The work could ultimately lead to new non-addictive, nicotine-based treatments for some of the 51 million people worldwide who suffer from the disease, the authors of the study envision.
Jerry Stitzel, a researcher at the University of Colorado Boulder Institute for Behavioral Genetics (IBG) and one of four CU Boulder researchers involved in the study, said:
"Our study provides compelling biological evidence that a specific genetic variant contributes to risk for schizophrenia, defines the mechanism responsible for the effect and validates that nicotine improves that deficit."Surprising Nicotine Effect
The study found that when mice with schizophrenic characteristics were given nicotine daily, their sluggish brain activity increased within two days. Within one week it had normalized.















Comment: Why spend all that time and money creating a new drug that works like nicotine? Just use nicotine!