Many agricultural pesticides disrupt male hormones, according to new tests.

Many agricultural pesticides - including some previously untested and commonly found in food - disrupt male hormones, according to new tests conducted by British scientists.

The scientists strongly recommended that all pesticides in use today be screened to check if they block testosterone and other androgens, the hormones critical to a healthy reproductive system for men and boys.

"Our results indicate that systematic testing for anti-androgenic activity of currently used pesticides is urgently required," wrote the scientists from University of London's Centre for Toxicology, led by Professor Andreas Kortenkamp.

Thirty out of 37 widely used pesticides tested by the group blocked or mimicked male hormones. Sixteen of the 30 had no known hormonal activity until now, while there was some previous evidence for the other 14, according to the study, published online last Thursday in the scientific journal Environmental Health Perspectives.

A federal government report on antibiotic resistance reveals that superbugs in meat is a much more common and widespread problem than anyone would like to admit. New strains of hearty, antibiotic resistant salmonella, E. coli and campylobacter bacteria appear to be showing up in alarmingly high percentages of the chicken, turkey, pork and beef we buy at the supermarket.

These findings come from a little-noticed report the FDA released back in December. The report, which was dumped onto the FDA's web site without so much as a mention or a press release, compiles data from 5,236 samples of chicken breasts, ground turkey, ground beef and pork chops that were taken in 2008. It's unclear why the FDA either waited or took so long to release the info.

On her blog, Maryn McKenna, author of a book about antibiotic resistance called Superbug and the first person to write about the report, summarized some of the findings: In 2008, 45% of salmonella on chicken were resistant to the antibiotic tetracycline and 30% were immune to penicillins. Among enterococci bacteria on chicken, 65% were resistant to tetracycline and more than 90% to lincosamides, which include the everyday drug clindamycin.

If you follow the news about health research, you risk whiplash. First garlic lowers bad cholesterol, then - after more study - it doesn't. Hormone replacement reduces the risk of heart disease in postmenopausal women, until a huge study finds that it doesn't (and that it raises the risk of breast cancer to boot). Eating a big breakfast cuts your total daily calories, or not - as a study released last week finds. Yet even if biomedical research can be a fickle guide, we rely on it.

But what if wrong answers aren't the exception but the rule? More and more scholars who scrutinize health research are now making that claim. It isn't just an individual study here and there that's flawed, they charge. Instead, the very framework of medical investigation may be off-kilter, leading time and again to findings that are at best unproved and at worst dangerously wrong. The result is a system that leads patients and physicians astray - spurring often costly regimens that won't help and may even harm you.

It's a disturbing view, with huge im-plications for doctors, policymakers, and health-conscious consumers. And one of its foremost advocates, Dr. John P.A. Ioannidis, has just ascended to a new, prominent platform after years of crusading against the baseless health and medical claims. As the new chief of Stanford University's Prevention Research Center, Ioannidis is cementing his role as one of medicine's top mythbusters. "People are being hurt and even dying" because of false medical claims, he says: not quackery, but errors in medical research.

Johnson & Johnson is recalling 70,000 syringes preloaded with its Invega injectable anti-psychotic drug, the WSJ reports. Cracks have been found in the syringes that could theoretically lead to infections or under-dosing in users of Invega Sustenna, though the company said that risk is low. (One report of an adverse event in Australia may be linked to the problem.)

We've been keeping tabs on J&J's string of recalls, which cost it about $900 million in sales last year. Here's a running list:

Dr. Maurice Hilleman made astounding revelations in an interview that was cut from The Health Century -- the admission that Merck drug company vaccines had been injecting dangerous viruses into people worldwide.

Bear in mind that Dr. Hilleman was the developer of Merck's vaccine program. He developed over three dozen vaccines, more than any other scientist in history. He was a member of the U.S. National Academy of Science, the Institute of Medicine, the American Academy of Arts and Sciences, and the American Philosophical Society. He received a special lifetime achievement award from the World Health Organization. Hilleman was one of the early vaccine pioneers to warn about the possibility that simian viruses might contaminate vaccines.

Sources:

The PPJ Gazette February 6, 2011
Paging Dr. Gupta, CNN Health February 1, 2011
PR Log January 24, 2011

A spike in global food prices has pushed millions more into poverty since last summer, said World Bank president Robert Zoellick

The World Bank has given a stark warning of the impact of the rising cost of food, saying an estimated 44 million people had been pushed into poverty since last summer by soaring commodity prices.

Robert Zoellick, the Bank's president, said food prices had risen by almost 30% in the past year and were within striking distance of the record levels reached during 2008.

"Global food prices are rising to dangerous levels and threaten tens of millions of poor people around the world," Zoellick said. "The price hike is already pushing millions of people into poverty, and putting stress on the most vulnerable, who spend more than half of their income on food."

Jiongchiri, South Korea-- More than 140 cases of foot-and-mouth disease (FMD) have been confirmed nationwide in South Korea and millions of cows and pigs have been culled, but Lim Kang-soo never believed his cows could fall victim to this highly contagious animal disease.

Lim, a resident of Jeongchiri near Gongju in South Chungcheong Province, confidently invested his life savings into a small cow farm, believing in its notoriously strict vaccination policies -- until eight of his cattle tested positive for FMD last month.

"We sterilized ourselves head to toe whenever we stepped in and out of the shed," Lim said."Our village is tucked away deep in the hills, 60 kilometers away from the closest FMD case. How could this have happened?"

An independent investigation, commissioned by the Icheon municipality west of Seoul and released last week, gave weight to the argument that transmission by air and not direct contact might have been the primary force behind the rapid spread of the lethal airborne virus.

US researchers said Friday they have found that people who used two specific varieties of pesticide were 2.5 times as likely to develop Parkinson's disease.

The pesticides, paraquat and rotenone, are not approved for house and garden use. Previous research on animals has linked paraquat to Parkinson's disease, so it is restricted to use by certified applicators.

Rotenone is approved only for use in killing invasive fish species.

"Rotenone directly inhibits the function of the mitochondria, the structure responsible for making energy in the cell," said study co-author Freya Kamel, a researcher at the National Institute of Environmental Health Sciences.

The first Dietary Goals for the United States (DGUS) were released in 1977 to not a lot of fanfare. At that time, the great unwashed masses hadn't really heard much about the word cholesterol, a substance the DGUS recommended that we should limit to 300 mg per day. Doctors didn't routinely screen for it, and if they did, they didn't pay much attention to it. In fact, at that time - as I recall, anyway - the upper limit of normal for total cholesterol was 240 mg/dl. I was in medical school back then, and I don't really remember any emphasis on cholesterol or blood lipids. I think we had one lecture on it in biochemistry, given by a nebbish little professor we called Mighty Manford (his first name was Manford), who labored away in the obscurity of the biochemistry department. It's hard to believe in today's world of lipophobia that as little as 30 years ago, no one much cared about cholesterol.

One of the major players in bringing cholesterol to the public's awareness was Time magazine. Its piece on cholesterol in the March 26, 1984 issue was a devastating hit piece on both dietary cholesterol and dietary fat. Both - the article explained - were a main driving force behind the development of heart disease.

Reading this article today, it's amazing how it drips with misinformation. At the time, however, most people - physicians included - accepted it as gospel. Sadly, even today, many physicians who should know better believe in and act in accordance to the bountiful misinformation contained in this piece.

I could write a blog longer than the article (and it's a long article) describing and dissecting all the many errors, but I'm going to go over just one. And that one just briefly. But before I get to that, let me show you just a few of interesting small parts of the article beginning with the very first sentence:

An ingredient used in Coca-Cola and Pepsi is a cancer risk and should be banned, an influential lobby group has claimed.

The concerns relate to an artificial brown colouring agent that the researchers say could be causing thousands of cancers.

'The caramel colouring used in Coca-Cola, Pepsi, and other foods is contaminated with two cancer-causing chemicals and should be banned,' said the Center for Science in the Public Interest (CSPI), a health lobby group based in Washington, DC.