Health & Wellness
Samples of lung tissue taken from soldiers who died in the pandemic, the worst of the 20th century, showed evidence of damage both by the flu virus and by pneumonia-causing bacteria.
Such so-called co-infections also cause many influenza-related deaths today.
"In essence, the virus landed the first blow while bacteria delivered the knockout punch," Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, which conducted the study, said in a statement.
A paper on the methylene blue study, conducted by Hani Atamna, PhD, and a his team at Children's, was published in the March 2008 issue of the Federation of American Societies for Experimental Biology (FASEB) Journal. Dr. Atamna's research found that methylene blue can prevent or slow the decline of mitochondrial function, specifically an important enzyme called complex IV. Because mitochondria are the principal suppliers of energy to all animal and human cells, their healthy function is critical.
"The results are very encouraging," said Dr. Atamna. "We'd eventually like to try to prevent the physical and cognitive decline associated with aging, with a focus on people with Alzheimer's disease. One of the key aspects of Alzheimer's disease is mitochondrial dysfunction, specifically complex IV dysfunction, which methylene blue improves. Our findings indicate that methylene blue, by enhancing mitochondrial function, expands the mitochondrial reserve of the brain. Adequate mitochondrial reserve is essential for preventing age-related disorders such as Alzheimer's disease."
The baby boy was one of two children transferred to Alberta Children's Hospital in Calgary from Lethbridge Regional Hospital late last week with what was originally speculated to be flesh-eating disease.
The findings will be reported during a 2 p.m. (EDT) poster session, "Improving Our Practice -- Focus on Ethnic Psychology," on Sunday, Aug. 17, at the annual meeting of the American Psychological Association in Boston.






