© Alena Sefcakova, Slovak National Museum, Bratislava, SlovakiaAn X-ray of vertebrae from a 50–to 60–year–old man exhumed from an early medieval cemetery in Slovakia showed damage from what paleopathologists believe was metastatic carcinoma – a cancer that began in the soft tissues of the body and spread to the bone.
When they excavated a Scythian burial mound in the Russian region of Tuva about 10 years ago, archaeologists literally struck gold. Crouched on the floor of a dark inner chamber were two skeletons, a man and a woman, surrounded by royal garb from 27 centuries ago: headdresses and capes adorned with gold horses, panthers and other sacred beasts.
But for paleopathologists - scholars of ancient disease - the richest treasure was the abundance of tumors that had riddled almost every bone of the man's body. The diagnosis: the oldest known case of metastasizing prostate cancer.
The prostate itself had disintegrated long ago. But malignant cells from the gland had migrated according to a familiar pattern and left identifiable scars. Proteins extracted from the bone tested positive for PSA, prostate specific antigen.
Often thought of as a modern disease, cancer has always been with us. Where scientists disagree is on how much it has been amplified by the sweet and bitter fruits of civilization. Over the decades archaeologists have made about 200 possible cancer sightings dating to prehistoric times. But considering the difficulties of extracting statistics from old bones, is that a little or a lot?
A recent report by two Egyptologists in the journal
Nature Reviews: Cancer reviewed the literature, concluding that there is "a striking rarity of malignancies" in ancient human remains.
"The rarity of cancer in antiquity suggests that such factors are limited to societies that are affected by modern lifestyle issues such as tobacco use and pollution resulting from industrialization," wrote the authors, A. Rosalie David of the University of Manchester in England and Michael R. Zimmerman of Villanova University in Pennsylvania. Also on the list would be obesity, dietary habits, sexual and reproductive practices, and other factors often altered by civilization.
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