Imagine being treated like a suspected criminal or terrorist by immigration officials all because you have cancer and your doctor gave you a drug that causes a strange side effect -- your fingerprints have disappeared into thin air. Does that sound like a novel or movie plot? Unfortunately for one 62-year-old cancer patient, and possibly others, this was anything but fiction.
In a letter just published in the cancer journal Annals of Oncology, Dr Eng-Huat Tan, a cancer specialist in the medical oncology department at the National Cancer Centre in Singapore, reported on a perplexing case of missing fingerprints due to the cancer drug capecitabine. And he has warned that other people taking the drug should start carrying a doctor's letter with them if they want to travel to the U.S.
Here's what happened: Dr. Tan's 62-year-old patient (known only as Mr. S., due to privacy considerations) was suffering from metastatic nasopharyngeal carcinoma -- a head and neck cancer that had spread. Fortunately, the malignancy had responded well to treatment and, in hopes of preventing a recurrence of the malignancy, the patient was put on capecitabine, the generic name for the drug sold in the U.S. as Xeloda. According to the U.S. Food and Drug Administration (FDA), in some people, capecitabine stops cancer cells from growing and decreases the size of tumors. But it also can produce a host of adverse side-effects including severe diarrhea, life-threatening bleeding and hand-foot syndrome. The latter problem is a condition that stems from chronic inflammation of the palms and/or soles of the feet. It makes the skin peel, bleed and develop ulcers or blisters. "This can give rise to eradication of finger prints with time," Dr. Tan stated in his letter.
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