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Fri, 05 Nov 2021
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Health

Study reveals connection between gut microbiome and inflammatory bowel disease

gut bacteria
Many people associate the word "bacteria" with something dirty and disgusting. Dr. Pere Santamaria disagrees. Called the microbiome, the bacteria in our bodies have all kinds of positive effects on our health, Santamaria says. "The bacteria we have in our gut actually have many beneficial functions. They help in our digestion, prevent infection by pathogens and educate our immune system on what to fight." Now, a new function of a protein in the gut microbiome reveals potential impacts for those who suffer from inflammatory bowel disease (IBD).

Published last week in Cell, a study by Santamaria and Kathy McCoy, PhD, from the University of Calgary's Cumming School of Medicine (CSM) reveals a new mechanism in the gut microbiome that regulates pro- and anti-inflammatory cells. "We found that a protein expressed by gut bacteria called Bacteroides works to prevent IBD by rapidly recruiting white blood cells to kill a cell of the immune system that is responsible for orchestrating IBD," says McCoy. "We think that this mechanism is likely involved in preventing most people from developing IBD."

Comment: See also:


Red Flag

Knee surgeon warns against wearing Ugg boots

Ugg boots
© Getty
We know, it sounds like something made up by a rival, less comfy, boot manufacturer.

But, alas, it is not.

A leading orthopaedic surgeon has warned against wearing Ugg boots in the winter months, saying they lack support for the lower leg if people buy the wrong size.

And constant wear and tear of the boots can cause the heel to get worn away, which can flatten out the arch of the foot which is needed for posture support.

Both of these can lead to a bad posture, knee pain and even back pain.

Ian McDermott, a knee surgeon in London, said: "This is a bit of a 'red flag' and a sign that it's potentially worth investigating the knee with X-rays and an MRI scan to check exactly what is going on inside the joint.

HAL9000

New therapy device heals the body by reprogramming cells

DNA Design
© God & Science Org
Researchers have developed a device that can switch cell function to rescue failing body functions with a single touch. The technology, known as Tissue Nanotransfection (TNT), injects genetic code into skin cells, turning those skin cells into other types of cells required for treating diseased conditions.

Although cellular therapies represent a promising strategy for a number of conditions, current approaches have faced major translational hurdles, including limited cell sources and the need for cumbersome pre-processing steps.

A new device developed at The Ohio State University can start healing organs in a "fraction of a second," researchers say.

The technology has the potential to save the lives of car crash victims and even deployed soldiers injured on site. It's a dime-sized silicone chip that "injects genetic code into skin cells, turning those skin cells into other types of cells required for treating diseased conditions," according to a release.

In the study published in Nature Nanotechnology, first author Daniel Gallego-Perez of Ohio State demonstrated that the technique worked with up to 98 percent efficiently.

Donut

Shhh! Mainstream news finally admits that diet is a factor in getting cancer

fast food
For years it has been a supposed mystery, but it is finally being acknowledged that a primary cause of cancer in the world today is diet. Studies are now showing that obesity plays an enormous role in one's chances of getting cancer, and the main cause of obesity is the type of foods people eat. It is in large part a lifestyle disease, and the most important relevant lifestyle choice is food.
Overall, we estimated that 40.8% of incident cancer cases were attributable to exposure to the 24 factors included in the analysis (Table 2). Tobacco smoking was responsible for the greatest cancer burden, accounting for an estimated 15.7% of all incident cancer cases (2485 cases), followed by physical inactivity and excess body weight, which were responsible for an estimated 7.2% and 4.3% of incident cancer cases, respectively. All other exposures of interest were estimated to be responsible for less than 4.0% of incident cancer cases each. [Source]
More specifically, researchers are pointing out the connection between the body's insulin response to food and cancer metabolism. In short, there is a paradigm shift taking place and we are admitting that food can either feed or starve cancer cells. Here, in a piece for The Los Angeles Times, writer Sam Apple explains this connection:

Comment: See also:


Health

Catechins found in green tea can help your heart and brain

green tea
If you could have a cup of green tea and fight Alzheimer's disease in the process, how many cups would you have? The ancient beverage has been recognized for millennia as having a dramatic and positive impact on human health, but its potential for improving several aspects of your brain, as well as your heart, is becoming more clear thanks to ongoing research.

After all, nearly 50 million people worldwide - one of every nine people over the age of 651 - are wrestling with this devastating disease, described as a neurodegenerative condition evidenced by a progressively advancing mental decline that affects memory and behavior. Experts say that by 2050, that number could surpass 131.5 million.2

While scientists weren't yet clear on what mechanisms made the green tea-for-Alzheimer's link possible, new research, covered in the Journal of the American Chemical Society,3 has determined that antioxidant compounds called catechins are the facilitators (and to a lesser degree, theaflavin polyphenols in black tea).4

Lead study author Giuseppe Melacini, from the chemistry and chemical biology departments at McMaster University in Canada, asserts that the best remedy for Alzheimer's is early intervention. He also notes that using either green tea extracts or their derivatives - as far in advance as 15 to 25 years prior to symptoms appearing - is one method of early intervention.

What he's really suggesting is that anyone wanting to avoid the disease or lessen its effects should begin drinking green tea now rather than waiting until symptoms emerge - although there are a multitude of steps to reduce your Alzheimer's risk beyond drinking green tea.

Life Preserver

Wait a minute—clamping the umbilical cord later could save thousands of preterm babies' lives

Baby
© CC0 Public Domain
Thousands of preterm babies could be saved by waiting 60 seconds before clamping the umbilical cord after birth instead of clamping it immediately - according to two international studies coordinated by the University of Sydney's National Health and Medical Research Council Clinical Trials Centre.

Approved for publishing in the American Journal of Obstetrics and Gynecology, the review led by University of Sydney researchers, assessed morbidity and mortality outcomes from 18 trials comparing delayed versus immediate cord clamping in nearly 3,000 babies born before 37 weeks' gestation. It found clear evidence that delayed clamping reduced hospital mortality by a third and is safe for mothers and pre-term infants.

The review also reported that delayed clamping reduced subsequent blood transfusions and increased neonatal hematocrit, confirming that placental transfusion occurred.

"The review shows for the first time that simply clamping the cord 60 seconds after birth improves survival," said the University of Sydney's Professor William Tarnow-Mordi, senior author.

Health

Silent epidemic of HPV-related cancers spreading among American men

sexualized society

Sexualize the culture, and sooner or later people get hurt.
Jason Mendelsohn had been married for close to 20 years and was happily raising three kids when he noticed the painless lump on his neck while shaving three years ago.

Within days, he had been diagnosed with a deadly form of cancer caused by a virus that he probably caught while in college, decades before.

Mendelsohn, now 48, is the classic victim of head and neck cancer caused by HPV, the human papillomavirus. A new study out this week shows there's a silent epidemic of HPV-related cancers among men.


Comment: As it says in the article itself, vaccines are a waste of time because the population is already infected:
The only way to prevent infection is the HPV vaccine but once someone's already infected - and that's most people over age 26 - the vaccine doesn't help.
At this point, even non-promiscuous people are contracting HPV.


Microscope 1

Westerners headed for extinction? Sperm count levels down in West, but Asian, African and Latin American men 'doing fine'

fall of Rome painting

Is the West headed for a 'Fall of Rome'?
Society sees having children as a major life event.

After all, kids - even the annoying ones - are necessary for the survival of our species.

Yet widespread fertility may become the norm, at least in men.

Sperm counts among men in the west have more than halved in the past 40 years, according to research.

No, this is not some horrific dystopia, but a worsening trend in North America, Europe, Australia and New Zealand.

Interestingly, a new systematic study analysing 42,935 men found no signs of sperm count decline in men from Asia, Africa and South America.

Comment: See also:

Sperm levels in Western men plummeted by more than half in just 4 decades - study

Birth rates hit record low in Italy, population shrinks

A dying country? Russia's birth rate is now higher than the United States'

Number of US states with declining populations of Whites increases to 17


Biohazard

Not soy good? FDA to rescind heart health claim for plant protein

Soy not so good
© Kham / Reuters
The US Food and Drug Administration (FDA) has proposed revoking a claim that soy protein can reduce heart disease, saying that subsequent studies have cast doubt on the 1999 assessment.

"Our review of that evidence had led us to conclude that the relationship between soy protein and heart disease does not meet the rigorous standard for an FDA-authorized health claim," the agency said Monday.

In 1999, the FDA granted a health claim for labeling manufactured food products containing soy, saying that "25 grams of soy protein a day, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease."

In 2012, however, the European Food Safety Authority published a scientific opinion on isolated soy proteins and reduction of cholesterol and concluded that a cause-and-effect relationship was not established.

Comment: See also:
Soy formula is a formula for disaster
How soy affects hormones


Life Preserver

The heavy guns of magnesium: Reducing human suffering in a wide variety of clinical situations

magnesium
There is no healing system more powerful than that which employs Nature's primordial substances; materials so pure and close to nature that they yield benefits without the typical side effects of most drugs. The secret to safe and effective medicine is found in using medicinal substances that do not have side effects in reasonable doses. This is the very meaning of safe, something that will not harm or hurt you.

I received a letter from a professional colleague named George Eby in 2007 that stated that his daughter was destroyed by the terrible side effects of a special type of antibiotic called fluoroquinolones. He said,
"My daughter was stricken with this horrible affliction. Cipro sensitivity causes long term (multiple years to life) chronic pain, weakness and tendon weakness leading to tendon breakage and many other horrible effects, some physical and some mental. This is something that everyone needs to know about. We have been destroyed by cipro. I don't think there is much anyone can do, except to give her magnesium, which is somewhat of an antidote. I am very worried but I haven't lost hope, but I am being realistic. Some of the tendon damage is necrotic and permanent. However, we have studies with rattlesnake venom that produce necrosis on animals and simply applying magnesium (chloride) and zinc (gluconate) topically, the necrosis vanishes." Ten days later I received this email from George.

"Topical magnesium chloride for 10 days = well daughter!"
There is a power and a force in magnesium chloride that cannot be equaled anywhere else in the world of medicine. There is no substitute for magnesium in human physiology; nothing comes even close to it in terms of its effect on overall cell physiology. It goes against a strong gale wind of medical science to ignore magnesium chloride used transdermally in the treatment of any chronic or acute disorder.

Comment: More reasons why magnesium is The Spark of Life: