A British-based drugmaker has made a groundbreaking offer to the National Health Service to cover the cost of a £25,000 cancer drug if a patient using it failed to show adequate progress.
The NHS would only pay for the new drug, Velcade, when patients responded well to it, under a joint proposal from Janssen-Cilag the drugs maker, and the National Institute for Clinical Excellence, the body that recommends which treatments the NHS should adopt.
Jan Grzebski, a 65-year-old Polish railwayman who fell into a coma following an accident regained consciousness 19 years later, Polish media reported on Saturday.
In 1988, Grzebski fell into a coma after sustaining head injuries as he was attaching two train carriages. Doctors also found cancer in his brain and said he would not live. Grzebski's wife Gertruda Grzebska took him home.
Daniel DeNoon
WebMDTue, 05 Jun 2007 03:37 UTC
Eighty-five percent of women are pleased with their partner's penis proportions - yet many normal men suffer "small-penis syndrome," urologists report.
Small-penis syndrome is the anxiety of thinking one's penis is too small - even though it isn't. It's a totally different condition from having a truly tiny tinkler, a condition known by the cold, clinical name of micropenis.
Diet Coke was first introduced in the US in July 1982 and today it is the fourth most commonly consumed carbonated beverage in the world.
Apart from being the beverage of choice for sugar-phobic individuals the world over, Coca-Cola is one of the longest standing 'corporate partners' (since 1974) of the Fédération Internationale de Football Association (FIFA). In 1998 the company signed an unprecedented eight-year agreement to sponsor FIFA events - not just the prestigious World Cup, but also the Women's World Cup, the Confederation Cup, various youth championships and the upcoming World Cup Trophy Trip, a roadshow that will take the FIFA World Cup Trophy on tour to cities throughout the world.
Why do so many people continue to suffer from life-altering, chronic pain long after their injuries have actually healed"
The definitive answer -- and an effective treatment -- has long eluded scientists. Traditional analgesic drugs, such as aspirin and morphine derivatives, haven't worked very well.
A Northwestern University researcher has found a key source of chronic pain appears to be an old memory trace that essentially gets stuck in the prefrontal cortex, the site of emotion and learning. The brain seems to remember the injury as if it were fresh and can't forget it.
With new understanding of the pain source, Vania Apkarian, professor of physiology, and of anesthesiology, at Northwestern's Feinberg School of Medicine, has identified a drug that controls persistent nerve pain by targeting the part of the brain that experiences the emotional suffering of pain. The drug is D-Cycloserine, which has been used to treat phobic behavior over the past decade.
In animal studies, D-Cycloserine appeared to significantly diminish the emotional suffering from pain as well as reduce the sensitivity of the formerly injured site. It also controlled nerve pain resulting from chemotherapy, noted Apkarian, who is a member of the Robert H. Lurie Comprehensive Cancer Center at Northwestern University.
Nicole Martin
TelegraphMon, 04 Jun 2007 12:29 UTC
Smokers could be denied routine operations on the NHS unless they quit a month before surgery.
Health managers are considering the move after research showed that smokers take longer to recover from surgery and are more prone to hospital-acquired infections such as MRSA.
Although emergency surgery would not be affected, smokers awaiting routine operations such as hip and knee replacements could be refused treatment until they kick the habit.
The proposals, which have been drawn up by Leicester City West Primary Care Trust, could be extended to other areas.
The Leicester plans would involve smokers being given counselling and nicotine patches to help them stop. But the patients would have to give a blood sample to prove they had quit before being put on the waiting list and admitted for elective non-emergency surgery.
Spanish doctors have converted a man's right hand into his left, transplanting it onto the left arm and changing the place of the thumb, representatives of the medical team said on Monday in the eastern city of Valencia.
The 63-year-old man had lost his left hand in an accident four decades ago.
Three years ago, he suffered a stroke which made him unable to use the right side of his body.
The ability to learn from experience is of central importance to human existence. It allows us to acquire many of the skills we need to complete a wide variety of complicated, multi-step tasks in an efficient manner. It also creates habit - a critical, if often overlooked factor in the product and service choices consumers make. An important new study from the Journal of Consumer Research demonstrates how this "cognitive lock-in" can cause us to remain loyal to a product, even if objectively better alternatives exist.
"We find that consumers typically are not aware that this mechanism is a powerful determinant of the choices they make," write Kyle B. Murray (University of Western Ontario) and Gerald Häubl (University of Alberta).
Murray and Häubl examine a theory of cognitive lock-in centered around the notion of skill-based habits of use, that is, how using or purchasing a product becomes easier with repetition. In a series of experiments, they find that people are more influenced by their perceptions of ease-of-use rather than how objectively easy a product is to use.
How a legal case could cripple one of modern medicine's greatest achievements
On June 11, in an unprecedented action before a federal claims court, lawyers for 4,800 autistic children will argue that vaccines caused autism. If successful, these claims could exhaust the pool of money currently set aside to compensate children who have been hurt by vaccines. Further, lawyers will likely take their claims that vaccines cause autism to civil court, where awards could be enormous. "I don't want to see the drug companies go out of business," said David Kirby, author of the book "Evidence of Harm," speaking on Imus in the Morning in April 2005. But "we are looking at trillions and trillions of dollars of care for these people."
Researchers identify a neural circuit that makes mice perceive ambiguous situations as threatening
People who suffer from anxiety tend to interpret ambiguous situations, situations that could potentially be dangerous but not necessarily so, as threatening. Researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Italy have now uncovered the neural basis for such anxiety behaviour in mice. In the current issue of Nature Neuroscience they report that a receptor for the messenger serotonin and a neural circuit involving a brain region called the hippocampus play crucial roles in mediating fear responses in ambiguous situations.
A mouse that has learned that a certain cue, for example a tone, is always followed by an electrical shock comes to associate the two and freezes with fear whenever it hears the tone even if the shock is not delivered. But in real life the situation is not always so clear; a stimulus will only sometimes be followed by a threat while other times nothing might happen. Normal mice show less fear towards such ambiguous cues than to clearly threatening stimuli.
