Health & Wellness
Researchers say the animal study is encouraging and will lead to further clinical studies in humans.
"Metabolic syndrome is a cluster of traits that can greatly increase your risk of heart disease, stroke and Type 2 diabetes, so it's a serious condition that significantly affects public health," said study co-author Dr. Steven F. Bolling, a cardiac surgeon at the University of Michigan Cardiovascular Center who also heads the U-M Cardioprotection Research Laboratory, where the study was performed. "Lifestyle changes have been shown to lower the odds of developing metabolic syndrome, and there is tremendous interest in studying the impact of particular foods that are rich in antioxidants, such as cherries."
Metabolic syndrome (also called insulin resistance syndrome) has become increasingly common in the United States, especially among adults in their mid-30s.
Researchers said that in the year before their Parkinson's disease was diagnosed, people who were taking anti-depressants were nearly twice as likely to develop Parkinson's disease as those who were not taking anti-depressants, the Harvard School of Public Health said in a release.
The research, which was conducted on rats, suggests that the human brain may be more adept at distinguishing smells than previously thought. The work comes from studies in the laboratory of Leslie Kay, Assistant Professor in Psychology at the University, who is looking at the ways animals perceive sensory stimuli by focusing on the neural basis of olfactory perception and how context and experience influence it.
The research demonstrates the importance of smell as a means for people to gather information from their environment. Smell is often an undervalued sense because people are more aware of the visual aspects of their perceptions, the researchers said.
Those visual distractions lead people to ignore their ability to detect smells, something the brain is apparently well equipped to do, according to Kay and Jennifer Beshel, a graduate student at the University, who presented results of her dissertation research in the talk, "Olfactory bulb gamma oscillations are dynamically altered to adjust to task demands," at the annual meeting of the Association for Chemoreception Sciences in Sarasota, Florida.
The results, reported in the March issue of the journal Youth & Society, come as attention is focused on the mass shooting at Virginia Tech, an extreme example of student aggression at its most lethal.
Though it's no magic solution , the research could help ensure and direct intervention in middle schools where students need it most, the scientists say.
It could also hold clues for pharmacologists working to develop drugs to help people adjust to shift work or jet lag. There are further implications for the study of causes of some psychiatric disorders.
The altered gene, named "after hours" or Afh, is a variant of a gene called Fbxl3, which had not been linked to the body clock that keeps our metabolism, digestion and sleep patterns in tune with the rising and setting of the sun.
The discovery involved scientists from the Medical Research Council Mammalian Genetics Unit, Oxfordshire, the MRC Laboratory for Molecular Biology, Cambridge, and colleagues based at New York University.