Science & TechnologyS


Bug

New Antibiotics Would Silence Bugs, Not Kill Them

In future, the most effective antibiotics might be those that don't kill any bacteria. Instead the drugs will simply prevent the bacteria from talking with one another.

Drug-resistant bugs are winning the war against standard antibiotics as they evolve resistance to even the most lethal drugs. It happens because a dose of antibiotics strongly selects for resistance by killing the most susceptible bacteria first.

If, however, researchers can identify antibiotics that neutralise dangerous bacteria without killing them, the pressure to evolve resistance can be reduced. One way to do that is to target the constant stream of chatter that passes between bacteria as molecular signals.

Satellite

Fermi, Swift Spy Outburst from Gamma-Ray Star

Fermi Swift Magnetar
© NASAGamma-ray flares from SGR J1550-5418 may arise when the magnetar's surface suddenly cracks, releasing energy stored within its powerful magnetic field.

NASA's Swift satellite and Fermi Gamma-ray Space Telescope have keyed in on a rowdy stellar remnant 30,000 light-years away. The object, already known as a source of pulsing radio and X-ray signals, lies in the southern constellation Norma. It kicked out some moderate eruptions in October, but then it settled down again. Late last month, it roared to life.

"At times, this remarkable object has erupted with more than a hundred flares in as little as 20 minutes," said Loredana Vetere, who is coordinating the Swift observations at Pennsylvania State University. "The most intense flares emitted more total energy than the sun does in 20 years."

The new object has been cataloged as SGR J1550-5418. Because of the recent outbursts, astronomers will classify it as a soft-gamma-ray repeater. Only six such objects are known to science, and they share the trait that they unpredictably send out a series of X-ray and gamma-ray flares. In 2004, a giant flare from another soft-gamma-ray repeater was so intense it measurably affected Earth's upper atmosphere from 50,000 light-years away.

Clock

Super clocks: More accurate than time itself

Image
© Unknown

For those physicists and philosophers puzzled by nature's fourth dimension, Patrick Gill has a wry response. "Time," he says, "is what you measure in seconds."

For Gill, that is a statement of professional pride. He is what you might call Britain's top timekeeper. Within the windowless - and largely clockless - cream-brick confines of the UK's National Physical Laboratory (NPL), near London, Gill and his colleagues are busy developing the next, staggeringly accurate generation of atomic clocks. These tiny timepieces are the devices that ensure radio, television and mobile-phone transmissions stay in sync, prevent the internet from turning into a mess of missing data packets, make GPS accurate enough to navigate by, and safeguard electricity grids from blackout. They are, in short, the heartbeat of modern life.

These are momentous times for Gill and others like him in timekeeping laboratories around the world. A new generation of atomic tickers, known as optical clocks, have just wrested the record for accuracy from the ensembles of oscillating caesium atoms that held it for half a century. Soon, the new technology will be so refined that if such a clock had ticked away every second since the big bang 13.7 billion years ago, it would not yet have missed a beat. That is an awesome accomplishment - but it's also a problem. At this astonishing precision, we might have to rethink not only how we measure time, but also our concept of time.

Info

Squid symbiosis may shed light on disease

The Japanese bobtail squid and luminescent marine bacteria live in blissful harmony: the bacteria have a home in the squid's light organ while producing for the squid rippling patterns of light to confuse prey or predators. The way bacteria form this symbiotic relationship may now shed light of another kind, on human disease.

Only some strains of the bacterium Vibrio fischeri will colonise squid, while other bacteria of the same species live happily in fish but avoid squid. Mark Mandel and colleagues at the University of Wisconsin in Madison report this week that a single gene makes all the difference: fish bacteria will colonise squid if given a gene carried by their squid-friendly kin (Nature, DOI: link).

Rocket

NASA plans to take the boom out of supersonic flight

NASA has completed a delicate set of flight tests to measure how modifications to an F-15 jet can affect the way shock waves form. The results could help turn sonic booms into distant rumbles.

The measurements will be used to calibrate a computer model of shock wave propagation which will be a crucial aid for engineers designing a new generation of quieter supersonic aircraft. "We're pretty close to being able to control sonic booms," says Peter Cohen of NASA's Langley Research Center in Virginia, principal investigator for the agency's supersonic research programme.

Shock waves form at the front and back of supersonic aircraft as they shove air out of the way. When these shock waves hit the ground, observers hear them as a single boom. Public opposition to booms has led to a ban on civilian supersonic flight over US land, and this key factor has discouraged further development of supersonic planes.

Info

Conflict brews over science in US stimulus package

Biomedical research is among the big winners, and physics among the losers, in the latest deal-making over the mammoth US economic stimulus bill.

The US Senate is today expected to pass an amended version of the stimulus package (pdf format), which is expected to cost an estimated $838 billion (pdf format).

Overall, science fared well in the Senate. According to an analysis by the American Association for the Advancement of Science, the Senate bill includes $17.8 billion for research and development, including $2 billion for new facilities and equipment - compared to $13.2 billion in the version previously passed by the House of Representatives.

Magnify

Vertebrates, Including Humans, Share Teeth Genes

The same molecular toolkit may control tooth formation in cichlid fish and humans.

Teeth
© Fraser et al., PLoS BiologyTwo different species of cichlids (Dimidiochromis compressiceps on the left and Labeotropheus fuelleborni on the right) have species-specific patterns and numbers of teeth in the mouth (top) and throat (bottom).
The small teeth lining cichlid fishes' throats won't make it into any baby scrapbooks, but the nubs have helped researchers figure out how vertebrates got their chompers. Research has uncovered what may be a shared toolkit of genes "common to the first tooth and all of its descendents," a team reports online February 10 in PLoS Biology. Tooth formation is likely controlled similarly in cichlids and in humans, the study suggests.

"The genes in fish are the genes that make teeth in humans," says coauthor Gareth Fraser of Georgia Institute of Technology in Atlanta.

Vertebrates cut their teeth about half a billion years ago in the seas. Pearly whites first showed up in ancient eel-like fish called conodonts, described by Fraser as "jawless beasts that roamed the seas with rows and rows of teeth in their throats."

Meteor

Scientists Unravelling Mysteries of Saskatchewan Meteorite

Milley
© Geoff Howe/Canadian PressOn Nov. 28, Ellen Milley posed with fragments of a 10-tonne meteorite she found in a small pond approximately 40 kilometres from Lloydminster, Sask.
Researchers who found chunks of a meteorite in Saskatchewan last November believe they're getting close to answering a key question: where in space did it come from?

University of Calgary graduate student Ellen Milley, who was part of the team that found space rocks in an area known as Buzzard Coulee southeast of Lloydminster, was at the University of Saskatchewan in Saskatoon Monday to talk about what the team has learned.

So far, it looks like the meteorite didn't come from the asteroid belt beyond the orbit of Mars, she said.

The road to reaching that conclusion began when the space rocks fell Nov. 20.

It was a night when hundreds of people across Western Canada witnessed a spectacular fireball across the sky caused by the estimated 10-tonne rock.

Saturn

Holographic Universe Might Conceal Many Other Dimensions

Viennese scientists are trying to grasp the mysteries of the holographic principle: How many dimensions are there in our universe?

"A hologram, as you find it on bank notes or credit cards, appears to show a three-dimensional picture, even though in fact it is just two-dimensional," Daniel Grumiller explained. He is at the Institute of Theoretical Physics, Vienna University of Technology.

For decades, scientists have been wondering about the existence of additional dimensions so far hidden to our senses.

Grumiller and his colleagues are trying the opposite approach: Instead of postulating additional dimensions, they believe that our universe could in fact be described by less than four dimensions.

Cell Phone

Nine-year-old writes hit iPhone app

You might think you're pretty hot stuff because you've figured out how to change your Facebook status from your iPhone, but you've got nothing on nine-year-old Lim Ding Wen.

This young prodigy from Singapore is fluent in six programming languages, according to a BBC report this week, and his newest creation, an iPhone drawing game called Doodle Kids, has racked up over 4,000 downloads in just two weeks. He wrote it for his younger sisters, who love to draw.