The Vancouver-based Dr. Gabor Maté argues that too many doctors seem to have forgotten what was once a commonplace assumption - that emotions are deeply implicated in both the development of illness and in the restoration of health. Based on medical studies and his own experience with chronically ill patients at the Palliative Care Unit at Vancouver Hospital, where he was the medical coordinator for seven years, Dr. Gabor Maté makes the case that there are important links between the mind and the immune system. He found that stress and individual emotional makeup play critical roles in an array of diseases. [includes rush transcript]
Transcript
AMY GOODMAN:Healthcare reform may be stalled in Congress, but we turn now to an issue that rarely comes up in discussions about improving our healthcare system. The relationship between emotional stress and disease, between mental an physical health, more broadly, is often considered controversial within medical orthodoxy. But my next guest argues not all aspects of illness can be reduced to facts verified by the strictest scientific techniques.
The Vancouver-based Dr. Gabor Maté argues too many doctors seem to have forgotten what was once a commonplace assumption, that emotions are deeply implicated in both the development of illness and in the restoration of health. Based on medical studies and his own experience with chronically ill patients at the Palliative Care Unit at Vancouver Hospital, where he was the medical coordinator for seven years, Dr. Gabor Maté makes the case there are important links between the mind and the immune system. He finds stress and individual emotional makeup play critical roles in an array of diseases, including cancer, heart disease, diabetes, irritable bowel syndrome, multiple sclerosis and arthritis.
Dr. Maté is the bestselling author of four books in Canada, including When the Body Says No: Understanding the Stress-Disease Connection. His latest book is In the Realm of Hungry Ghosts: Close Encounters with Addiction. We spoke with him about that book a few weeks ago on Democracy Now!. Today we explore the costs of hidden stress, Dr. Gabor Maté joining us today from Vancouver, Canada.
Welcome to Democracy Now!, Dr. Maté. Let's talk about this connection between stress, the mind-body connection.
DR. GABOR MATÉ: You know, the traditional medicines of China for 3,000 years, the ayurvedic medicine of India, and the tribal shamanic medicines of all cultures around the world have always taken for granted that mind and body can't be separated. Now, Western medicine has cleaved the two apart for, really, 2,000 years. Socrates already criticized the doctors of his day for separating the mind from the body. And the irony - in fact, the tragedy - is that now we have the Western science that shows, incontrovertibly and in great detail, that mind and body can't be separated, and so that any attempt to do so leaves the medical practitioner short of many tools to help clients. And, of course, it leaves patients short of what they need for their own healing.
The point now is that the emotional centers of the brain, which regulate our behaviors and our responses and our reactions, are physiologically connected with - and we know exactly how they're connected - with the immune system, the nervous system and the hormonal apparatus. In fact, it's no longer possible, scientifically, to speak of these as separate systems, as if immunity was separate from emotions, as if the nervous system was separate from the hormonal apparatus. There's one system, and they're wired together by the nervous system itself and joined together by chemical messengers that they all secrete, and so that whatever happens emotionally has an impact immunologically, and vice versa. So, for example, we know now that the white cells in the circulation of our - of the blood can manufacture every hormone that the brain can manufacture, and vice versa, so that the brain and the immune system are always talking to one another.
So, in short, we have one system. The science that studies it is called psychoneuroimmunology. And scientifically, it's not even controversial, but it's completely lacking from medical practice.
AMY GOODMAN: What do you mean, Dr. Maté, by the mind-body - by the Bermuda Triangle?
DR. GABOR MATÉ: Well, the Bermuda Triangle is that the research is done. For example, let me give you a couple of examples. Three years ago or four years ago, a study presented at the Heart and Stroke Foundation's International Congress on Women's Health, a study that was written up in the online version of a major North American medical journal called Circulation, showed that women - over a ten-year period, they followed 1,700 women - over a ten-year period, women who were unhappily married and didn't express their emotions were four times as likely to die as those women who were unhappily married and did express their feelings. In other words, the non-expression of emotion was associated with a 400 percent increase in the death rate. And this study was done in the States, part of a major population study.
Now, you would think that study would send every physician in North America trying to figure out the mind-body connection. But these studies get published, and they sink without a trace. There was a study two years ago that showed that children of mothers who are stressed and depressed are themselves, the children, are more likely to have asthma. Again, the mind-body connection. You'd think that study alone would send every physician running to figure out the mind-body connection. But again, these studies are done; they disappear without a trace, and they have no impact on medical practice. And that's what I mean by the Bermuda Triangle, is that we have the research; we just don't pay attention to it, as like if it never happened.
AMY GOODMAN: You talk about emotions like anger sharing with our immune system the same role of defending our boundaries, saying when we repress emotions, we may also repress our immune defenses. How does that play out in various diseases?
DR. GABOR MATÉ: Well, when I looked at the kind of people that would be coming under my care in palliative care, but also the kind of people who would get sick when I was in family practice, a number of salient characteristics presented themselves. One was the repression of anger. People didn't know how to express negative emotion. They were afraid to do so or did not know when they were angry. People who were pleasers, they tried to always not to disappoint other people. They never knew how to say no. They took on everything without a murmur, because they saw their role as always being the caregivers and the caretakers. And they had an exceedingly powerful sense of duty, role and responsibility.
Now, if you look at the role of healthy assertion of boundaries and anger, for example, it's actually there to protect you. I'm talking about healthy anger. It's not there to attack anybody; it's just there to protect your boundaries. That's the same role as the immune system have. The immune system also functions like a brain. It has memory, it has reactive capacity, and it has learning capacity. In fact, the immune system has been called the "floating brain." And it's in interaction with the brain up in our heads.
Now, women, for example, with breast cancer, who don't know how to express anger, they've been shown to have diminished activity of a group of immune cells called natural killer cells. Natural killer cells attack foreign bacteria, virus and also malignant cells. In other words, they protect our boundaries. Women who don't know how to express their boundaries emotionally, they suppress their boundaries immunologically, and therefore they're more likely to develop disease. The same is true, of course, of men, so that the immune system is in constant interaction with our emotional responses.
In another study with the immune system, medical students under the stress of examination were found to have diminished activity of their natural killer cells, these immune cells. But those students who were emotionally isolated were most likely to have diminished activity of their immune system. In other words, another fact that's important is our relationship with other people. And the Los Angeles UCLA psychiatrist, Dr. Daniel Siegel, has coined a phrase "interpersonal neurobiology," to indicate that our biology of our brains, but indeed of our whole bodies, is in interaction with our personal relationships. So how we express ourselves in those relationships, or how we suppress ourselves, has a lot to do with our health.
AMY GOODMAN: You talk particularly about autoimmune diseases and their connection - well, that mind-body connection, like, for example, rheumatoid arthritis.
DR. GABOR MATÉ: A case example I give in the book is a young woman who was preparing Rosh Hashanah dinner one night for the family, Rosh Hashanah being the Jewish new year that falls in September. I called her "Rachel" in the book. And she was working very hard. She was at her mother's place cooking dinner, and she was in a real hurry, because she had to finish by 5:00, when her brother was going to arrive with his family, and he didn't like her. He didn't want to be at the dinner. So she had to finish the dinner and leave before he arrived. And I asked her, "Are you serious? You're making dinner for a family that you're not going to take part in yourself? Why?" And she said, "Well, because the family should be together for Rosh Hashanah, shouldn't they?"
Well, she never finished the meal. Her body said no. She came down with severe inflammation in all her joints, and she was rushed to the hospital with her first malignant outbreak of rheumatoid arthritis. And that self-suppression is typical for people that develop rheumatoid arthritis.
It's also typical for people that develop ALS, amyotrophic lateral sclerosis. I talk about the example of Lou Gehrig, if I may tell you about that. Lou Gehrig was this great baseball player, a teammate of Babe Ruth's on the New York Yankees. And he set a record for consecutive games played that stood for nearly sixty years. Now, Gehrig wasn't just a great athlete. He was also dutiful. He - it's not that he was never hurt. At one point, his hands were x-rayed. It turns out his fingers had been fractured seventeen separate times. And his teammates described him as grimacing like a mad monkey in agony when he fielded the ball. But he never took himself out of a game, because he was too dutiful to his own self-image and also to the fans and to the owners. Now, that sense of responsibility, and not looking after yourself, is totally typical of everybody who develops ALS.
And it goes back to their childhoods, because, just like with the woman with rheumatoid arthritis, she was a failure the moment she was born, because her mother conceived her to keep the marriage together with the father. The marriage broke up, and she never had the feeling that she was accepted and liked for who she was, therefore she had to become this dutiful caregiver. Lou Gehrig's father was an alcoholic, and Gehrig learned very early in life that he had to take care of others, as the children of alcoholics often do. And that then became his pattern until he could no longer drag himself around the baseball diamond because of the ALS, which in North America, of course, is known as Lou Gehrig's disease.
AMY GOODMAN: We're talking to Dr. Gabor Maté, the author of four bestselling books. His most recent is In the Realm of Hungry Ghosts: Close Encounters with Addiction, which we talked about two weeks ago on Democracy Now! Today we're talking about an earlier book, When the Body Says No: Understanding the Stress-Disease Connection.
Can you talk about children, when it comes to this? And then expand, because, Gabor, a few weeks ago we were talking about addictions, and that's both, what, heroin addiction, but expanding it to other addictions, as well, and the role of childhood. And in doing this, though you talked about it before, talk about your own.
DR. GABOR MATÉ: Well, again, in the book When the Body Says No, I give the example of my visiting my mother one day in a nursing home. My mother had muscular dystrophy, which is a degenerative disease of the muscles. It's hereditary, runs in our family. And so, she could no longer walk, get out of bed, even feed herself very well, so she was in a nursing home, mentally completely with it and emotionally very strong.
So I'm walking down the hall of the nursing home that day, and I'm limping a little bit. And why am I limping? Because that morning I had arthroscopic surgery on my knee, which I had to have because I tore up cartilage in my knee jogging on cement. So I have a little bit of a limp that afternoon. When I get to my mother's room, I suppress the limp. The limp disappears. I walk to her bed nonchalantly, greet her, we have a lovely visit. I walk out of the room with a perfectly normal gait, and when I shut the door behind me, my limp begins again.
And only later on did I think, "What am I doing here?" It wasn't conscious. I didn't do it deliberately. Of course, clearly, I was trying to protect my mom from the awareness of my pain. Now, my mother, at age seventy-eight, did not need to be protected from the fact that her middle-age son had to be with a limp the day of surgery. It was a childhood-ingrained mechanism going back, again, to my first year of life in the ghetto of Budapest, when, as I mentioned in my first visit to your program, we lived under Nazi occupation, a Jewish family. My father was away in forced labor. My mother was a highly stressed woman, trying to do her best to ensure my and her survival, which she was barely able to do. I learned as an infant to suppress my pain to protect her from it, because she already had too much, in order to protect my relationship with her. Now, those emotional patterns are ingrained in children from early on. And although I have no recollection of that time in my life, the memory of it lives in my cells and lives in my brain and shows up in my interactions with people, including in that example of trying to protect my mother.
So, the point is that human beings are shaped very early by what happens to them in life. As a matter of fact, they're shaped already by what happens in uterus. After 9/11, after the World Trade disasters in those terrorist attacks, some women who were pregnant suffered PTSD, post-traumatic stress disorder. And depending on what stage of pregnancy they suffered the PTSD, when they measured their children's cortisol levels - cortisol being a body stress hormone - at one year of age, those kids had abnormal cortisol levels. In other words, their stress apparatus had been negatively affected by the mother's stress during pregnancy. Similarly, for example, when I looked at the stress hormone levels of the children of Holocaust survivors with PTSD, the greater the degree of PTSD of the parent, the higher the stress hormone level of the child.
So, how we see the world, whether the world is a hostile or friendly place, whether we have to always do for ourselves and look after others or whether we can actually expect and receive help from the world, whether or not the world is hostile or friendly, and indeed our stress physiology, is very much shaped by those early experiences. And that's then what we act out much of our lives, and that's then what interferes and affects our health later on.
The implication of this, Amy, for treatment is that when somebody comes in with a first episode of rheumatoid arthritis or multiple sclerosis, or even a diagnosis of cancer, it's not enough to give them pills. It's not enough to give them radiation or offer them surgery. They should also be talked to and invited to and encouraged to investigate how they live their lives and how they stress themselves, because I can tell you from personal experience and observation that people who do that, who take a broader approach to their own health, they actually do a lot better. And I know people who have survived supposedly terminal diagnoses simply because they've taken their own mind-body unity, and I would say spiritual unity, as well, seriously, and they've gone beyond a narrow medical model of treatment. And I'm not here to disparage the value of the medical approach in which I was trained. I'm just saying that it's hopelessly narrow, and it leaves many people without appropriate treatment and appropriate support.
AMY GOODMAN: Dr. Gabor Maté, you talk about adverse childhood - - adverse childhood stresses as ACEs - -
DR. GABOR MATÉ: Yes, there was a - -
AMY GOODMAN: - - and their connection also to addiction, this latest book that you have written, In the Realm of Hungry Ghosts.
DR. GABOR MATÉ: There was a number of large-scale studies in the United States done by very brilliant researchers called the ACE studies, A-C-E, adverse childhood experiences. An adverse childhood experience is a child being abused or violence in the family or a parent being jailed or extreme stress of poverty or a rancorous divorce, a parent being addicted, alcoholic and so on.
When it comes to addiction, these effects are addictive, so that if a child has a number of these adverse childhood experiences, his chance of becoming a drug addict later on, or any kind of an addict, go up exponentially. So a male child with six such adverse childhood experiences has a 4,600 percent increase in the risk of him becoming an injection-using substance addict than a male child with no such experiences - in other words, a forty-six-fold increase in the risk.
And interestingly enough, those adverse childhood experiences also exponentially increase the risk of cancer and high blood pressure and heart disease and a whole range of other diseases, as well as suicide, of course, and early death. In other words, there's a real connection between early childhood adversity and how a person lives their lives and a later appearance of addiction and diseases, physical and of course mental illnesses at the same time.
And if we don't take this into account in medicine - most of the time, people are not asked about these things in doctors' offices, and they're not explored. They're not encouraged to explore their childhoods and the kind of impact that the childhood has on their adult behaviors.
AMY GOODMAN: As we wrap up this part of our discussion, what do you think are the most useful ways people can deal with stress, with the mind-body connection, both people themselves and also what doctors should be telling their patients, or what patients should be telling their doctors?
DR. GABOR MATÉ: The body has many ways of saying no: almost any symptom, a stomach ache, a back spasm, a headache, nausea, dry mouth, poor sleep, muscle tension. I'm talking about relatively minor symptoms. These are all ways of the body saying no. As of course are the more severe conditions, like psoriasis or ulcerative colitis, all the ones that I've already mentioned. These are all ways of the body saying no.
We need to, first of all, to say and pay attention to what the body is saying to us. So if we have a symptom, don't just go to the doctor and say, "Take this symptom away from me" - yeah, ask for help - but also explore what the body is saying no to. Usually you'll find that in your life you've taken on too much, you're suppressing yourself, you're trying to please others too much. You're living life along patterns that don't express who you really are. So the symptom or the disease ought to be not just something that you want to get rid of; it ought to be the beginning of an exploration and investigation of how you live your life and how you might possibly live your life differently, in a more healthy fashion.
AMY GOODMAN: And do you think modern medicine is dealing better, Western medicine, with this, with the mind-body connection?
DR. GABOR MATÉ: There are encouraging signs. There's certainly people like Jon Kabat-Zinn, who talks about stress and mindfulness, and Andrew Weil, who talks about the importance of nutrition and a more holistic approach. So there are many people doing great work.
But if I look at the profession as a whole, we're doing a dismal job. And we're spending billions of dollars on researches into cancer and so on that are never going to get us anywhere, because we ignore the life stresses that very often, if they don't by themselves cause, they certainly contribute in a major way to the onset of disease. But we're not looking at them. We're not dealing with them. And we're leaving people without the appropriate tools to restore their own health.
AMY GOODMAN: Dr. Gabor Maté, I want to thank you for being with us again, from Vancouver today, as we break the sound barrier. He is a bestselling author in Canada, now bringing him to the United States. The book we're talking about, When the Body Says No: Understanding the Stress-Disease Connection. His most recent book, just out, is called In the Realm of Hungry Ghosts: Close Encounters with Addiction.
Reader Comments
Janov has been doing this . . .
. . . since the early '70s, and his work has gone much, much deeper that that of his forebears.
Another brilliant worker in the field is Paul Vereshack [Link], whose work I have sited here several times.
Back to Janov: below is full copy of a recent newsletter:
Can Love Save our Lives? [Link]
Over the years, I have cited one study after another showing how loving parents produce healthier children in every way. I have also cited a good deal of our work noting how we have normalized stress hormones, serotonin, immune function, and vital functions (vital signs: all summed up in my book Primal Healing). There is also a good deal of evidence about how love changes animals and also makes them better suited to life. The NY Times (“The Spirit of Sisterhood” April 24, 2012) has discussed this.
Let’s look at some of the recent evidence. A growing number of studies suggest one potential mechanism linking stress and adversity in childhood and in the womb to cellular aging, disease, and mortality in humans: telomere erosion (Drury, et al., 2011; Entringer, et al., 2011; Epel, et al., 2004; Wikgren, et al., 2012). In the first prospective-longitudinal study with repeated telomere measurements in children while they experienced stress, Idan Shalev and his colleagues (Shalev, et al., 2012) tested the hypothesis that childhood violence exposure would accelerate telomere erosion from age 5 to age 10 years. “We examined telomere erosion in relation to children's exposure to violence, a salient early-life stressor, which has known long-term consequences for well-being and is a major public-health and social-welfare problem.” Violence was assessed as exposure to maternal domestic violence, frequent bullying victimization and physical maltreatment by an adult. Participants were children recruited from the Environmental-Risk Longitudinal Twin Study, a nationally representative 1994–1995 birth cohort. Each child's mean relative telomere length was measured simultaneously in baseline and follow-up DNA samples (using the ratio of telomere repeat copy numbers to single-copy gene numbers).
Compared with their counterparts, the children who experienced two or more kinds of violence exposure showed significantly more telomere erosion between the age-5 baseline and age-10, even after adjusting for sex, socioeconomic status and body mass index. “This finding provides support for a mechanism linking cumulative childhood stress to telomere maintenance, observed already at a young age, with potential impact for life-long health.”
So here again, if you’re subject to violence you may live less long. But don’t forget the violence done to you in the womb when mother smokes or drinks, or is very anxious--that trauma occurs so early that it cannot be observed. Yet it happens when the whole neurobiologic system is just being organized, and it severely impacts the baby. The trauma is there, and can be implied through biologic measurements that I have discussed previously in my works, and in shorter telomeres in later life (Entringer, et al., 2011). One measurement, cortisol/stress hormone levels, rise, indicating the baby has suffered and is suffering inside. No one seems to notice, least of all, the baby/child/adult. But telomeres tell us: look out, there is misery there. And when there is overt suffering, as in violent homes, the telomeres shorten, resulting in our being on earth for a much shorter time. We sometimes can say, “I was hit every day after school,” but it is hard to say, “I was ignored every day after school.” The punishment and hurt is still there.
Unloving homes may also be terribly traumatic with effects on the telomeres. One way we know is that our entering patients, nearly all, begin therapy with high stress levels. And those levels, as shown in our vital sign and cortisol studies, move toward normal after our therapy. And we do know that chronically high levels of cortisol indicate possible telomere shortening. These patients are not all aware of their suffering when they start therapy. But the read-out screams suffering.
In almost every mammal there is the expression of love in one way or another. Chimps groom each other, while elephants rub trunks. Monkeys hug and kiss each other. There is something about touching and rubbing that shows love in almost every species. We need to translate that to humans who think that saying “I love you” is enough. It is not. It comes from the top and is not physical. If you could groom your child, rub his head and his back and cuddle him every morning—that is love and it has a direct physical effect. It is saying, “I am giving you life and I will help you be healthy and live a long time.” And, Oh yes, I will lengthen your telomeres. It is not hard to do, that rubbing and hugging, yet if we do it every day with the children we will rear great kids. It is that easy. You leave yourself 10 minutes very morning to brush your teeth and do your hair; take another 10 minutes and cuddle and kiss. That is all you need to do. Just kiss and hug and then watch. And that is very hard to do with a child who was unwanted; who was in the way and came at an inconvenient time. Faking it won’t do it. It is a feeling we are after. And sometimes resentment is there first and foremost; the child never had chance, unwanted from the start. And he will be resented for getting born.
It may seem like magic, all this, but it is not. The magic is love. It begins by fulfilling each and every need; in the womb it means a healthy life, no drugs, and proper nutrients. At birth, it means a natural one with no anesthetics if possible, with holding the baby immediately close to mother’s body, in a warm, calm environment. And, of course, to avoid cesarean whenever possible. I list what happens in my new book, Life Before Birth, when a good birth does not happen.
From then on, it means touch and hugs, listening to the child’s moods and understanding and reacting to them: I am just trying to list what I never got that made me a wreck in childhood to suss out what the needs are. It means caring and being interested in the child; not being distracted and occupied elsewhere in your mind. Being close to the child emotionally means he will be able to be close to others without fear. He won’t hang back and hide behind mother’s skirt in the presence of strangers. A loved child doesn’t do that. I have had loved children around me. They are always a joy. I can pick out in a group of children which child has been loved and had a good birth. I have done it before with success. They are different; they are normal. They act normal, look normal and their bodies are normal. Don’t forget the body in the talk about normalcy. That is what any psychotherapy should aim for. It is what we all want and need.
What we do not want is a therapist setting up some arbitrary goal of normality, and then guiding us toward it, so that we end up leading his life, his wants and desires, and not ours. It is our own body and brain that dictates a goal, if needed at all, and leads us to it. If we are normal we will lead a normal life. If we concentrate on behavior alone we will never be well. We must focus on the whole system that gives rise to that behavior. We can go to therapy and try to learn to act normal, and then we die prematurely from early lack of love. Remember, it is an act. If you were not loved early on it has to be an act. We do not grow out of our childhood; we only grow away from it.
Most mammals have pals or love objects that they hang with. It gives them strength to deal with life. Mice who have pals give birth to more offspring. They are giving life. A lioness will suckle another mother’s baby…giving love and life. A close friend is soothing and calming.
The critical period for when to be loved is closed early in life and that is that. Daddy leaves home soon after his baby is born, comes back years later and wants to make up for lost time with his kids. He can’t. It is too late. It helps a bit but does not change anything. It softens some of the blow and prevents serious compounding of the imprint. The kid still feels unwanted and unloved…it is an immutable imprint. We cannot erase history, but let me tell you what we can do about it….
It seems crazy but I believe it to be true. You cannot change your telomeres and stress hormones by an act of will; it changes as part of a systemic change. But in a session, if you feel unloved within that early timeframe, you can normalize and live longer; and I believe the telomeres will not shorten as fast. Let me repeat: if you can go back in time to feel fully unloved when the imprint was laid down you will live longer. If you cannot do that and want to get on with life, life will bite you back and make you die sooner. I think that is a biologic law. You have to feel your need again; it is biologic.
When we get love very early in life it endures for a lifetime; it becomes the world’s best painkiller. And it avoids the need for later painkillers and tranquilizers. Love loads us up for a very long time with natural anti-pain medication. And when it was not there, we play catch-up all of our lives, taking pills to ease the pain over the love we never got. A love we never knew existed. So what to do? It is so easy to love a child from the day she is born; and that is pure prevention for a lifetime. It ensures health and longevity. Who can ask for more?
Drury, S.S., Theall, K.P., Gleason, M.M., Smyke, A.T., Devivo, I., Wong, J.Y.Y., Fox, N.A., Zeanah, C.H. and Nelson, C.A. (2011, epub). Telomere length and early severe social deprivation: Linking early adversity and cellular aging. Molecular Psychiatry, 1-9.
Entringer, S., Epel, E.S., Kumsta, R., Lin, J., Hellhammer, D.H., Blackburn, E.H., Wüst, S., and Wadhwa, P.D., et al. (2011) Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood. Proc Natl Acad Sci USA, 108:33, E513-E518.
Epel, E.S., Blackburn, E.H., Lin, J., Dhabhar, F.S., Adler, N.E., Morrow, J.D. and Cawthon, R.M. (2004) Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA, 101(49):17312–17315.
Shalev, I., Moffitt, T.E., Sugden, K., Williams, B., Houts, R.M., Danese, A., Mill, J., Arseneault, L. and Caspi, A. (2012) Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study. Molecular Psychiatry advance online publication 24 April 2012; doi: 10.1038/mp.2012.32
Wikgren, M., Maripuu, M., Karlsson, T., Nordfjäll, K., Bergdahl, J., Hultdin, J., Del-Favero, J., Roos, G., Nilsson, L., Adolfsson, R., Norrback, K. (2012) Short Telomeres in Depression and the General Population Are Associated with a Hypocortisolemic State. Biological Psychiatry, 71:4, 294-300.
. . . since the early '70s, and his work has gone much, much deeper that that of his forebears.
Another brilliant worker in the field is Paul Vereshack [Link], whose work I have sited here several times.
Back to Janov: below is full copy of a recent newsletter:
Can Love Save our Lives? [Link]
Over the years, I have cited one study after another showing how loving parents produce healthier children in every way. I have also cited a good deal of our work noting how we have normalized stress hormones, serotonin, immune function, and vital functions (vital signs: all summed up in my book Primal Healing). There is also a good deal of evidence about how love changes animals and also makes them better suited to life. The NY Times (“The Spirit of Sisterhood” April 24, 2012) has discussed this.
Let’s look at some of the recent evidence. A growing number of studies suggest one potential mechanism linking stress and adversity in childhood and in the womb to cellular aging, disease, and mortality in humans: telomere erosion (Drury, et al., 2011; Entringer, et al., 2011; Epel, et al., 2004; Wikgren, et al., 2012). In the first prospective-longitudinal study with repeated telomere measurements in children while they experienced stress, Idan Shalev and his colleagues (Shalev, et al., 2012) tested the hypothesis that childhood violence exposure would accelerate telomere erosion from age 5 to age 10 years. “We examined telomere erosion in relation to children's exposure to violence, a salient early-life stressor, which has known long-term consequences for well-being and is a major public-health and social-welfare problem.” Violence was assessed as exposure to maternal domestic violence, frequent bullying victimization and physical maltreatment by an adult. Participants were children recruited from the Environmental-Risk Longitudinal Twin Study, a nationally representative 1994–1995 birth cohort. Each child's mean relative telomere length was measured simultaneously in baseline and follow-up DNA samples (using the ratio of telomere repeat copy numbers to single-copy gene numbers).
Compared with their counterparts, the children who experienced two or more kinds of violence exposure showed significantly more telomere erosion between the age-5 baseline and age-10, even after adjusting for sex, socioeconomic status and body mass index. “This finding provides support for a mechanism linking cumulative childhood stress to telomere maintenance, observed already at a young age, with potential impact for life-long health.”
So here again, if you’re subject to violence you may live less long. But don’t forget the violence done to you in the womb when mother smokes or drinks, or is very anxious--that trauma occurs so early that it cannot be observed. Yet it happens when the whole neurobiologic system is just being organized, and it severely impacts the baby. The trauma is there, and can be implied through biologic measurements that I have discussed previously in my works, and in shorter telomeres in later life (Entringer, et al., 2011). One measurement, cortisol/stress hormone levels, rise, indicating the baby has suffered and is suffering inside. No one seems to notice, least of all, the baby/child/adult. But telomeres tell us: look out, there is misery there. And when there is overt suffering, as in violent homes, the telomeres shorten, resulting in our being on earth for a much shorter time. We sometimes can say, “I was hit every day after school,” but it is hard to say, “I was ignored every day after school.” The punishment and hurt is still there.
Unloving homes may also be terribly traumatic with effects on the telomeres. One way we know is that our entering patients, nearly all, begin therapy with high stress levels. And those levels, as shown in our vital sign and cortisol studies, move toward normal after our therapy. And we do know that chronically high levels of cortisol indicate possible telomere shortening. These patients are not all aware of their suffering when they start therapy. But the read-out screams suffering.
In almost every mammal there is the expression of love in one way or another. Chimps groom each other, while elephants rub trunks. Monkeys hug and kiss each other. There is something about touching and rubbing that shows love in almost every species. We need to translate that to humans who think that saying “I love you” is enough. It is not. It comes from the top and is not physical. If you could groom your child, rub his head and his back and cuddle him every morning—that is love and it has a direct physical effect. It is saying, “I am giving you life and I will help you be healthy and live a long time.” And, Oh yes, I will lengthen your telomeres. It is not hard to do, that rubbing and hugging, yet if we do it every day with the children we will rear great kids. It is that easy. You leave yourself 10 minutes very morning to brush your teeth and do your hair; take another 10 minutes and cuddle and kiss. That is all you need to do. Just kiss and hug and then watch. And that is very hard to do with a child who was unwanted; who was in the way and came at an inconvenient time. Faking it won’t do it. It is a feeling we are after. And sometimes resentment is there first and foremost; the child never had chance, unwanted from the start. And he will be resented for getting born.
It may seem like magic, all this, but it is not. The magic is love. It begins by fulfilling each and every need; in the womb it means a healthy life, no drugs, and proper nutrients. At birth, it means a natural one with no anesthetics if possible, with holding the baby immediately close to mother’s body, in a warm, calm environment. And, of course, to avoid cesarean whenever possible. I list what happens in my new book, Life Before Birth, when a good birth does not happen.
From then on, it means touch and hugs, listening to the child’s moods and understanding and reacting to them: I am just trying to list what I never got that made me a wreck in childhood to suss out what the needs are. It means caring and being interested in the child; not being distracted and occupied elsewhere in your mind. Being close to the child emotionally means he will be able to be close to others without fear. He won’t hang back and hide behind mother’s skirt in the presence of strangers. A loved child doesn’t do that. I have had loved children around me. They are always a joy. I can pick out in a group of children which child has been loved and had a good birth. I have done it before with success. They are different; they are normal. They act normal, look normal and their bodies are normal. Don’t forget the body in the talk about normalcy. That is what any psychotherapy should aim for. It is what we all want and need.
What we do not want is a therapist setting up some arbitrary goal of normality, and then guiding us toward it, so that we end up leading his life, his wants and desires, and not ours. It is our own body and brain that dictates a goal, if needed at all, and leads us to it. If we are normal we will lead a normal life. If we concentrate on behavior alone we will never be well. We must focus on the whole system that gives rise to that behavior. We can go to therapy and try to learn to act normal, and then we die prematurely from early lack of love. Remember, it is an act. If you were not loved early on it has to be an act. We do not grow out of our childhood; we only grow away from it.
Most mammals have pals or love objects that they hang with. It gives them strength to deal with life. Mice who have pals give birth to more offspring. They are giving life. A lioness will suckle another mother’s baby…giving love and life. A close friend is soothing and calming.
The critical period for when to be loved is closed early in life and that is that. Daddy leaves home soon after his baby is born, comes back years later and wants to make up for lost time with his kids. He can’t. It is too late. It helps a bit but does not change anything. It softens some of the blow and prevents serious compounding of the imprint. The kid still feels unwanted and unloved…it is an immutable imprint. We cannot erase history, but let me tell you what we can do about it….
It seems crazy but I believe it to be true. You cannot change your telomeres and stress hormones by an act of will; it changes as part of a systemic change. But in a session, if you feel unloved within that early timeframe, you can normalize and live longer; and I believe the telomeres will not shorten as fast. Let me repeat: if you can go back in time to feel fully unloved when the imprint was laid down you will live longer. If you cannot do that and want to get on with life, life will bite you back and make you die sooner. I think that is a biologic law. You have to feel your need again; it is biologic.
When we get love very early in life it endures for a lifetime; it becomes the world’s best painkiller. And it avoids the need for later painkillers and tranquilizers. Love loads us up for a very long time with natural anti-pain medication. And when it was not there, we play catch-up all of our lives, taking pills to ease the pain over the love we never got. A love we never knew existed. So what to do? It is so easy to love a child from the day she is born; and that is pure prevention for a lifetime. It ensures health and longevity. Who can ask for more?
Drury, S.S., Theall, K.P., Gleason, M.M., Smyke, A.T., Devivo, I., Wong, J.Y.Y., Fox, N.A., Zeanah, C.H. and Nelson, C.A. (2011, epub). Telomere length and early severe social deprivation: Linking early adversity and cellular aging. Molecular Psychiatry, 1-9.
Entringer, S., Epel, E.S., Kumsta, R., Lin, J., Hellhammer, D.H., Blackburn, E.H., Wüst, S., and Wadhwa, P.D., et al. (2011) Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood. Proc Natl Acad Sci USA, 108:33, E513-E518.
Epel, E.S., Blackburn, E.H., Lin, J., Dhabhar, F.S., Adler, N.E., Morrow, J.D. and Cawthon, R.M. (2004) Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA, 101(49):17312–17315.
Shalev, I., Moffitt, T.E., Sugden, K., Williams, B., Houts, R.M., Danese, A., Mill, J., Arseneault, L. and Caspi, A. (2012) Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study. Molecular Psychiatry advance online publication 24 April 2012; doi: 10.1038/mp.2012.32
Wikgren, M., Maripuu, M., Karlsson, T., Nordfjäll, K., Bergdahl, J., Hultdin, J., Del-Favero, J., Roos, G., Nilsson, L., Adolfsson, R., Norrback, K. (2012) Short Telomeres in Depression and the General Population Are Associated with a Hypocortisolemic State. Biological Psychiatry, 71:4, 294-300.
Very Good Video
Thanks. It adds a lot as to how one can observe oneself to look for clues about what is wrong, and dealing with the "why". I'm going to buy those two books of his.
Thanks. It adds a lot as to how one can observe oneself to look for clues about what is wrong, and dealing with the "why". I'm going to buy those two books of his.
Do yourself a favor and buy them as soon as you can. He is a wonderful author and great study.
One of his earlier works called "Scattered" saved my life when I was 16. I was about to walk in front of a moving bus before I found it. It helped me realize how much about myself that I had tried to throw away or suppress.
And I like the no-nonsense way that the presents his arguments and he does it in a way where you don't need a medical degree, or an open tab on a medical dictionary, to understand.
One of his earlier works called "Scattered" saved my life when I was 16. I was about to walk in front of a moving bus before I found it. It helped me realize how much about myself that I had tried to throw away or suppress.
And I like the no-nonsense way that the presents his arguments and he does it in a way where you don't need a medical degree, or an open tab on a medical dictionary, to understand.
And he started writing and speaking about it publicly in 1950.
So I think it's about time that "modern" medicine got a little more on top of this phenomenon.
Hubbard developed all sorts of assists to help people recover from disease and physical trauma, yet the medical establishment has been one of his more vigorous enemies.
I think it's time we all took another look.