If you are a man, you've probably had the fear of prostate cancer drilled into you -- along with the idea that it is critical to your health, and probably your life, to have regular prostate cancer screenings. But two just released large randomized trials indicate that if there is any benefit to screening, it is extraordinarily small. The authors of a review of this research, just published in CA: A Cancer Journal for Clinicians, Otis W. Brawley, M.D. of the American Cancer Society and Donna Ankerst, Ph.D. and Ian M. Thompson, M.D. of the University of Texas Health Science Center at San Antonio, say that prostate cancer is almost inevitable in men as they grow older, so a medical goal to find more prostate cancers is not acceptable.
In fact, they point out that principles of good public health policy call for screenings only if they reduce the risk of death and/or suffering from prostate cancer, or reduce health care costs when compared with a non-screening scenario. And according to the new research, prostate cancer screenings do none of these things. But they can cause havoc in a man's life.
Health & Wellness
According to the study, thimerosal-induced cellular damage caused concentration- and time-dependent mitochondrial damage, reduced oxidative-reduction activity, cellular degeneration, and cell death. Thimerosal at low concentrations induced significant cellular toxicity in human neuronal and fetal cells.
Thimerosal was found to be significantly more toxic than the other metal compounds examined.
A woman lost 55 pounds after undergoing hypnosis to implant memories of a gastric band surgery in her head.
"I've tried every other diet and exercise plan the world has to offer," said the woman, Marion Corns. "Now I am able to shed up to three pounds a week because I believe I've had a band fitted into my stomach. Bizarrely, I can remember every part of the 'procedure' - including being wheeled into theatre, the clink of the surgeon's knife and even the smell of the anesthetic."
"I've tried every other diet and exercise plan the world has to offer," said the woman, Marion Corns. "Now I am able to shed up to three pounds a week because I believe I've had a band fitted into my stomach. Bizarrely, I can remember every part of the 'procedure' - including being wheeled into theatre, the clink of the surgeon's knife and even the smell of the anesthetic."
People who understand body cleansing, understand what detoxification symptoms are. Medical professionals understand the symptoms that make up what we call disease. But the odd thing is that most detoxification symptoms are also the symptoms used to detect a disease.
If you think about that for a minute, what does it really tell you? The truth is: When we have a problem in the body, the body tries to detoxify itself to remove the problem. That is why we experience detoxification symptoms in the presence of a problem. Yet, your doctor will often call the presence of these symptoms the problem, without understanding what the body is trying to do about the problem.
If you think about that for a minute, what does it really tell you? The truth is: When we have a problem in the body, the body tries to detoxify itself to remove the problem. That is why we experience detoxification symptoms in the presence of a problem. Yet, your doctor will often call the presence of these symptoms the problem, without understanding what the body is trying to do about the problem.
Elevated cholesterol levels in midlife - even levels considered only borderline elevated - significantly increase the risk of Alzheimer's disease and vascular dementia later in life, according to a new study by researchers at Kaiser Permanente's Division of Research and the University of Kuopio in Finland.
The study appears in the journal Dementia & Geriatric Cognitive Disorders.
The four-decade study of 9,844 men and women found that having high cholesterol in midlife (240 or higher milligrams per deciliter of blood) increases, by 66 percent, the risk for Alzheimer's disease later in life.
The study appears in the journal Dementia & Geriatric Cognitive Disorders.
The four-decade study of 9,844 men and women found that having high cholesterol in midlife (240 or higher milligrams per deciliter of blood) increases, by 66 percent, the risk for Alzheimer's disease later in life.
A team of US scientists has for the first time unravelled the entire genetic code of HIV, the virus that causes AIDS, paving the way for a better understanding of how these types of viruses infect humans and hopefully speeding up the discovery and development of new drugs.
The work was done by Dr Kevin Weeks, a chemistry professor of the College of Arts and Sciences at the University of North Carolina (UNC) at Chapel Hill, and colleagues, and features as the cover story of the 6 August issue of Nature.
Before this work, researchers had only modeled small regions of the HIV genome, which is very large and made of two strands of nearly 10,000 building blocks or nucleotides each.
The work was done by Dr Kevin Weeks, a chemistry professor of the College of Arts and Sciences at the University of North Carolina (UNC) at Chapel Hill, and colleagues, and features as the cover story of the 6 August issue of Nature.
Before this work, researchers had only modeled small regions of the HIV genome, which is very large and made of two strands of nearly 10,000 building blocks or nucleotides each.
Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. The REDD1 protein is a critical inhibitor of the mTOR signaling pathway, which controls cell growth and proliferation. The study was published in the August 2009 issue of EMBO Reports.
As part of the cellular stress response, REDD1 is expressed in cells under low oxygen conditions (hypoxia). The Burnham scientists showed that the REDD1 protein rapidly undergoes degradation by the ubiquitin-proteasome system, which allowed for the recovery of mTOR signaling once oxygen levels were restored to normal.
"Cells initially shut down the most energy-costly processes, such as growth, when they're under hypoxic stress. They do this by expressing REDD1, which inhibits the mTOR pathway" said Dr. Chiang. "But when the cell needs the mTOR pathway active, REDD1 has to be eliminated first. Because the REDD1 protein turns over so rapidly, it allows the pathway to respond very dynamically to hypoxia and other environmental conditions."
As part of the cellular stress response, REDD1 is expressed in cells under low oxygen conditions (hypoxia). The Burnham scientists showed that the REDD1 protein rapidly undergoes degradation by the ubiquitin-proteasome system, which allowed for the recovery of mTOR signaling once oxygen levels were restored to normal.
"Cells initially shut down the most energy-costly processes, such as growth, when they're under hypoxic stress. They do this by expressing REDD1, which inhibits the mTOR pathway" said Dr. Chiang. "But when the cell needs the mTOR pathway active, REDD1 has to be eliminated first. Because the REDD1 protein turns over so rapidly, it allows the pathway to respond very dynamically to hypoxia and other environmental conditions."
A common treatment that uses medical cement to fix cracks in the spinal bones of elderly people worked no better than a sham treatment, the first rigorous studies of the popular procedure reveal.
Pain and disability were virtually the same up to six months later, whether patients had a real treatment or a fake one.
Tens of thousands of Americans each year are treated with bone cement, especially older women with osteoporosis, some of them stooped and unable to stand up straight. The treatment is so widely believed to work that the researchers had a hard time getting patients to take part when it was explained that half of them would not get the real thing.
Pain and disability were virtually the same up to six months later, whether patients had a real treatment or a fake one.
Tens of thousands of Americans each year are treated with bone cement, especially older women with osteoporosis, some of them stooped and unable to stand up straight. The treatment is so widely believed to work that the researchers had a hard time getting patients to take part when it was explained that half of them would not get the real thing.
Junk food is killing us slowly with diabetes, heart disease and cancer. But we can't stop because we're hooked, and the food industry is the pusher.
Every chef is said to have a secret junk food craving. For Thomas Keller, chef-owner of Per Se and The French Laundry, two of the most acclaimed restaurants in the country, it's Krispy Kreme Donuts and In-N-Out cheeseburgers. For David Bouley, New York's reigning chef in the '90s, it's "high-quality potato chips."
"Father of American cuisine" James Beard "loved McDonald's fries," while Paul Bocuse, an originator of nouvelle cuisine, once declared McDonald's "are the best French fries I have ever eaten." Masaharu Morimoto is partial to "Philly cheese steaks," and Jean-Georges Vongerichten confesses a weakness for Wendy's spicy chicken sandwich. Other accomplished but less-famous chefs admit to craving everything from Peanut M&Ms, Pringles and Combos to Kettle Chips and Kentucky Fried Chicken.
Every chef is said to have a secret junk food craving. For Thomas Keller, chef-owner of Per Se and The French Laundry, two of the most acclaimed restaurants in the country, it's Krispy Kreme Donuts and In-N-Out cheeseburgers. For David Bouley, New York's reigning chef in the '90s, it's "high-quality potato chips."
"Father of American cuisine" James Beard "loved McDonald's fries," while Paul Bocuse, an originator of nouvelle cuisine, once declared McDonald's "are the best French fries I have ever eaten." Masaharu Morimoto is partial to "Philly cheese steaks," and Jean-Georges Vongerichten confesses a weakness for Wendy's spicy chicken sandwich. Other accomplished but less-famous chefs admit to craving everything from Peanut M&Ms, Pringles and Combos to Kettle Chips and Kentucky Fried Chicken.
