A U.S.-British-led international consortium has announced the "1000 Genomes Project" to produce the most detailed map of human genetic variation to date.
The project will involve the sequencing of the genomes of at least 1,000 people from around the world to create the most medically useful human genetics picture ever produced.
Science & Technology
If you've ever wanted to be the Bionic Woman or a Terminator, new research may at least let you see with their eyes. Scientists have taken the first step toward creating digital contact lenses that can zoom in on distant objects and display useful facts.
For the first time, engineers have installed an electronic circuit and lights on a regular contact lens.
For the first time, engineers have installed an electronic circuit and lights on a regular contact lens.
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| ©University of Washington |
| Contact lenses with metal connectors for electronic circuits were safely worn by rabbits in lab tests. |
The deadly Ebola virus, an emerging public health concern in Africa and a potential biological weapon, ranks among the most feared of exotic pathogens.
Due to its virulent nature, and because no vaccines or treatments are available, scientists studying the agent have had to work under the most stringent biocontainment protocols, limiting research to a few highly specialized labs and hampering the ability of scientists to develop countermeasures.
Now, however, a team of researchers from the University of Wisconsin-Madison has figured out a way to genetically disarm the virus, effectively confining it to a set of specialized cells and making the agent safe to study under conditions far less stringent than those currently imposed.
"We wanted to make biologically contained Ebola virus," explains Yoshihiro Kawaoka, a professor of pathobiological sciences in the UW-Madison School of Veterinary Medicine and the senior author of a paper describing the system for containing the virus published today (Jan. 21, 2008) in the Proceedings of the National Academy of Sciences. "This is a great system."
Due to its virulent nature, and because no vaccines or treatments are available, scientists studying the agent have had to work under the most stringent biocontainment protocols, limiting research to a few highly specialized labs and hampering the ability of scientists to develop countermeasures.
Now, however, a team of researchers from the University of Wisconsin-Madison has figured out a way to genetically disarm the virus, effectively confining it to a set of specialized cells and making the agent safe to study under conditions far less stringent than those currently imposed.
"We wanted to make biologically contained Ebola virus," explains Yoshihiro Kawaoka, a professor of pathobiological sciences in the UW-Madison School of Veterinary Medicine and the senior author of a paper describing the system for containing the virus published today (Jan. 21, 2008) in the Proceedings of the National Academy of Sciences. "This is a great system."
Beyond its role as the elixir of all life, water is a very unusual substance: Scientists have long marveled over counter-intuitive properties that set water apart from other solids and liquids commonly found in nature. The simple fact that water expands when it freezes -- an effect known to anyone whose plumbing has burst in winter -- is just the beginning of a long list of special characteristics. (Most liquids contract when they freeze.)
That is why chemical engineer Pablo Debenedetti and collaborators at three other institutions were surprised to find a highly simplified model molecule that behaves in much the same way as water, a discovery that upends long-held beliefs about what makes water so special.
That is why chemical engineer Pablo Debenedetti and collaborators at three other institutions were surprised to find a highly simplified model molecule that behaves in much the same way as water, a discovery that upends long-held beliefs about what makes water so special.
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| ©Unknown |
Cosmic strings are predicted by high energy physics theories, including superstring theory. This is based on the idea that particles are not just little points, but tiny vibrating bits of string Cosmic strings are predicted to have extraordinary amounts of mass - perhaps as much as the mass of the Sun - packed into each metre of a tube whose width is less a billion billionth of the size of an atom.
Lead researcher Dr Mark Hindmarsh, Reader in Physics at the University of Sussex, said: "This is an exciting result for physicists. Cosmic strings are relics of the very early Universe and signposts that would help construct a theory of all forces and particles."
Lead researcher Dr Mark Hindmarsh, Reader in Physics at the University of Sussex, said: "This is an exciting result for physicists. Cosmic strings are relics of the very early Universe and signposts that would help construct a theory of all forces and particles."
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| ©Unknown |
| Dr Hindmarsh said that better data is required before the existence of cosmic strings can be confirmed. |
Like many of us, neutron stars sometimes pack on more pounds than they should. We all know how humans get fat: by eating too much and exercising too little. But nobody knows how a handful of neutron stars end up heavier than the rest. So the apparent discovery of two new examples left astronomers scratching their heads at last week's meeting of the American Astronomical Society in Austin, Texas.
Since its inception in the early 20th century, neuroscience has taught us a tremendous amount about the brain.
Our sensations have been reduced to a set of specific circuits. The mind has been imaged as it thinks about itself, with every thought traced back to its cortical source. The most ineffable of emotions have been translated into the terms of chemistry, so that the feeling of love is just a little too much dopamine. Fear is an excited amygdala. Even our sense of consciousness is explained away with references to some obscure property of the frontal cortex. It turns out that there is nothing inherently mysterious about those 3 pounds of wrinkled flesh inside the skull. There is no ghost in the machine.
Our sensations have been reduced to a set of specific circuits. The mind has been imaged as it thinks about itself, with every thought traced back to its cortical source. The most ineffable of emotions have been translated into the terms of chemistry, so that the feeling of love is just a little too much dopamine. Fear is an excited amygdala. Even our sense of consciousness is explained away with references to some obscure property of the frontal cortex. It turns out that there is nothing inherently mysterious about those 3 pounds of wrinkled flesh inside the skull. There is no ghost in the machine.
New research from the University of Bristol shows that by suppressing one of the genes that normally switches on in wound cells, wounds can heal faster and reduce scarring. This has major implications not just for wound victims but also for people who suffer organ tissue damage through illness or abdominal surgery.
The full recovery of ecological systems, following the most devastating extinction event of all time, took at least 30 million years, according to new research from the University of Bristol.
About 250 million years ago, at the end of the Permian, a major extinction event killed over 90 per cent of life on earth, including insects, plants, marine animals, amphibians, and reptiles. Ecosystems were destroyed worldwide, communities were restructured and organisms were left struggling to recover. This was the nearest life ever came to being completely wiped out.
About 250 million years ago, at the end of the Permian, a major extinction event killed over 90 per cent of life on earth, including insects, plants, marine animals, amphibians, and reptiles. Ecosystems were destroyed worldwide, communities were restructured and organisms were left struggling to recover. This was the nearest life ever came to being completely wiped out.
On the morning of June 12, 1990, Chris McKinstry went looking for a gun. At 11 am, he walked into Nick's Sport Shop on a busy street in downtown Toronto and approached the saleswoman behind the counter. "I'll take a Winchester Defender," he said, referring to a 12-gauge shotgun in the display. She eyeballed the skinny 23-year-old and told him he'd need a certificate to buy it.
Two and a half hours later, McKinstry returned, claiming to have the required document. The clerk showed him the gun, and he handled the pistol grip admiringly. Then, as she returned it to its place, he grabbed another shotgun from the case, yanked a shell out of his pocket, and jammed it into the chamber.
Two and a half hours later, McKinstry returned, claiming to have the required document. The clerk showed him the gun, and he handled the pistol grip admiringly. Then, as she returned it to its place, he grabbed another shotgun from the case, yanked a shell out of his pocket, and jammed it into the chamber.
