Cells are equipped with sensors that recognize touch and respond accordingly.
They can even reach out to other cells with nanoscopic tunnels and share parts.
An
article yesterday for
Evolution News about allostery showed how an individual protein or RNA can send information to its distant domains. Information sharing can also occur between chains of molecules arranged in a signaling cascade, where each one triggers action in the next. This is a bit more like the Rube Goldberg technique, except that in cells, it is much more logical and reliable. Here are new examples of
mechanosensing (the ability to sense a touch) and
mechanotransduction (the ability to pass on touch information). A paper on
bioRxiv explains,
"Cells sense the physical properties of their environment, translate them into biochemical signals and adapt their behaviour accordingly."
One such system is the MAPK/ERK pathway that all eukaryotic cells use to get information from the cell surface into the nucleus. A diagram on
Wikipedia's page makes it clear that many individual factors take part. Once the EGFR receptor triggers ERK on the cell's exterior membrane, a signaling cascade begins with at least 16 cofactors and proteins transporting the information to the cell nucleus, which responds by transcribing code proteins or enzymes. ERK signals can also spread throughout the cytoplasm, leading to a variety of responses depending on the nature of the triggering molecule.
Comment: These are only a few of the many stories covering the extreme dangers of CRISPR gene editing that Sott.net has published over the past few years: