
Information sharing across all electrodes before and after vagus nerve stimulation. On the right, the warmer colors (yellow/orange) indicated an increase of connectivity among posterior parietal regions.
The patient, who suffered severe brain damage in a car crash, had shown no signs of awareness or improvement before. He made no apparent purposeful movements and didn't respond to doctors or family at his bedside. But after researchers surgically implanted a device that stimulates the vagus nerve, quiet areas of his brain began to perk up-as did he.
His eyes turned toward people talking and could follow a moving mirror. He turned his head to follow a speaker moving around his bed. He slowly shook his head when asked. When researchers suddenly drew very close to his face, his eyes widened as if he was surprised or scared. When caregivers played his favorite music, he smiled and shed a tear.
The reignited activity bumped his clinical status from vegetative to minimally conscious-an improvement, but still a severely disabled condition. Nevertheless, it gives the researchers optimism that this type of nerve stimulation could help treat other patients with severe brain damage and impaired consciousness. The fact that he was in a vegetative state for so long beforehand makes the results even more convincing, they argue. (The likelihood of regaining consciousness after a single year in an unresponsive state is rather dismal.)















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