Health & Wellness
The intervention that shows the most benefit? Keeping active. Millions of dollars of research to tell us that "motion is lotion, baby." Not as in moving propane tanks or other heavy activity that makes the pain worse, but just keeping moving.
The rest of the story reads like a miracle.
What they have learned thus far is that illness and sleep disruption may be a two-way street: sick flies can't sleep, and losing sleep makes them more susceptible to infection.
"When flies get sick, they stop sleeping," said David Schneider, PhD, assistant professor of microbiology and immunology. "Disrupting sleep in turn disrupts the immune system, which makes them even more infected and it's downhill from there in a 'spiral of death.'" Schneider is the senior author of a study on the sleep patterns of flies that will be published in the May 15 issue of Current Biology.
Schneider worked with postdoctoral scholar Mimi Shirasu-Hiza, PhD, who is the study's first author, to examine the connection between illness and sleep patterns by infecting fruit flies with one of two bacteria - Streptococcus pneumoniae or Listeria monocytogenes.
The infected flies lost their "day" and "night" patterns of activity, which are part of the regular changes that occur in the course of a day, called circadian rhythm. Uninfected flies alternate between 12 hours of high activity and 12 hours of low activity. The researchers found the sick flies had fewer sleep sessions and shorter periods of continuous sleep than did healthy flies. They basically just didn't sleep well, concluded the researchers.
These "fictive learning" experiences, governed by what might have happened under different circumstances, "often dominate the evaluation of the choices we make now and will make in the future, " said Dr. P. Read Montague, Jr., professor of neuroscience at BCM and director of the BCM Human Neuroimaging Laboratory and the newly formed Computational Psychiatry Unit. "These fictive signals are essential in a person's ability to assess the quality of his or her actions above and beyond simple experiences that have occurred in the immediately proximal time."
Using techniques honed in previous experiments that studied trust, Montague and his colleagues used an investment game to test the effects of these "what if" thoughts on decisions in 54 subjects. Using functional magnetic resonance imaging (fMRI) to measure blood flow changes in specific areas of the brain, they precisely measured responses to economic instincts.
These blood flow changes in the brain reflect alterations in the activity of nerve cells in the vicinity. In this case, they measured the brain's response to "what could have been acquired" and "what was acquired." This newly discovered "fictive learning" signal was measured, localized and precisely parsed from the brain's standard reward signal that reflects actual experience.
The research, which was conducted under the direction of Dr. Mark Leikin and Prof. David Share, evaluated 129 first graders that were divided into three groups: bilingual Hebrew and Russian speakers who had acquired literacy skills in Russian before being exposed to Hebrew reading skills; bilingual children who spoke but had not learned how to read Russian; and monolingual Hebrew speakers. The research involved administering tests which evaluated the children's language skills at the beginning of first grade and tests that evaluated their reading and writing skills at the end of first grade.
The results revealed that children who acquired Russian reading skills before learning to read Hebrew showed a distinct advantage over the other groups in their ability to distinguish between sounds and greater fluency and accuracy in reading. The research did not find any differences in the reading skills of monolingual Hebrew speakers and bilingual Hebrew and Russian speakers who did not read Russian. According to Dr. Schwartz, this result supports the existing theories that bilingualism alone does not enhance development of reading skills but that reading skill acquisition is easier when a child already knows how to read another language.
Juan Maeso, 65, a former chief anaesthetist at the La Fe de Valence maternity unit in eastern Spain, will in effect serve a maximum 20 years in prison, as per Spanish law.
The former doctor, who was a drug addict and a Hepatitis C carrier, was found guilty of infecting 275 people in four hospitals in the Valencia region between 1988 and 1997, after a trial which opened in September 2005.
No need to spend hours in the gym in pursuit of a perfect body; no fake tans, sunbeds or hours baking on the beach to get a tan; and you could say goodbye to facials and expensive anti-ageing treatments.
Just swallow a tablet with breakfast and you're done.