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Thu, 21 Oct 2021
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Breast Cancer Breakthrough: Broccoli Component Zaps Cells That Fuel Tumor Growth

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© Getty Images
University of Michigan (U-M) Comprehensive Cancer Center scientists say they've found a compound that could help prevent and potentially treat breast cancer. It's not a drug or a new radiation treatment but a natural component of broccoli and broccoli sprouts. And it has the remarkable ability to target cancer stem cells -- the specific cells responsible for fueling the growth of cancerous breast tumors.

The researchers tested the broccoli compound, known as sulforaphane, in animal studies as well as in breast cancer cell cultures in the lab. Their findings, which were recently published in the journal Clinical Cancer Research, showed sulforaphane not only targeted and killed cancer stem cells, but it also prevented any new malignancies from growing.

What makes this such an extraordinary breakthrough? Current chemotherapies don't do anything to stop cancer stem cells. That's why cancer can recur and spread after chemotherapy. So many researchers have long believed that to control cancer, you have to find a way to eliminate cancer stem cells -- and now it appears sulforaphane does exactly that.

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Placebo Works as Well as Antidepressant Drugs

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© iStockphoto
In many cases of depression, antidepressant drugs provide little or no benefit over the effect of a placebo, according to a study published in the Journal of the American Medical Association.

In a meta-analysis of six prior studies on both the older tricyclic and the newer selective serotonin reuptake inhibitor (SSRI) antidepressants, the researchers found that the less severe the depression, the less effective the drug. The sample included 434 patients who were taking antidepressants and 284 who were getting a placebo.

"The magnitude of benefit of antidepressant medication compared with placebo increases with severity of depression symptoms and may be minimal or nonexistent, on average, in patients with mild or moderate symptoms," the researchers wrote.

Brick Wall

Lawsuit Seeks to Ban Genetically Modified Sugar Beets

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© iStockphoto
A group of Oregon farmers are seeking an injunction against this year's planting of Monsanto's genetically engineered sugar beets. The groups of organic farmers, food safety advocates and conservationists, is seeking to persuade a judge to ban the crop until the USDA provides a proper environmental impact statement proving that the crops are safe and that they will not cross-contaminate nearby fields.

The debate over whether or not to allow GE crops into the food supply has been a hotly debated one, but the biotech industry has been the side unable to prove that its products are safe. Those concerned about the negative consequences of GE crops have plenty of unresolved questions that demand answers prior to any GE crop being approved. Yet in reality, the USDA has succumbed to industry pressure instead, jeopardizing the entire food industry.

Nearly half of the nation's sugar beets are genetically modified. They can be found planted on more than one million acres across ten states. The beets have been engineered to be resistant to Monsanto's "RoundUp" herbicide, but their components are not limited to the fields in which they are planted, spreading across the landscape via pollen and seeds carried in the wind. Because it is impossible to track where GE plant fragments end up, there is no ensuring that any crop is truly non-GE or organic.

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BPA Plastics Chemical Damages Intestines, Study Shows

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© Getty Images
The widespread toxin bisphenol-A (BPA) damages the intestines and may lead to a painful condition known as leaky gut syndrome, according to a study conducted by researchers from the National Institute of Agronomic Research researchers in Toulouse, France, and published in the Proceedings of the National Academy Sciences.

The study "shows the very high sensitivity on the intestine of BPA," the National Institute of Agronomic Research said.

BPA is used to make hard clear plastics for products such as water and baby bottles. It is also used to make dental sealants and composites, and is in the liners food cans, beverages and infant formula. More than 130 studies have linked the hormone-mimicking chemical to a wide variety of health problems, including cancers, birth and reproductive defects, obesity, early puberty onset, behavior disorders and brain damage.

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Toxic Nail Salons: Why Your Nail Polish Color Could be the Next Agent Orange

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"Pick a color!" a pretty, 38-year-old woman named Pong orders, as I enter Tower Nails, a typical Bay Area nail salon owned and staffed by Vietnamese immigrants of childbearing age.

Reds, corals, pinks, creams, blacks, blues, even Kelly greens. Selecting a polish can be as stimulating as shopping for baby names, a fun and serotonin-releasing, female preoccupation witnessed as early as the teenage years. Perhaps that explains the huge proliferation of the affordable walk-in salons - the number of nail salons in California has tripled in the last two decades. The overwhelming majority of the workers are Asian immigrants, and of the 300,000 nail salon workers in the state, 80 percent are Vietnamese. And these women, and perhaps even their customers, may be at risk from a toxic cocktail of chemicals.

The biggest concern is the trio of toluene, formaldehyde and dibutyl phthalate (DBP) found in most base and top coats and polishes. This combination of chemicals has been linked to cancer, birth defects and skin rashes, especially with frequent exposure. Women in America need to ask themselves, are they picking their color or their poison?

Sherlock

Health Claims for Food: Good Science, Please

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© Jeff Keen/flickr
If a shopper who is worried about her risk of heart problems notices a box of cereal that says its whole grains reduce cholesterol, she may be that much more inclined to put it and not another brand of cereal into her grocery cart. Like many people, she knows that cholesterol levels are connected to the chances of having a heart attack.

She may not know that she has just made a biomarker-based decision. Blood levels of cholesterol are one measure used as a biomarker - a benchmark that substitutes for clinical outcomes - for risk of heart attack. How much a customer can trust that cereal's health claim, or for that matter the benefits of a cholesterol-lowering drug, depends on how strongly science connects lowering cholesterol levels with a reduced risk for heart disease.

Better Earth

Ancient Tradition of Water Purification Could Save Lives

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© Trees for Life International
Seeds from the Moringa tree purify water.
Thousand-year-old Indian method of using tree seeds to purify water should be used more widely for tackling waterborne diseases

Indian tree seeds that purify water could dramatically reduce disease in the less-industrialised world, say researchers.

The technique of crushing seeds from the Moringa Oleifera tree and adding them to water has been used in its native India for thousands of years.

Now researchers from Canada say it is time to publicize the technique more widely in order to reduce water born diseases across the world.

Attention

U.S. Cancer Institute Issues Stark Warning on Environmental Cancer Risk

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We are underestimating the risk of exposure to everyday chemicals, says US cancer body

A leading US research body has said the range of confirmed or suspected carcinogens to which we are exposed on a daily basis is cause for serious concern, but UK campaign groups refuse to change their views

The link between exposure to everyday chemicals and cancer risk has been 'grossly underestimated' according to the National Cancer Institute in the US.

The Institute, which advises the US President, has previously focused on better-known causes of cancer such as diet and smoking.

However, its latest report, published this month, urges the US Administration to identify and eliminate environmental carcinogens from workplaces, schools and homes. It estimates there are nearly 80,000 'largely unregulated' chemicals on the market.

Info

C-Sections May Raise Celiac Disease Risk in Offspring

Children born by cesarean section may be more likely to develop celiac disease, a chronic digestive disorder, than children born vaginally, new research finds.

Researchers analyzed data on almost 2,000 children seen at gastrointestinal outpatient clinics for celiac disease, Crohn's disease, ulcerative colitis and other gastrointestinal diseases, and compared their rates of C-section vs. vaginal delivery to children who had not been diagnosed with any gastrointestinal conditions.

Compared to children born vaginally, children delivered by C-section were 80 percent more likely to develop celiac disease.

"We did not find any association with the inflammatory bowel diseases, Crohn's disease and ulcerative colitis," said lead study author Dr. Mathias Hornef of Hannover Medical School in Germany. "We did see a moderate but significant association with celiac disease."

People with celiac disease, an autoimmune disorder, have an abnormal immune reaction to gluten, the protein found in wheat, barley and rye. This leads to inflammation and damage to the lining of the small intestine.

Magic Wand

Unplugging From Your Medicine Cabinet: Respecting the Body's Intelligence

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It may be time to go on a special type of vacation: a drug vacation.* A drug vacation is a time in which you reduce the doses or eliminate entirely whatever drug or drugs you are taking. A drug vacation may give you (and your doctor) an opportunity to learn whether you really need to continue taking this drug or not. More important, this vacation will give your body an opportunity to manifest its everyday self-regulating and self-healing propensities without the crutch of a pharmaceutical agent inhibiting or suppressing its important work.

IF you are ready, step away from the medicine cabinet. You may not even recognize it, but you may be addicted to one or more of the drugs there. It may be time that you received an intervention, though this time, you should probably intervene on yourself rather than have anyone do it for or to you.