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Women twice as likely as men to have asthma

woman asthma
© Phanie Sarl/Corbis
Women are twice as likely as men to have asthma, and this gender difference may be caused by the effects of sex hormones on lung cells, a study has found.

Researchers found that testosterone hindered an immune cell linked to asthma symptoms, such as inflammation and mucus production in the lungs.

"When we started this study, we really thought that ovarian hormones would increase inflammation, more so than testosterone making it better," said Dawn Newcomb, from the Vanderbilt University in the US.

"I was surprised to see that testosterone was more important in reducing inflammation," said Newcomb, senior author of the study published in the journal Cell Reports.

Prior studies have found that, before puberty, boys have about 1.5 times higher rate of asthma than girls. That trend reverses after puberty, when women are twice likely to have asthma as men, researchers said.


This pattern continues until women hit menopause, and then the asthma rates in women start to decline.

Health

Disrupting circadian rhythm of muscle cells could lead to diabetes

chronobiology
Maintaining a stable and steady circadian rhythm can be a challenge for many people. Millions of people participate in shift work or work hours that aren't conducive to getting enough sleep at night. In addition, the demands of modern life can make it difficult to eat at regular hours. The result is that 60 million people in the United States alone have trouble sleeping. This sleep disruption has been linked to a variety of chronic diseases, including Type 2 diabetes. A new study on the circadian rhythm of muscle cells suggests they may be an important part of this connection.

The Circadian Rhythm of Muscle Cells

When most people think of circadian timekeepers, they think of the brain. The brain is indeed important in synchronizing our internal clocks as well as perceiving and adapting to external cues. However, every organ system has its own rhythm and its own set of cues for moving clocks forward or backward. Muscle cells are no exception.

Comment: See also:


Ambulance

Fighting the cognitive health crisis

dementia, alzheimer's
If you look at the latest stats, you might assume there's no cognitive health crisis. The overall number of dementia cases are going up, but that's because the aging population is growing. Older folks are living longer than ever before, so there are more people around who can develop dementia. Dementia and Alzheimer's rates are dropping in the Western world. Politicians, those archetypical paragons of cognitive aptitude, are hanging around in office longer than ever. Technology, science, and other fields that require large amounts of cognitive ability are progressing.

But broad trends and large numbers are just statistics. However reassuring they are to public policy analysts, they mean nothing to the individual suffering from cognitive decline. They're too abstract. Your grandpa no longer knowing who you are? That's real. You, personally, don't want to lose your cognitive abilities as you age. You, personally, don't want to see the people you love get Alzheimer's. Individual cases matter to those individuals and their loved ones. And it's still happening more than it should.

Comment: Priceless results considering that the protocol was fairly simple. For supporting evidence on each step of this protocol, read:


Syringe

High aluminum found in Autism brain tissue that was "pathologically significant"

Aluminum
New Study Indicates that Widespread Exposure to Aluminum Is Setting the Stage for Catastrophic Neurological Damage

Robert F. Kennedy Note: Dr. Christopher Exley's study is on aluminum in the brains of 10 donors who had autism. They contained some of the highest levels of aluminum ever recorded in human brain, and the aluminum was found in the brain's immune cells, the microglia and the cells which provide support and protection for the neurons, the glia. How does a 15 year old have as much aluminum in his brain as someone who is many decades older who has died of familial Alzheimer's disease? Dr. Exley's findings have shocking implications for today's generation of children who receive 5,000 mcg. of aluminum in vaccines by the age of 18 months and up to 5,250 additional mcg. if all recommended boosters, HPV and meningitis vaccines are administered.

By World Mercury Project Team

Scientists have been aware of aluminum's neurotoxicity for decades. Although aluminum's apologists have tried to shroud the metal's risks in manufactured controversy, a growing number of reports by researchers in the United Kingdom, France, Canada, Israel, the U.S. and elsewhere has furnished substantive evidence linking aluminum to neuropathology, including the epidemics of Alzheimer's disease (AD) and autism spectrum disorder (ASD).

Comment: Astrocytes

Research suggests a new role for astrocytes: maintaining the circadian rhythm

Microglial

How Does Microglia Examine Damaged Synapses?

Vaccine


Heart - Black

VA study finds Vietnam vets may be dying from slow-killing parasite contracted while fighting in SE Asian jungles

vietnam veterans
© AP / Margie Mason
n this Oct. 12, 2017 photo, Mike Baughman, center, plays the bass with Sam Gibson, left, on guitar while Ryan Baughman, right, looks on at a cabin in Herald, W.Va.
A half century after serving in Vietnam, hundreds of veterans have a new reason to believe they may be dying from a silent bullet - test results show some men may have been infected by a slow-killing parasite while fighting in the jungles of Southeast Asia.

The Department of Veterans Affairs this spring commissioned a small pilot study to look into the link between liver flukes ingested through raw or undercooked fish and a rare bile duct cancer. It can take decades for symptoms to appear. By then, patients are often in tremendous pain, with just a few months to live.

Of the 50 blood samples submitted, more than 20 percent came back positive or bordering positive for liver fluke antibodies, said Sung-Tae Hong, the tropical medicine specialist who carried out the tests at Seoul National University in South Korea.

Comment: Parasitic microorganisms: Chances are, you've got them

Iodine to the rescue: This life-saving nutrient has excellent antibacterial, anticancer, antiparasitic, antifungal, and antiviral properties:


Coffee

Moderate coffee consumption linked with lower risks of depression, Parkinson's and dementia

flying coffee
Moderate coffee consumption is linked to reduced depression risk and lower levels of Parkinson's and dementia, new research finds.

Not only that, but the review of more than 200 studies found that drinking 3 to 4 cups of coffee a day is linked to many other benefits.

These include lower levels of heart disease, reduced risk of some cancers, diabetes and liver disease.

The study's authors write:
"Coffee consumption was consistently associated with a lower risk of Parkinson's disease, even after adjustment for smoking, and across all categories of exposure.

Decaffeinated coffee was associated with a lower risk of Parkinson's disease, which did not reach significance.

Consumption had a consistent association with lower risk of depression and cognitive disorders, especially for Alzheimer's disease."

Syringe

Harvard Immunologist: Unvaccinated children pose ZERO risk to anyone and here's why

Tetyana Obukhanych

Tetyana Obukhanych
Dear Legislator:

My name is Tetyana Obukhanych. I hold a PhD in Immunology. I am writing this letter in the hope that it will correct several common misperceptions about vaccines in order to help you formulate a fair and balanced understanding that is supported by accepted vaccine theory and new scientific findings.

Do unvaccinated children pose a higher threat to the public than the vaccinated?

It is often stated that those who choose not to vaccinate their children for reasons of conscience endanger the rest of the public, and this is the rationale behind most of the legislation to end vaccine exemptions currently being considered by federal and state legislators country-wide.

You should be aware that the nature of protection afforded by many modern vaccines - and that includes most of the vaccines recommended by the CDC for children - is not consistent with such a statement.

I have outlined below the recommended vaccines that cannot prevent transmission of disease either because they are not designed to prevent the transmission of infection (rather, they are intended to prevent disease symptoms), or because they are for non-communicable diseases.

People who have not received the vaccines mentioned below pose no higher threat to the general public than those who have, implying that discrimination against non-immunized children in a public school setting may not be warranted.

Comment: See also:


Smoking

Why the ban on smoking in UK's mental health units is cruel

smoking man
© Getty
Smoking is now banned in every NHS mental health unit in England, under the terms of the Health Act in 2007.

Now some hospitals in England and Wales, and all hospitals in Scotland, are bringing in a blanket ban so there is no smoking in the grounds at all.

I feel this is cruel and unusual.

For a start, when you stay in a mental health unit - for anywhere from a few days to a number of months - it becomes your home for that period of time. Most people are free to smoke in their own homes, so surely it's unfair that mental health patients - when at their lowest ebb - are prevented from smoking?

The Minister for Mental Health in Scotland, Maureen Watt said at the time: 'Hospitals are places people go to recover from illness, and they shouldn't have to walk through clouds of smoke.'

Comment: Here are some clues as to why so many schizophrenia patients smoke:


Health

Scarlet fever is making a comeback in the UK

scarlet fever
Scarlet fever, a common cause of childhood death in the 1800s and early 1900s, has seen an upsurge in England since 2011 after decades of decline, scientists said Tuesday.

Identifying the cause for the increased cases was "a public health priority", they warned.

"England is experiencing an unprecedented rise in scarlet fever with the highest incidence for nearly 50 years," said a study published in The Lancet Infectious Diseases, a leading medical journal.

In 2014, that amounted to a scarlet fever notification "for one in 500 children under the age of 10 years." There were no deaths.

"Whilst current rates are nowhere near those seen in the early 1900s, the magnitude of the recent upsurge is greater than any documented in the last century," said study leader Theresa Lamagni of Public Health England, Britain's executive health agency.

Scarlet fever is an infection, usually not serious, with symptoms including a sore throat, headache, high temperature and an itchy, sandpaper-like rash for which the disease is named.

Comment: Victorian diseases like scurvy and scarlet fever increase in the UK


Health

Study finds obesity and diabetes were responsible for almost 800,000 cases of cancer in one year

waistline
© Global Look Press
Obesity and diabetes were to blame for hundreds of thousands of cancer cases worldwide in 2012, according to the results published in a new study.

The combined effect of diabetes and high body mass index (BMI) above the indicator of 25 caused some 792,600 cancers globally five years ago, showed the study, led by Dr Jonathan Pearson-Stuttard from the Imperial College London's Faculty of Medicine.

"While obesity has been associated with cancer for some time, the link between diabetes and cancer has only been established quite recently," Pearson-Stuttard said, as quoted by AFP.

"Our study shows that diabetes - either on its own or combined with being overweight - is responsible for hundreds of thousands of cancer cases each year across the world," he added. Although, if taken separately, being overweight led to twice as many cancer cases as diabetes, the study showed.