Cyclin D1 before it can affect the body.
"Cyclin D1 was identified nearly 20 years ago and after that, it became apparent that it was overexpressed in a high percentage of tumors," says J. Alan Diehl, PhD, Associate Professor of Cancer Biology at the University of Pennsylvania's Abramson Family Cancer Research Institute. "But its expression didn't correlate to mutations within Cyclin D1, so we were looking for a protein that regulates accumulation. That's Fbx4."
When mutations block production of Fbx4, Cyclin D1 is not broken down, and subsequently contributes to cancer's advance. Fbx4 acts like a bouncer, stopping trouble before it starts by breaking down Cyclin D1 before it can affect the body.
"Cyclin D1 was identified nearly 20 years ago and after that, it became apparent that it was overexpressed in a high percentage of tumors," says J. Alan Diehl, PhD, Associate Professor of Cancer Biology at the University of Pennsylvania's Abramson Family Cancer Research Institute. "But its expression didn't correlate to mutations within Cyclin D1, so we were looking for a protein that regulates accumulation. That's Fbx4."
The University of Southampton is launching the world's largest-ever study of near-death experiences this week.
The AWARE (AWAreness during REsuscitation) study is to be launched by the Human Consciousness Project of the University of Southampton - an international collaboration of scientists and physicians who have joined forces to study the human brain, consciousness and clinical death.
The study is led by Dr Sam Parnia, an expert in the field of consciousness during clinical death, together with Dr Peter Fenwick and Professors Stephen Holgate and Robert Peveler of the University of Southampton. Following a successful 18-month pilot phase at selected hospitals in the UK, the study is now being expanded to include other centres within the UK, mainland Europe and North America.
"Contrary to popular perception," Dr Parnia explains, "death is not a specific moment. It is a process that begins when the heart stops beating, the lungs stop working and the brain ceases functioning - a medical condition termed cardiac arrest, which from a biological viewpoint is synonymous with clinical death.
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| ©iStockphoto/Felix Möckel |
| Contrary to popular perception, death is not a specific moment, scientists say. It is a process that begins when the heart stops beating, the lungs stop working and the brain ceases functioning. |
The AWARE (AWAreness during REsuscitation) study is to be launched by the Human Consciousness Project of the University of Southampton - an international collaboration of scientists and physicians who have joined forces to study the human brain, consciousness and clinical death.
The study is led by Dr Sam Parnia, an expert in the field of consciousness during clinical death, together with Dr Peter Fenwick and Professors Stephen Holgate and Robert Peveler of the University of Southampton. Following a successful 18-month pilot phase at selected hospitals in the UK, the study is now being expanded to include other centres within the UK, mainland Europe and North America.
"Contrary to popular perception," Dr Parnia explains, "death is not a specific moment. It is a process that begins when the heart stops beating, the lungs stop working and the brain ceases functioning - a medical condition termed cardiac arrest, which from a biological viewpoint is synonymous with clinical death.
While compulsive gambling is only beginning to be addressed by mental health professionals, they must now face a new affliction: Internet addiction.
"The problem isn't widespread but we know of serious cases in which teenagers don't leave the house, don't have interpersonal relationships, and have been isolated in front of their computer screen for the past two or three years, and only speak in the language of the characters they play with in network video games," says Louise Nadeau, a professor at the Université de Montréal's Department of Psychology.
"In a few years we'll have couples in therapy because the Internet will have become their main occupation."
Nadeau is director of the new university institute on addiction. It was created last year by the Ministère de la Santé et des Services sociaux. The mandate of the institute is to conduct epidemiological studies on addiction, evaluate the services available to patients, guarantee state-of-the-art practices, and document new forms of addiction.
"The problem isn't widespread but we know of serious cases in which teenagers don't leave the house, don't have interpersonal relationships, and have been isolated in front of their computer screen for the past two or three years, and only speak in the language of the characters they play with in network video games," says Louise Nadeau, a professor at the Université de Montréal's Department of Psychology.
"In a few years we'll have couples in therapy because the Internet will have become their main occupation."
Nadeau is director of the new university institute on addiction. It was created last year by the Ministère de la Santé et des Services sociaux. The mandate of the institute is to conduct epidemiological studies on addiction, evaluate the services available to patients, guarantee state-of-the-art practices, and document new forms of addiction.
Mice given quercetin, a naturally occurring substance found in fruits and vegetables, were less likely to contract the flu, according to a study published by The American Physiological Society. The study also found that stressful exercise increased the susceptibility of mice to the flu, but quercetin canceled out that negative effect.
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| ©iStockphoto/Jack Puccio |
| Quercetin, a close chemical relative of resveratrol, is present in a variety of fruits and vegetables, including red onions, grapes, blueberries, tea, broccoli and red wine. It appears to protect against the flu. |
It appears that mind over matter may be the key to achieving sexual satisfaction, according to one study.
Researchers from the University of Southern California and Yale University reached this conclusion after studying the "satisfying" sex lives of cervical cancer survivors who had both ovaries removed.
Removing the ovaries, according to background offered in a study published in the July issue of the Journal of Women's Health, reduces or eliminates circulation of the hormone testosterone, which plays a factor in both male and female sexuality.
Researchers from the University of Southern California and Yale University reached this conclusion after studying the "satisfying" sex lives of cervical cancer survivors who had both ovaries removed.
Removing the ovaries, according to background offered in a study published in the July issue of the Journal of Women's Health, reduces or eliminates circulation of the hormone testosterone, which plays a factor in both male and female sexuality.
WASHINGTON - Having higher vitamin B12 levels may protect against brain shrinkage in elderly people, according to a study published on Monday.
The researchers called their findings striking, but said more information is needed before recommending that people take vitamin B12 supplements to guard against the loss of brain volume and possibly prevent declines in thinking and memory
The researchers called their findings striking, but said more information is needed before recommending that people take vitamin B12 supplements to guard against the loss of brain volume and possibly prevent declines in thinking and memory
"Californication" star David Duchovny made headlines for voluntarily entering rehab last week. But it wasn't for drugs or alcohol. It was for another dependency, one that affects millions of Americans but is seldom discussed: sex addiction.
Research engineers and sleep medicine specialists from two Michigan universities have joined technical and clinical hands to put innovative quantitative analysis, signal-processing technology and computer algorithms to work in the sleep lab. One of their recent findings is that a new approach to analyzing sleep fragmentation appears to distinguish fibromyalgia patients from healthy controls.
Joseph W. Burns, a research scientist and engineer at the Michigan Tech Research Institute (MTRI); Ronald D. Chervin, director of the University of Michigan's Michael S. Aldrich Sleep Disorders Laboratory; and Leslie Crofford, director of the Center for the Advancement of Women's Health at the University of Kentucky, report the results of their study in the current issue of the journal Sleep Medicine.
MTRI, a freestanding research institute acquired by Michigan Tech in 2006 and based in Ann Arbor, specializes in remote sensors that collect data, and in signal processing, using algorithms or computer programs to analyze and correlate the information the sensors gather. MTRI has developed an ongoing collaboration with the University of Michigan's sleep laboratory, one of the nation's leading clinical and research centers specializing in sleep medicine.
Joseph W. Burns, a research scientist and engineer at the Michigan Tech Research Institute (MTRI); Ronald D. Chervin, director of the University of Michigan's Michael S. Aldrich Sleep Disorders Laboratory; and Leslie Crofford, director of the Center for the Advancement of Women's Health at the University of Kentucky, report the results of their study in the current issue of the journal Sleep Medicine.
MTRI, a freestanding research institute acquired by Michigan Tech in 2006 and based in Ann Arbor, specializes in remote sensors that collect data, and in signal processing, using algorithms or computer programs to analyze and correlate the information the sensors gather. MTRI has developed an ongoing collaboration with the University of Michigan's sleep laboratory, one of the nation's leading clinical and research centers specializing in sleep medicine.
Colonies of hospital superbugs can make poisons similar to those found in rattlesnake venom to attack our bodies' natural defences, scientists heard September 8, 2008 at the Society for General Microbiology's Autumn meeting being held at Trinity College, Dublin.
The toxins are manufactured by communities of the hospital superbug Pseudomonas aeruginosa called biofilms, which are up to a thousand times more resistant to antibiotics than free-floating single bacterial cells.
"This is the first time that anyone has successfully proved that the way the bacteria grow - either as a biofilm, or living as individuals - affects the type of proteins they can secrete, and therefore how dangerous they can potentially be to our health," says Dr Martin Welch from the University of Cambridge, UK.
"Acute diseases caused by bacteria can advance at an astonishing rate and tests have associated these types of disease with free-floating bacteria. Such free-floating bugs often secrete tissue-damaging poisons and enzymes to break down our cells, contributing to the way the disease develops, so it is natural to blame them. By contrast, chronic or long-term infections seem to be associated with biofilms, which were thought to be much less aggressive," says Dr Welch.
The toxins are manufactured by communities of the hospital superbug Pseudomonas aeruginosa called biofilms, which are up to a thousand times more resistant to antibiotics than free-floating single bacterial cells.
"This is the first time that anyone has successfully proved that the way the bacteria grow - either as a biofilm, or living as individuals - affects the type of proteins they can secrete, and therefore how dangerous they can potentially be to our health," says Dr Martin Welch from the University of Cambridge, UK.
"Acute diseases caused by bacteria can advance at an astonishing rate and tests have associated these types of disease with free-floating bacteria. Such free-floating bugs often secrete tissue-damaging poisons and enzymes to break down our cells, contributing to the way the disease develops, so it is natural to blame them. By contrast, chronic or long-term infections seem to be associated with biofilms, which were thought to be much less aggressive," says Dr Welch.
