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The genetics of side-effects

hospital
© Banc d'Imatges Infermeres/CC BY-NC-ND 2.0
Some 95% of people have a gene variant that affects their response to at least one drug.
Henk-Jan Guchelaar knows all too well the serious problems that the side-effects of medication can cause. As a professor of clinical pharmacy at the University of Leiden in the Netherlands, he has spent the last two decades trying to get the link between medicine and our genes recognised more widely.

The stories he hears from patients and their families bring home the impact that these gene-drug interactions can have. It can even have fatal consequences, as one man described to him.

'He told me about his wife, who had breast cancer and underwent surgery. The prognosis was very good. The tumour was removed by the surgeon but, to prevent micro-metastases, his wife had to receive six courses of (chemotherapy drug) fluorouracil. During the second infusion of the drug, the patient collapsed, went to the intensive care unit and died,' he said.

Comment: One wonders when they'll apply this same thinking to vaccines...


Cow

Meat is Magnificent: Water, Carbon, Methane & Nutrition

sustainabledish
© sustainabledish
"When we try to pick out anything by itself, we find it hitched to everything else in the Universe." - John Muir

There was a recent article in The Washington Post entitled "Meat is Horrible", once again vilifying meat, that was full of inaccurate statements about the harm cattle impose on the land, how bad it is for our health, and how it should be taxed. Stories like this are all too common and we've absolutely got to change our thinking on what's causing greenhouse gas emissions and our global health crisis.

Comment: Red meat consumption is actually excellent for optimal human health


Syringe

Here's why you should skip the COVID vaccine

Covid vaccine
© Chris Gash/New York Times
"The world has bet the farm on vaccines as the solution to the pandemic, but the trials are not focused on answering the questions many might assume they are."

Peter Doshi, associate editor of the British Medical Journal and assistant professor of pharmaceutical health services research at the University of Maryland School of Pharmacy

"The difference between genius and stupidity is that genius has its limits."
Albert Einstein
The new Covid vaccines will make billions of dollars for the big pharmaceutical companies, but here's what they won't do:
  1. The vaccines will not cure Covid
  2. The vaccines will not prevent people from contracting Covid
  3. The vaccines will not prevent Covid-related hospitalizations
  4. The vaccines will not prevent Covid-caused deaths
Now, I know what you're thinking. You're thinking, "If the vaccine does not protect me from getting Covid (or dying from Covid), then why should I take it?"

Hearts

Activating the vagus nerve could lower your risk for Covid-19 and other inflammatory conditions

social distancing, Domino Park
© Paul Martinka
People social distancing at Domino Park in Williamsburg, Brooklyn.
Like other apes, humans are social animals. We evolved to live in codependent communities, and we do poorly if deprived of interpersonal contact.

Everyone has a different threshold for social interaction. But nearly all of us tend to become distressed when cut off from others, and our immune system responds to this distress by ramping up its defenses. A new study in the journal Neuroscience & Biobehavioral Reviews finds that social isolation is associated with a rise in inflammation-promoting molecules, including some that are implicated in severe Covid-19. And past research has linked loneliness to poor cellular immune health and increased viral loads during an infection.

All of these cellular and immune changes are worrying in the context of SARS-CoV-2. Inflammation is a unifying feature of illness, and out-of-control inflammation seems to be a common feature of severe Covid-19.

Comment: Eiriu Eolas is an excellent breath and meditation program designed to stimulate healthful vagal nerve activity.. Find it free here.


Flashlight

Peer-reviewed hydroxychloroquine study finds 84% fewer hospitalizations among early treated outpatients

hydroxychloroquine
© GEORGE FREY/AFP via Getty Images
'What differentiates this study is that patients were diagnosed very early with COVID-19 in an outpatient setting, and only high-risk patients were treated early on'

A peer-reviewed study analyzing the effectiveness of a triple drug cocktail including hydroxychloroquine in treating COVID-19 patients found that the treatment was effective and that it significantly reduced hospitalization and mortality rates for those in the treatment group.

The study, authored by the controversial Dr. Vladimir Zelenko in partnership with two German doctors, was accepted for peer-review and will be published in the December issue of the International Journal of Antimicrobial Agents. An online-only version of the study was published Oct. 26.

Dr. Zelenko and team, Drs. Roland Derwand and Martin Scholz, sought to describe the outcomes of high-risk patients with laboratory-confirmed cases of COVID-19 who received early treatment with zinc, low-dose hydroxychloroquine, and azithromycin. A total of 141 diagnosed COVID-19 patients were prescribed the triple treatment over a five-day period. They were compared with a control group of 377 confirmed COVID-19 patients who did not receive the treatment.

Attention

A low-fat, high-carb diet has been the largest public health experiment in history. As the world gets ever fatter, we MUST rethink

overweight americans fat
© Getty Images / Zena Holloway
New research suggests that four billion people globally will be overweight in 2050. This trend can be traced back to the 'low-fat, high-carb' guidelines first issued in the 70s, and should prompt a major U-turn on dietary advice.

A recent report from the Potsdam Institute predicts that by 2050 there will be four billion overweight people in the world, with one-and-a-half billion of them obese. This is not entirely surprising. The world has been getting fatter for years, and things do not seem to be slowing down.

This Organisation for Economic Cooperation and Development (OECD) graph, which looks at the rise in overweight adults in a number of different countries, shows that the trend seems inexorably upward.

Comment:


Life Preserver

American with rare muscle atrophy walks again thanks to treatment in Russia - US doctors gave him no chance of recovery

Spencer
An American man with a rare muscle disorder took a chance on Russia after doctors back home gave him little hope of walking again. In the US, Alan Spencer's prognosis varied between being bedridden for life or wheelchair-bound.

Now, after a month of treatment, under the guidance of Russian specialists, he's able to walk on his own.

Spencer first felt something was wrong with his health around five years ago. Initially, it was his hands that lost their strength, then his condition began gradually worsening.

Comment: Russia is at the forefront of numerous scientific endeavours:


Health

Masks are neither effective nor safe: A summary of the science

Woman wearing mask
© Adobe Stock
Print this article and hand it to frightened mask wearers who have believed the alarmist media, politicians and Technocrats in white coats. Masks are proven ineffective against coronavirus and potentially harmful to healthy people and those with pre-existing conditions.

My wife and I dined out last night in a very empty restaurant and the young waitress was required to wear a cloth mask. I asked her how she was doing with the mask and if there were any side effects. She related that was consistently short of breath (when away from the table, she lowered the mask below her nose) and that she had actually passed out because of it a few days earlier, taking her straight to the floor. Fortunately, she was not hurt. - TN Editor
At this writing, there is a recent surge in widespread use by the public of facemasks when in public places, including for extended periods of time, in the United States as well as in other countries. The public has been instructed by media and their governments that one's use of masks, even if not sick, may prevent others from being infected with SARS-CoV-2, the infectious agent of COVID-19.


Comment: See also:


Cow

Meat-free diets linked with greater risk of breaking bones - Oxford University study

vegetarian
© coldsnowstorm/Getty Images
A vegetarian diet may increase the risk of breaking bones
People who don't eat meat are more at risk of breaking bones, especially their hips, according to the largest study yet of this risk. The effect may stem from a lack of calcium and protein in their diet, as well as the fact that they tend to be thinner and so have less flesh to cushion a fall.

Several previous studies have shown that vegetarians have weaker bones than meat eaters, but it was unclear if this had any meaningful effect on their risk of fractures.

The new research took advantage of a long-running study called EPIC-Oxford, originally set up to look at whether diet influences the risk of cancer by following the health of about 65,000 people in the UK from 1993 onwards. The study recorded people's typical diet and tracked their health through hospital records.

Comment: There's a lot more to bone strength than just calcium consumption, but it's clear that a diet rich in healthy meat and animal fat is the best foundation: And check out SOTT radio's:


Life Preserver

4-year-old almost dies due to lung infection caused by prolonged mask wearing - doctor rants 'how many children must die?'

Children wearing masks
© healthimpactnews.com
How long are parents going to continue masking their children causing great harm to them, even to the point of risking their lives?

Dr. Eric Nepute in St. Louis took time to record a video rant that he wants everyone to share, after the 4-year-old child of one of his patients almost died from a bacterial lung infection caused by prolonged mask use.

He states:
The system is set up to kill people right now.