© Reuters/John KolesidisGreece's Prime Minister Antonis Samaras (2nd L) attends the ''Initiative Against the Crisis'' news conference by Stavros Niarchos foundation at Zappeion hall in Athens February 18, 2013.
Representing about 2.5 million workers, the unions have gone on strike repeatedly since Europe's debt crisis erupted in late 2009, testing the government's will to implement necessary reforms in the face of growing public anger.
"The (strike) is our answer to the dead-end policies that have squeezed the life out of workers, impoverished society and plunged the economy into recession and crisis," said the private sector union GSEE, which is organizing the walkout with its public sector sister union ADEDY.
"Our struggle will continue for as long as these policies are implemented," it said.
Prime Minister Antonis Samaras's eight-month-old coalition government has been eager to show it will implement reforms it promised the European Union and International Monetary Fund, which have bailed Athens out twice with over 200 billion euros.
It has taken a tough line on striking workers, invoking emergency law twice this year to order seamen and subway workers back to the job after week-long walkouts that paralyzed public transport in Athens and led to food shortages on islands.
But in a sign it is buckling under pressure, it announced on Monday it would not fire almost 1,900 civil servants earmarked for possible dismissal, despite promising foreign lenders it would seek to cut the public payroll.
Strikes Picking Up
Strikes have picked up in recent weeks, underscoring Greeks' anger at record high unemployment and poverty levels. A one-day visit by French President Francois Hollande in Athens on Tuesday went largely uncovered as Greek journalists were on strike.
In northern and central Greece, farmers have been protesting at high production costs and fuel prices for nearly a month, occasionally blocking the country's main north-south highway.
Most business and public sector activity is expected to come to a halt during Wednesday's strike, with school teachers, train and bus employees and bankers among various groups joining the walkout.
Hospitals will have only emergency staff and ships will stay in port as seaworkers plan to defy government orders to return to work.
Several marches are expected to culminate in demonstrations outside parliament on central Syntagma square, where they have often ended in violent clashes between police and protesters in the past.
Analysts said Greece securing bailout funds in December, which averted bankruptcy and ended months of uncertainty over the country's future in the euro, created expectations among Greeks that things would improve on a personal level as well.
"If these expectations are not satisfied by the summer, then whatever is left of the working class will respond with more protest," said Costas Panagopoulos, head of Alco pollsters.
Additional reporting by Tatiana Fragou; writing by Karolina Tagaris
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